Explanipedia

Psychological Vulnerability During Pregnancy and Its Obstetric Consequences: A Multidimensional Approach Open

Ioana Denisa Socol, Ahmed Abu-Awwad, Flavius George Socol, Simona Sorina Farcaș, Simona-Alina Abu-Awwad , et al. · 2025

Background/Objectives: Maternal depression, anxiety, perceived stress, and resilience are recognized determinants of perinatal health, yet routine psychological screening is still uncommon in Romanian obstetric practice. This study examine…

Analysis of COVID-19-related psychiatric disorders: clinical manifestations and therapeutic considerations Open

O. Vasiliu, Andrei G. Mangalagiu, Bogdan M. Petrescu, Cristian A. Cândea, Corina Tudor , et al. · 2022

During the COVID-19 pandemic, neuropsychiatric disorders have been diagnosed both in the acute phase, and in the aftermath of this disease. Inpatients, as well as outpatients recently diagnosed with mild, moderate or severe forms of Corona…

Orthorexia nervosa – a different lifestyle or a specific eating disorder? Open

D. Vasile, O. Vasiliu · 2022

Orthorexia nervosa (ON) is considered an obsession with healthy eating, a phenomenon that includes excessive dietary restrictions, which in turn can lead to metabolic dysfunctions. Although the nosological status of this pathology is curre…

Tratamentul farmacologic bazat pe dovezi al dependenţei de jocuri de noroc Open

D. Vasile, O. Vasiliu · 2021

Pathological gambling is a diagnostic undergoing continuous reassessment, being considered an impulse-control disorder, a behavioral addiction assimilated with a substance-related disorder, or even a disorder from the obsessive-compulsive …

Aspecte de diagnostic şi tratament al tulburărilor asociate stresului profesional la personalul medical în contexul pand Open

O. Vasiliu, Ileana Marinescu, D. Vasile · 2021

Healthcare professionals are confronted with multiple stressors in their daily practice and data from the literature support a higher incidence of stress-related disorders, as well as isolated symptoms of such disorders in physicians and a…

Changes in sleep quality amidst COVID-19 pandemic among psychiatric patients in Romania Open

Maria Petrescu, Adina Mitrea, Corneliu Tudor, D. Vasile · 2021

Introduction Sleep disturbances can occur as a result of major stressful events. Additionally, research evidence suggests that COVID-19 pandemic may have negatively impacted the quality of sleep among various populations. However, individu…

Evaluation of executive dysfunction in clinical practice- pragmatic challenges and solutions Open

D. Vasile, O. Vasiliu · 2021

Introduction Executive dysfunction (ED) is an important clinical dimension that need to be evaluated in neurologic and psychiatric disorders, due to this factor’s impact over patients functionality, quality of life, and overall prognosis. …

Mindfulness-based cognitive therapy for major depressive disorder- a literature review Open

D. Vasile, O. Vasiliu, A.G. Mangalagiu, B.M. Petrescu, Corneliu Tudor , et al. · 2021

Introduction Mindfulness-based cognitive therapy (MBCT) is a third wave cognitive-behavioral therapy (CBT) that incorporates meditation exercises in the classical, structured intervention. Mindfulness has been associated with psychological…

Evidence-based therapeutic management of binge-eating disorder Open

D. Vasile, O. Vasiliu · 2021

Introduction Binge-eating disorder (BED) is a difficult-to-manage clinical entity, that may associate both organic (e.g., obesity, metabolic syndrome) and psychiatric (e.g., anxiety, mood, or substance use disorders) co-morbidity. Psychoth…

Third generation cognitive-behavioral therapies for major depressive disorder- a literature review Open

D. Vasile, O. Vasiliu, D.G. Vasiliu · 2021

Introduction Cognitive behavioral therapies (CBT) represent a heterogeneous group of psychotherapies in continuous development that share a directive, structured, collaborative approach. Due to a high degree of treatment-resistant cases of…

Psychotherapies for neurocognitive disorder due to alzheimer’s disease- the current level of evidence Open

D. Vasile, O. Vasiliu, D.G. Vasiliu · 2021

Introduction Psychosocial interventions for Alzheimer’s dementia (AD) may increase patients quality of life and overall functioning, while it decreases caregivers burden. Therefore psychotherapies represent an important component of the ca…

Evidence-based pharmacological strategies for gambling disorder Open

D. Vasile, O. Vasiliu · 2021

Pathological gambling is a diagnostic undergoing continuous reassessment, being considered an impulse-control disorder, a behavioral addiction assimilated with a substance-related disorder, or even a disorder from the obsessive-compulsive …

Diagnostic and treatment features of work stress-related disorders in healthcare professionals in the context of COVID-19 pandemic Open

O. Vasiliu, Ileana Marinescu, D. Vasile · 2021

Healthcare professionals are confronted with multiple stressors in their daily practice and data from the literature support a higher incidence of stress-related disorders, as well as isolated symptoms of such disorders in physicians and a…

Current treatment of posttraumatic stress disorder – A review of therapeutic guidelines and good practice recommendations Open

O. Vasiliu, D. Vasile, Andrei Mangalagiu, Bogdan Petrescu, Cristian A. Cândea , et al. · 2020

A unique approach to the treatment of posttraumatic stress disorder (PTSD) is difficult to support, because of the complexity and heterogeneity of this pathology. Multiple evidence-based guidelines for PTSD treatment exist, elaborated by p…

Eficacitatea terapiilor cognitiv-comportamentale din a treia generaţie – o analiză narativă a literaturii (II) Open

O. Vasiliu, Ileana Marinescu, D. Vasile · 2020

Cognitive-behavioral therapies (CBTs) do not represent a single, conceptual and practical, psychosocial intervention, but a developing group of directive, structured, collaborative psychotherapies, which benefit from an important level of …

