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View article: Sodium Houttuybonate Promotes the Browning of White Adipose Tissue by Inhibiting Ferroptosis via the AMPK-NRF2-HO1 Pathway
Sodium Houttuybonate Promotes the Browning of White Adipose Tissue by Inhibiting Ferroptosis via the AMPK-NRF2-HO1 Pathway Open
The rising prevalence of obesity has resulted in an increased demand for innovative and effective treatment strategies. Houttuynia cordata Thunb. (H. cordata) has demonstrated promising potential in preventing obesity. However, the mechani…
View article: Alternate day fasting aggravates atherosclerosis through the suppression of hepatic ATF3 in <i>Apoe−/−</i> mice
Alternate day fasting aggravates atherosclerosis through the suppression of hepatic ATF3 in <i>Apoe−/−</i> mice Open
Atherosclerosis is the major contributor to cardiovascular mortality worldwide. Alternate day fasting (ADF) has gained growing attention due to its metabolic benefits. However, the effects of ADF on atherosclerotic plaque formation remain …
View article: Cytokine receptor-like factor 1 (CRLF1) promotes cardiac fibrosis via ERK1/2 signaling pathway
Cytokine receptor-like factor 1 (CRLF1) promotes cardiac fibrosis via ERK1/2 signaling pathway Open
Cardiac fibrosis is a cause of morbidity and mortality in people with heart disease. Anti-fibrosis treatment is a significant therapy for heart disease, but there is still no thorough understanding of fibrotic mechanisms. This study was ca…
View article: Predictive value of live birth rate based on different intrauterine adhesion evaluation systems following TCRA
Predictive value of live birth rate based on different intrauterine adhesion evaluation systems following TCRA Open
Objective The aim of this study was to assess the predictive value of five different intrauterine adhesion (IUA) evaluation systems for live birth rate following transcervical resection of adhesion (TCRA). Method This retrospective study i…
View article: Predictive value of live birth rate based on different intrauterine adhesion evaluation systems following TCRA
Predictive value of live birth rate based on different intrauterine adhesion evaluation systems following TCRA Open
Objective : The aim of this study was to assess the predictive value of five different intrauterine adhesion (IUA) evaluation systems for live birth rate following transcervical resection of adhesion (TCRA). Method : This retrospective stu…
View article: Predictive Value of Live Birth Rate Based on Different Intrauterine Adhesion Evaluation Systems Following
Predictive Value of Live Birth Rate Based on Different Intrauterine Adhesion Evaluation Systems Following Open
Objective: The aim of this study was to assess the predictive value of five different intrauterine adhesion (IUA) evaluation systems for live birth rate following transcervical resection of adhesion (TCRA).Method: This retrospective study …
View article: Defining the Learning Curve is Necessary to Improve Oocyte Retrieval Skills: Lessons from A Single High-Volume Reproductive CenterDefining the Learning Curve is Necessary to Improve Oocyte Retrieval Skills: Lessons from A Single High-Volume Reproductive Center
Defining the Learning Curve is Necessary to Improve Oocyte Retrieval Skills: Lessons from A Single High-Volume Reproductive CenterDefining the Learning Curve is Necessary to Improve Oocyte Retrieval Skills: Lessons from A Single High-Volume Reproductive Center Open
Objective: The objective of this study was to determine the novice trainee’s learning curve for oocytes retrieval procedure through assessment of oocytes retrieval efficiency, operative time and other operative characteristics. Methods: Th…
View article: Development and Validation of a Prognostic Prediction Model for Postoperative Ovarian Sex Cord-Stromal Tumor Patients
Development and Validation of a Prognostic Prediction Model for Postoperative Ovarian Sex Cord-Stromal Tumor Patients Open
BACKGROUND We developed a nomogram for prognostic prediction of overall survival (OS) in postoperative ovarian sex cord-stromal tumor (SCST) patients and discuss the effect of chemotherapy at various FIGO stages. MATERIAL AND METHODS SCST …
View article: Research Progress on the Animal Models of Drug-Induced Liver Injury: Current Status and Further Perspectives
Research Progress on the Animal Models of Drug-Induced Liver Injury: Current Status and Further Perspectives Open
Drug-induced liver injury (DILI) is a major concern in clinical studies as well as in postmarketing surveillance. It is necessary to establish an animal model of DILI for thorough investigation of mechanisms of DILI and searching for prote…
View article: Pharmacological mechanism of roflumilast in the treatment of asthma&ndash;COPD overlap
Pharmacological mechanism of roflumilast in the treatment of asthma–COPD overlap Open
Asthma-COPD overlap (ACO) is a type of incomplete obstructive airway disease that has a high incidence and mortality. Nevertheless, there is currently no clear definition of ACO and no effective intervention. The newly discovered phosphodi…
View article: The efficacy and safety of alectinib in the treatment of ALK+ NSCLC: a systematic review and meta-analysis
The efficacy and safety of alectinib in the treatment of ALK+ NSCLC: a systematic review and meta-analysis Open
Generally, alectinib is a drug with preferable efficacy and tolerable adverse effects, and it is suitable for the treatment of intracranial metastases.