Danni Zhang
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View article: Multi-omics analysis of flavor and quality modulation in dry-fermented sausages with textured pea protein
Multi-omics analysis of flavor and quality modulation in dry-fermented sausages with textured pea protein Open
View article: Metabolomic Insights into Volatile Profiles and Flavor Enhancement of Spice-Smoked Chicken Wings
Metabolomic Insights into Volatile Profiles and Flavor Enhancement of Spice-Smoked Chicken Wings Open
Traditional smoking techniques, while historically valued for preservation and flavor enhancement, face limitations in aromatic diversity and safety, prompting exploration of spice-derived alternatives to meet modern culinary demands. This…
View article: Biodegradable Microneedle Patch Confers Crocin with Outstanding Effects in the Treatment of Myocardial Infarction
Biodegradable Microneedle Patch Confers Crocin with Outstanding Effects in the Treatment of Myocardial Infarction Open
Crocin (CRO), the main active component of Crocus sativus (saffron), exhibits significant therapeutic potential for the treatment of myocardial infarction (MI). However, its clinical application is hindered by poor oral administrati…
View article: Author Correction: CRISPR screens reveal convergent targeting strategies against evolutionarily distinct chemoresistance in cancer
Author Correction: CRISPR screens reveal convergent targeting strategies against evolutionarily distinct chemoresistance in cancer Open
View article: A New Additive for Preparing Uniform Small Pyramid Texture for N-type HJT Solar Cells
A New Additive for Preparing Uniform Small Pyramid Texture for N-type HJT Solar Cells Open
View article: Flavor Quality Characterization of Rapeseed Oil During Storage by Physicochemical Analysis, Sensory Evaluation, Electronic Nose, and GC–O
Flavor Quality Characterization of Rapeseed Oil During Storage by Physicochemical Analysis, Sensory Evaluation, Electronic Nose, and GC–O Open
Background: Rapeseed oil is the most widely consumed vegetable oil globally. However, the key aroma‐active compounds of rapeseed oil and their changes during storage are unclear. In this study, the flavor of rapeseed oil during storage was…
View article: Study on Hjt Solar Cells Characterized with Uniform Small Pyramid Texture Etched By A New Additive Containing Disodium D-Glucarate
Study on Hjt Solar Cells Characterized with Uniform Small Pyramid Texture Etched By A New Additive Containing Disodium D-Glucarate Open
View article: Acupuncture and related therapies for anxiety and depression in patients with premature ovarian insufficiency and diminished ovarian reserve: a systematic review and meta-analysis
Acupuncture and related therapies for anxiety and depression in patients with premature ovarian insufficiency and diminished ovarian reserve: a systematic review and meta-analysis Open
Background The decreased ovarian function has a negative impact on the mental health of women and increases the risk of anxiety and depression. A growing number of clinical studies have demonstrated that acupuncture-related therapies can e…
View article: Cover Image
Cover Image Open
The cover image is based on the article Identification of volatile differential markers in strong‐aroma Baijiu based on gas chromatography–electronic nose combined with gas chromatography–time‐of‐flight mass spectrometry by Aliya, Yufa Cao…
View article: Case report: A huge retroperitoneal solitary fibrous tumor closely related to the external iliac vessels misdiagnosed as an ovarian tumor
Case report: A huge retroperitoneal solitary fibrous tumor closely related to the external iliac vessels misdiagnosed as an ovarian tumor Open
Background Solitary fibrous tumor (SFT) is a rare soft tissue tumor originating from mesenchymal cells. Thus far, there have been no reported cases of SFT closely related to the iliac vessels. Case presentation An elderly woman was found t…
View article: Research on the Evaluation of Baijiu Flavor Quality Based on Intelligent Sensory Technology Combined with Machine Learning
Research on the Evaluation of Baijiu Flavor Quality Based on Intelligent Sensory Technology Combined with Machine Learning Open
Baijiu, one of the world’s six major distilled spirits, has an extremely rich flavor profile, which increases the complexity of its flavor quality evaluation. This study employed an electronic nose (E-nose) and electronic tongue (E-tongue)…
View article: CRISPR screens reveal convergent targeting strategies against evolutionarily distinct chemoresistance in cancer