Managementul terapeutic al tulburării neurocognitive în boala Alzheimer Open

D. Vasile, O. Vasiliu · 2020

Background. According to a meta-analysis conducted by S. Gauthier (2015), Cerebrolysin® was significantly superior to placebo at 4 weeks and 6 months in mild-to-moderate Alzheimer’s disease (AD), while its safety was comparable to placebo.…

Managementul terapeutic al tulburărilor legate de consumul de substanţe (I) Open

Ileana Marinescu, O. Vasiliu, D. Vasile · 2020

Substance use disorders (SUD) are some of the greatest challenges in clinical practice, because of their tendency to become chronic, to associate various complications, to decompensate underlying psychiatric or somatic disorders, to increa…

Efficacy analysis of the third generation of cognitive-behavioral therapies – a narrative literature review (II) Open

O. Vasiliu, Ileana Marinescu, D. Vasile · 2020

Cognitive-behavioral therapies (CBTs) do not represent a single, conceptual and practical, psychosocial intervention, but a developing group of directive, structured, collaborative psychotherapies, which benefit from an important level of …

Efficacy analysis of the third generation of cognitive-behavioral therapies – a narrative literature review Open

O. Vasiliu, Ileana Marinescu, D. Vasile · 2020

Cognitive-behavioral therapies (CBTs) do not represent a single, conceptual and practical, psychosocial intervention, but a developing group of directive, structured, collaborative psychotherapies, which benefit from an important level of …

Therapeutic management of substance use disorders (II) Open

O. Vasiliu, Ileana Marinescu, D. Vasile · 2020

The available treatments for substance use disorders (SUD) involving nicotine, cannabis, caffeine, hallucinogens, psychostimulants, hydrocarbon-based inhalants and new psychoactive drugs are discussed in this narrative review, together wit…

Therapeutic management of major neurocognitive disorder due to Alzheimer’s disease* Open

D. Vasile, O. Vasiliu · 2020

Background. According to a meta-analysis conducted by S. Gauthier (2015), Cerebrolysin® was significantly superior to placebo at 4 weeks and 6 months in mild-to-moderate Alzheimer’s disease (AD), while its safety was comparable to placebo.…

Therapeutic management of substance use disorders (I) Open

Ileana Marinescu, O. Vasiliu, D. Vasile · 2020

Substance use disorders (SUD) are some of the greatest challenges in clinical practice, because of their tendency to become chronic, to associate various complications, to decompensate underlying psychiatric or somatic disorders, to increa…

Actualităţi în terapia tulburării de alimentaţie compulsivă Open

Ileana Marinescu, O. Vasiliu, D. Vasile · 2019

Binge eating disorder (BED) is a frequent diagnosis especially in adolescents, but it is also met as the main pathology or as a comorbidity in the adult population. The evolution of BED is influenced by the presence of associated psychiatr…

Tratamentul farmacologic al depresiei post-stroke Open

O. Vasiliu, Ileana Marinescu, D. Vasile · 2019

Post-stroke depression is a very challenging condition because it involves the existence of a frail biological and psychological background. The clinician must therefore observe carefully the clinical context before the initiation of a tre…

S55. THERAPEUTIC MANAGEMENT OF PATIENTS DIAGNOSED WITH SCHIZOPHRENIA AND MAJOR NEUROCOGNITIVE DISORDER DUE TO ALZHEIMER’S DISEASE - A CASE SERIES Open

O. Vasiliu, D. Vasile, D.G. Vasiliu, F. Vasile · 2019

Patients with schizophrenia present a higher risk for the development of neurocognitive disorders, according to data in the literature [1]. A common pathogenic background has been reported as being the dysfunction of the N-methyl-D-asparta…

Pharmacological therapy of post-stroke depression Open

O. Vasiliu, Ileana Marinescu, D. Vasile · 2019

Post-stroke depression is a very challenging condition because it involves the existence of a frail biological and psychological background. The clinician must therefore observe carefully the clinical context before the initiation of a tre…

Modern approaches in the treatment of compulsive eating disorders Open

Ileana Marinescu, O. Vasiliu, D. Vasile · 2019

Binge eating disorder (BED) is a frequent diagnosis especially in adolescents, but it is also met as the main pathology or as a comorbidity in the adult population. The evolution of BED is influenced by the presence of associated psychiatr…

17.1 A RANDOMIZED CONTROLLED TRIAL OF CANNABIDIOL IN SCHIZOPHRENIA Open

Philip McGuire, Philip Robson, Wieslaw Jerzy Cubała, D. Vasile, Paul Morrison , et al. · 2018

Both preclinical and human research suggest that cannabidiol (CBD) has antipsychotic properties. This study assessed the safety and effectiveness of CBD in patients with schizophrenia. Patients with schizophrenia (n=88) were randomized to …

Analysis of risk factors for antipsychotic-resistant schizophrenia in young patients – A retrospective analysis Open

O. Vasiliu, D. Vasile, A. F. Fainarea, M. C. Patrascu, Elena A. Morariu , et al. · 2018

Treatment resistant schizophrenia (TRS) is a severely disabling disorder, which decreases dramatically the quality of life and overall functionality, while it increases the rate of hospital admissions and overall healthcare costs. The main…

The Xth National Conference of Biological Psychiatry and Psychopharmacology Open

T. Udriştoiu, Marinescu Dragoș, Romania Umph Of Craiova, Lavinia Duică, Victor Gheorman , et al. · 2017

The pathogenesis of Alzheimer's Disease assumes two models.The first involves the genetic spectrum and is characterized by early onset and rapid cognitive decline.The second relies on a pluri-factorial vulnerability, where the role of gene…

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