D. Marković
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View article: Lipid peroxidation, detoxification capacity, and genome damage in mice after transplacental exposure to pharmaceutical drugs
Lipid peroxidation, detoxification capacity, and genome damage in mice after transplacental exposure to pharmaceutical drugs Open
Data on genome damage, lipid peroxidation, and levels of glutathione peroxidase (GPX) in newborns after transplacental exposure to xenobiotics are rare and insufficient for risk assessment. The aim of the current study was to analyze, in a…
View article: Toll-like receptor 2 mediates microglia/brain macrophage MT1-MMP expression and glioma expansion
Toll-like receptor 2 mediates microglia/brain macrophage MT1-MMP expression and glioma expansion Open
Our results thus show that activation of TLR2 along with TLRs 1 and/or 6 converts microglia into a glioma supportive phenotype.
View article: Optimization of the growth of and a-amylase production by Bacillus subtilis IP 5832 in shake flask and laboratory fermenter batch cultures
Optimization of the growth of and a-amylase production by Bacillus subtilis IP 5832 in shake flask and laboratory fermenter batch cultures Open
The stabilities and antioxidant action of two selected flavonoids, quercetin and rutin, dissolved in methanol and water, toward continuous UV-irradiation from three different sub-ranges (UV-A, UV-B and UV-C) were studied. The flavonoids un…
View article: Animal model for age- and sex-related genotoxicity of diethylstilbestrol
Animal model for age- and sex-related genotoxicity of diethylstilbestrol Open
Environmental xenoestrogens pose a significant health risk for all living organisms. There is growing evidence concerning the different susceptibility to xenoestrogens of developing and adult organisms, but little is known about their geno…
View article: Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion
Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion Open
Diffuse infiltration of glioma cells into normal brain tissue is considered to be a main reason for the unfavorable outcomes of patients with malignant gliomas. Invasion of glioma cells into the brain parenchyma is facilitated by metallopr…
View article: The invasion promoting effect of microglia on glioblastoma cells is inhibited by cyclosporin A
The invasion promoting effect of microglia on glioblastoma cells is inhibited by cyclosporin A Open
The invasion of tumour cells into brain tissue is a pathologic hallmark of WHO grades II-IV gliomas and contributes significantly to the failure of current therapeutic treatments. Activated microglial cells are abundant in brain tumours an…