CRISPR screens reveal convergent targeting strategies against evolutionarily distinct chemoresistance in cancer Open
Resistance to chemotherapy has been a major hurdle that limits therapeutic benefits for many types of cancer. Here we systematically identify genetic drivers underlying chemoresistance by performing 30 genome-scale CRISPR knockout screens …
View article: Uncommon P1 Anchor-featured Viral T Cell Epitope Preference within HLA-A*2601 and HLA-A*0101 Individuals
Uncommon P1 Anchor-featured Viral T Cell Epitope Preference within HLA-A*2601 and HLA-A*0101 Individuals Open
The individual HLA-related susceptibility to emerging viral diseases such as COVID-19 underscores the importance of understanding how HLA polymorphism influences peptide presentation and T cell recognition. Similar to HLA-A*0101, which is …
View article: CRISPR screens reveal convergent targeting strategies against evolutionarily distinct chemoresistance in cancer
CRISPR screens reveal convergent targeting strategies against evolutionarily distinct chemoresistance in cancer Open
Resistance to chemotherapy has been a major hurdle that limits therapeutic benefits for many types of cancer. Here we systematically identify genetic drivers underlying chemoresistance by performing 30 genome-scale CRISPR knockout screens …
View article: Case report: Ureteric bud intestinal-type adenocarcinoma involving the cervix was misdiagnosed as a large cervical fibroid
Case report: Ureteric bud intestinal-type adenocarcinoma involving the cervix was misdiagnosed as a large cervical fibroid Open
Background Malignant tumors of the ureteric bud are not common, and cervical involvement is even rarer. So far, there have been no such cases in the literature. Case summary A 50-year-old woman developed intermittent light bleeding in the …
View article: Characterization of CD8 <sup>+</sup> T cells in immune-privileged organs of ZIKV-infected <i>Ifnar1</i> <sup>−/−</sup> mice
Characterization of CD8 <sup>+</sup> T cells in immune-privileged organs of ZIKV-infected <i>Ifnar1</i> <sup>−/−</sup> mice Open
Zika virus (ZIKV) infection caused neurological complications and male infertility, leading to the accumulation of antigen-specific immune cells in immune-privileged organs (IPOs). Thus, it is important to understand the immunological resp…
View article: Improving the Short-Circuit Current Density of N-Type Heterogeneous Junction Solar Cells by Small Pyramid Texture Prepared by a Chemical Additive
Improving the Short-Circuit Current Density of N-Type Heterogeneous Junction Solar Cells by Small Pyramid Texture Prepared by a Chemical Additive Open
View article: Transcriptome profiling reveals the regulatory mechanisms of ascorbic acid and flavonoid synthesis and metabolic processes in fruit development of Ribes nigrum
Transcriptome profiling reveals the regulatory mechanisms of ascorbic acid and flavonoid synthesis and metabolic processes in fruit development of Ribes nigrum Open
Background The blackcurrant ( Ribes nigrum L.) is rich in nutritional value. It is rich in ascorbic acid and flavonoids with excellent antioxidant properties. Fruit quality is an important factor affecting subsequent processing and product…
View article: Disseminated tuberculosis in a child during the COVID-19 pandemic: a case report and literature review
Disseminated tuberculosis in a child during the COVID-19 pandemic: a case report and literature review Open
Background Disseminated tuberculosis is an uncommon but devastating form of tuberculosis, possibly developing with the immune response of patients. COVID-19 infection may produce an immunosuppressive effect with possible implications for t…
View article: Rare peptide anchors of HLA class I alleles contribute to the COVID-19 disease severity and T cell memory
Rare peptide anchors of HLA class I alleles contribute to the COVID-19 disease severity and T cell memory Open
View article: MdASMT9 -mediated melatonin biosynthesis enhances basal thermotolerance in apple plants
MdASMT9 -mediated melatonin biosynthesis enhances basal thermotolerance in apple plants Open
High temperature negatively impacts the yield and quality of fruit crops. Exogenous melatonin (MT) application has shown the capability to enhance heat tolerance, but the response of endogenous MT to heat stress, particularly in perennial …
View article: Inactivated vaccine fueled adaptive immune responses to Omicron in 2‐year COVID‐19 convalescents
