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View article: Metabolic bariatric surgery, alcohol misuse and liver cirrhosis: a narrative review
Metabolic bariatric surgery, alcohol misuse and liver cirrhosis: a narrative review Open
Bariatric surgery and liver cirrhosis have considerable overlap. Bariatric procedures intend to reduce metabolic dysfunction-associated steatotic liver disease (MASLD); however, these procedures are thought to increase the propensity for a…
View article: Social Isolation, Loneliness and Generalized Anxiety: Implications and Associations during the COVID-19 Quarantine
Social Isolation, Loneliness and Generalized Anxiety: Implications and Associations during the COVID-19 Quarantine Open
The COVID-19 pandemic has resulted in a predominantly global quarantine response that has been associated with social isolation, loneliness, and anxiety. The foregoing experiences have been amply documented to have profound impacts on heal…
View article: Strategies to Prolong Ketamine’s Efficacy in Adults with Treatment-Resistant Depression
Strategies to Prolong Ketamine’s Efficacy in Adults with Treatment-Resistant Depression Open
Introduction: Ketamine treatment is capable of significant and rapid symptom improvement in adults with treatment-resistant depression (TRD). A limitation of ketamine treatment in TRD is the relatively short duration of time to relapse (e.…
View article: Brain structural networks and connectomes: the brain–obesity interface and its impact on mental health
Brain structural networks and connectomes: the brain–obesity interface and its impact on mental health Open
We extend knowledge further by delineating structural interconnectivity alterations within and across brain regions that are adversely affected in individuals who are obese.
View article: Stability, reliability, and validity of the THINC‐it screening tool for cognitive impairment in depression: A psychometric exploration in healthy volunteers
Stability, reliability, and validity of the THINC‐it screening tool for cognitive impairment in depression: A psychometric exploration in healthy volunteers Open
Objectives There is a need for a brief, reliable, valid, and sensitive assessment tool for screening cognitive deficits in patients with Major Depressive Disorders. This paper examines the psychometric characteristics of THINC‐it, a cognit…
View article: Predictors of Response to Ketamine in Treatment Resistant Major Depressive Disorder and Bipolar Disorder
Predictors of Response to Ketamine in Treatment Resistant Major Depressive Disorder and Bipolar Disorder Open
Objectives: Extant evidence indicates that ketamine exerts rapid antidepressant effects in treatment-resistant depressive (TRD) symptoms as a part of major depressive disorder (MDD) and bipolar disorder (BD). The identification of depresse…
View article: Air pollution, aeroallergens and suicidality: a review of the effects of air pollution and aeroallergens on suicidal behavior and an exploration of possible mechanisms
Air pollution, aeroallergens and suicidality: a review of the effects of air pollution and aeroallergens on suicidal behavior and an exploration of possible mechanisms Open
Objective: Risk factors for suicide can be broadly categorized as sociodemographic, clinical and treatment. There is interest in environmental risk and protection factors for suicide. Emerging evidence suggests a link between environmental…
View article: Pain and major depressive disorder: Associations with cognitive impairment as measured by the THINC-integrated tool (THINC-it)
Pain and major depressive disorder: Associations with cognitive impairment as measured by the THINC-integrated tool (THINC-it) Open
Objectives To examine the role of pain on cognitive function in adults with major depressive disorder (MDD). Methods Adults (18–65) with a Diagnostic and Statistical Manual – Fifth Edition (DSM-5)-defined diagnosis of MDD experiencing a cu…
View article: Assessing and measuring cognitive function in major depressive disorder
Assessing and measuring cognitive function in major depressive disorder Open
Cognitive dysfunction is a major component of major depressive disorder (MDD). No ‘gold-standard’ tool exists for the assessment of cognitive dysfunction for adults with MDD. The use of measurement-based care to improve treatment outcomes …
View article: The prevalence and clinical characteristics associated with Diagnostic and Statistical Manual Version-5-defined anxious distress specifier in adults with major depressive disorder: results from the International Mood Disorders Collaborative Project
The prevalence and clinical characteristics associated with Diagnostic and Statistical Manual Version-5-defined anxious distress specifier in adults with major depressive disorder: results from the International Mood Disorders Collaborative Project Open
Objectives: The aim of the study was to evaluate the prevalence of and illness characteristics in adults with major depressive disorder (MDD) with anxious distress specifier (ADS) enrolled in the International Mood Disorders Collaborative …