Danielle Wolfs
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View article: Maternal Physical Activity and Its Relationship to the Human Milk Metabolome and Infant Body Composition
Maternal Physical Activity and Its Relationship to the Human Milk Metabolome and Infant Body Composition Open
Context Exercise is recommended for postpartum health, but its effects on breast milk composition and offspring are understudied. Objective This work aimed to test whether the breast milk metabolome is altered with (i) acute exercise and/o…
View article: Type 2 diabetes impacts DNA methylation in human sperm
Type 2 diabetes impacts DNA methylation in human sperm Open
NCT03860558.
View article: 8026 Growth Hormone Receptor (GHR) is Independently Associated with Body Composition and Glycemic Measures in Youth with Type 2 Diabetes (T2D)
8026 Growth Hormone Receptor (GHR) is Independently Associated with Body Composition and Glycemic Measures in Youth with Type 2 Diabetes (T2D) Open
Disclosure: C. Lu: None. D. Wolfs: None. L. El ghormli: None. L.M. Laffel: None. M. Patti: Advisory Board Member; Self; Fractyl Health. Consulting Fee; Self; AstraZeneca, Hamni, MBX Biosciences. Grant Recipient; Self; Dexcom. E. Isganaitis…
View article: Circulating metabolite biomarkers of glycemic control in youth-onset type 2 diabetes
Circulating metabolite biomarkers of glycemic control in youth-onset type 2 diabetes Open
Objective. We aimed to identify metabolites associated with loss of glycemic control in youth-onset type 2 diabetes. Research design and methods. We measured 480 metabolites in fasting plasma samples from the Treatment Options for type 2 d…
View article: Circulating metabolite biomarkers of glycemic control in youth-onset type 2 diabetes
Circulating metabolite biomarkers of glycemic control in youth-onset type 2 diabetes Open
Objective. We aimed to identify metabolites associated with loss of glycemic control in youth-onset type 2 diabetes. Research design and methods. We measured 480 metabolites in fasting plasma samples from the Treatment Options for type 2 d…
View article: Growth Hormone Mediators and Glycemic Control in Youths With Type 2 Diabetes
Growth Hormone Mediators and Glycemic Control in Youths With Type 2 Diabetes Open
Importance Youth-onset type 2 diabetes (T2D) has a more aggressive phenotype than adult-onset T2D, including rapid loss of glycemic control and increased complication risk. Objective To identify associations of growth hormone mediators wit…
View article: Pramlintide for <scp>post‐bariatric</scp> hypoglycaemia
Pramlintide for <span>post‐bariatric</span> hypoglycaemia Open
Aims The aim of this study was to examine the hypothesis that pramlintide would reduce hypoglycaemia by slowing gastric emptying and reducing postprandial glucagon secretion, thus limiting postprandial glycaemic excursions and insulin secr…
View article: Brown Fat–Activating Lipokine 12,13-diHOME in Human Milk Is Associated With Infant Adiposity
Brown Fat–Activating Lipokine 12,13-diHOME in Human Milk Is Associated With Infant Adiposity Open
Context Little is known about the specific breastmilk components responsible for protective effects on infant obesity. Whether 12,13-dihydroxy-9Z-octadecenoic acid (12,13-diHOME), an oxidized linoleic acid metabolite and activator of brown…