Inactivated vaccine fueled adaptive immune responses to Omicron in 2‐year COVID‐19 convalescents Open
Over 3 years, humans have experienced multiple rounds of global transmission of SARS‐CoV‐2 and its variants. In addition, the widely used vaccines against SARS‐CoV‐2 involve multiple strategies of development and inoculation. Thus, the acq…
View article: Clinical analysis of three patients with multiple endometrial cancer lesions treated by hysteroscopic surgery combined with progesterone: Case report
Clinical analysis of three patients with multiple endometrial cancer lesions treated by hysteroscopic surgery combined with progesterone: Case report Open
Rationale: Endometrial cancer (EC) is one of three common malignant tumors of the female reproductive tract, exceeded by cervical cancer. It has an incidence rate ranging from 3% to 10% with an increasing trend in recent years. Patient con…
View article: Melatonin biosynthesis gene MdASMT9 confers tolerance to nitrogen deficiency in an MdHY5-dependent manner in apple plants
Melatonin biosynthesis gene MdASMT9 confers tolerance to nitrogen deficiency in an MdHY5-dependent manner in apple plants Open
Nitrogen (N) is a vital nutrient for crop growth and development which influences both yield and quality. Melatonin (MT), a known enhancer of abiotic stress tolerance, has been extensively studies; however, its relationship with nutrient s…
View article: Umami taste components in chicken-spices blends and potential effect of aroma on umami taste intensity
Umami taste components in chicken-spices blends and potential effect of aroma on umami taste intensity Open
In this study, umami taste intensity (UTI) and umami taste components in chicken breast (CB) and
\nchicken-spices blends were characterized using sensory and instrumental analysis. Our main objective was to assess
\nthe aroma-umami taste i…
View article: Transmission of Mycobacterium tuberculosis in schools: a molecular epidemiological study using whole-genome sequencing in Guangzhou, China
Transmission of Mycobacterium tuberculosis in schools: a molecular epidemiological study using whole-genome sequencing in Guangzhou, China Open
Background China is a country with a high burden of tuberculosis (TB). TB outbreaks are frequent in schools. Thus, understanding the transmission patterns is crucial for controlling TB. Method In this genomic epidemiological study, the con…
View article: White Matter Hyperintensities in Young Patients from a Neurological Outpatient Clinic: Prevalence, Risk Factors, and Correlation with Enlarged Perivascular Spaces
White Matter Hyperintensities in Young Patients from a Neurological Outpatient Clinic: Prevalence, Risk Factors, and Correlation with Enlarged Perivascular Spaces Open
(1) Background: to investigate the prevalence of white matter hyperintensities (WMH), risk factors, and correlation with enlarged perivascular spaces (ePVS) among young patients (age, 16–45 years) in a neurological outpatient clinic. (2) M…
View article: Inactivated vaccine fueled adaptive immune responses to Omicron in 2-year COVID-19 convalescents
Inactivated vaccine fueled adaptive immune responses to Omicron in 2-year COVID-19 convalescents Open
For nearly three years, humans have experienced multiple rounds of global transmission of SARS-CoV-2 and its variant strains. In addition, the widely used vaccines against SARS-CoV-2 involve multiple strategies of development and inoculati…
View article: Parallel T Cell Immunogenic Regions in Influenza B and A Viruses with Distinct Nuclear Export Signal Functions: The Balance between Viral Life Cycle and Immune Escape
Parallel T Cell Immunogenic Regions in Influenza B and A Viruses with Distinct Nuclear Export Signal Functions: The Balance between Viral Life Cycle and Immune Escape Open
Influenza A viruses (IAVs) and influenza B viruses (IBVs) cause annual epidemics in human populations with seasonal circulation spikes. Peptide AM58–66GL9 located at residues 58–66 of M1 protein of IAVs has been recognized as an immunodomi…
View article: Repeated influenza vaccination induces similar immune protection as first‐time vaccination but with differing immune responses
Repeated influenza vaccination induces similar immune protection as first‐time vaccination but with differing immune responses Open
Background Recent seasonal epidemics of influenza have been caused by human influenza A viruses of the H1N1 and H3N2 subtypes and influenza B viruses. Annual vaccination is recommended to prevent infection; however, how annual influenza va…