Danlan Zhang
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View article: <scp>miR</scp>‐223‐3p Mitigates Mitochondrial Dysfunction and Cementoblast Apoptosis in Orthodontic Root Resorption via <scp>FoxO3</scp>
<span>miR</span>‐223‐3p Mitigates Mitochondrial Dysfunction and Cementoblast Apoptosis in Orthodontic Root Resorption via <span>FoxO3</span> Open
Aim The aim of this study was to elucidate the roles of miR‐223‐3p in orthodontically induced inflammatory root resorption (OIIRR). Methods We used high‐throughput miRNA sequencing and transcriptome sequencing to analyze the differentially…
View article: Vitamin A family suppresses periodontitis by restoring mitochondrial metabolic reprogramming in macrophages through JAK-STAT pathway
Vitamin A family suppresses periodontitis by restoring mitochondrial metabolic reprogramming in macrophages through JAK-STAT pathway Open
Objective Mitochondrial metabolic reprogramming in macrophages is crucial in the development and progression of inflammation. Given vitamin A’s antioxidant properties and its therapeutic effects on inflammation, this study aims to elucidat…
View article: Hippo-signaling-controlled MHC class I antigen processing and presentation pathway potentiates antitumor immunity
Hippo-signaling-controlled MHC class I antigen processing and presentation pathway potentiates antitumor immunity Open
The major histocompatibility complex class I (MHC class I)-mediated tumor antigen processing and presentation (APP) pathway is essential for the recruitment and activation of cytotoxic CD8+ T lymphocytes (CD8+ CTLs). …
View article: YBX1 as an oncogenic factor in T-cell acute lymphoblastic leukemia
YBX1 as an oncogenic factor in T-cell acute lymphoblastic leukemia Open
Y-box-binding protein 1 (YBX1), a member of the RNA-binding protein family, is a critical regulator of cell survival in various solid tumors and acute myeloid leukemia. However, the function of YBX1 in T-cell acute lymphoblastic leukemia (…