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View article: Cleavage of N-terminus of polycystin-1 increases calcium permeability of polycystin-1/2 receptor channel complexes
Cleavage of N-terminus of polycystin-1 increases calcium permeability of polycystin-1/2 receptor channel complexes Open
Mutations on genes encoding polycystin-1 (PC1) and PC2 cause autosomal-dominant polycystic kidney disease. How these 2 proteins work together to exert anticystogenesis remains elusive. PC1 resembles adhesion G-protein coupled receptors and…
View article: Insight into the Conformational Transitions of Serine Acetyl Transferase Isoforms in <i>E. histolytica</i>: Implications for Structural and Functional Balance
Insight into the Conformational Transitions of Serine Acetyl Transferase Isoforms in <i>E. histolytica</i>: Implications for Structural and Functional Balance Open
Serine acetyl transferase (SAT) is one of the crucial enzymes in the cysteine biosynthetic pathway and an essential enzyme for the survival of Entamoeba histolytica, the causative agent of amoebiasis. E. histolytica expresses three isoform…
View article: Carbonic Anhydrase II Based Biosensing of Carbon Dioxide at High Temperature: An Analytical and MD Simulation Study
Carbonic Anhydrase II Based Biosensing of Carbon Dioxide at High Temperature: An Analytical and MD Simulation Study Open
Concentration of carbon dioxide (CO2) in the atmosphere has increased significantly due to anthropogenic
\nactivities and attributed as a major factor to global warming. Its detection by biosensing methods will provide an
\nalternative for…
View article: CCDC 1564724: Experimental Crystal Structure Determination
CCDC 1564724: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1564722: Experimental Crystal Structure Determination
CCDC 1564722: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1564721: Experimental Crystal Structure Determination
CCDC 1564721: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1564723: Experimental Crystal Structure Determination
CCDC 1564723: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: GdmCl-induced unfolding studies of human carbonic anhydrase IX: a combined spectroscopic and MD simulation approach
GdmCl-induced unfolding studies of human carbonic anhydrase IX: a combined spectroscopic and MD simulation approach Open
Carbonic anhydrase IX (CAIX) is a transmembrane glycoprotein, associated with tumor, acidification which leads to the cancer, and is considered as a potential biomarker for hypoxia-induced cancers. The overexpression of CAIX is linked with…