Frans Dany
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View article: The extract of zedoary-turmeric protects rats’ kidneys from damage caused by cisplatin
The extract of zedoary-turmeric protects rats’ kidneys from damage caused by cisplatin Open
Objective: The goal of this study was to examine how the combination of Curcuma zedoaria (zedoary) and Curcuma longa (turmeric) affected things on the kidneys of rats with acute kidney injury (AKI) from cisplatin by assessing the reduction…
View article: Investigation of Cisplatin-Induced Acute Kidney Injury Using LC-HRMS and Network Pharmacology Approaches in Mixed Curcuma longa and Curcuma zedoaria Extracts
Investigation of Cisplatin-Induced Acute Kidney Injury Using LC-HRMS and Network Pharmacology Approaches in Mixed Curcuma longa and Curcuma zedoaria Extracts Open
Background: Cisplatin-induced acute kidney injury (AKI) is a serious complication of cancer therapy. Natural compounds, such as those found in Curcuma species, may exert protective effects through anti-inflammatory and antioxidant mechanis…
View article: Pandemic Pressure: Changes in Hypertensive Management Adherence in Indonesia
Pandemic Pressure: Changes in Hypertensive Management Adherence in Indonesia Open
Efforts to improve adherence to hypertension management after the COVID-19 pandemic should target those who were young, highly educated, who did not have any healthcare insurance, and who did not perceive themselves as not having comorbidi…
View article: Characteristic comparison of human induced pluripotent stem cell-derived adult and fetal β-like cells: a differential gene expression analysis
Characteristic comparison of human induced pluripotent stem cell-derived adult and fetal β-like cells: a differential gene expression analysis Open
Differentiating human induced pluripotent stem cells (hiPSCs) into β cells for type 1 diabetes (T1D) management is a crucial step. Functionality characterization of hiPSC-derived β cells in some cases, however, only considers morphology an…
View article: Revisiting HPV infection pattern among urban Indonesian women in general population and its implication on health burden: A cross-sectional analysis from Indonesian Noncommunicable Disease Research 2016
Revisiting HPV infection pattern among urban Indonesian women in general population and its implication on health burden: A cross-sectional analysis from Indonesian Noncommunicable Disease Research 2016 Open
Objective: To identify circulating HPV types among urban Indonesian women and their specific co-infection patterns in bid to curb HPV infection in the general population and minimize its complications. Methods: Urban Indonesian women from …
View article: Dyslipidemia in Renal Dysfunction among Non-diabetic Individuals from the 2019 Indonesian Cohort Study: A Cross-Sectional Study
Dyslipidemia in Renal Dysfunction among Non-diabetic Individuals from the 2019 Indonesian Cohort Study: A Cross-Sectional Study Open
The aim of this study was to investigate the relationship between dyslipidemia and the estimated Glomerular Filtration Rate (eGFR) values in a healthy population without a history of diabetes mellitus.Data were part of the cohort study dat…
View article: Diagnosis of Acute Q Fever in a Patient by Using Metagenomic Next-Generation Sequencing: A Case Report [Letter]
Diagnosis of Acute Q Fever in a Patient by Using Metagenomic Next-Generation Sequencing: A Case Report [Letter] Open
We are very interested in and much appreciated the case report made by Wang et al 1 about establishing Q fever diagnosis with the help of metagenomics tools.However, we think that a few points should be addressed pertaining to potential bi…
View article: A response to article “Java sea Spirulina platensis chemical analysis and its protective ability against H2O2-exposed umbilical cord mesenchymal stem cells according to CD73, CD90, and CD105, viability, and HIF-1 alpha docking” (Letter)
A response to article “Java sea Spirulina platensis chemical analysis and its protective ability against H2O2-exposed umbilical cord mesenchymal stem cells according to CD73, CD90, and CD105, viability, and HIF-1 alpha docking” (Letter) Open
Journal of Applied Pharmaceutical Science (JAPS): A new open-Access international journal in the field of Pharmaceutical ScienceDr. Khalid Akhter Ansari
View article: The Prevalence of Combined Three Markers of Hepatitis B in Indonesia: Further Analysis of National Basic Health Research, 2013
The Prevalence of Combined Three Markers of Hepatitis B in Indonesia: Further Analysis of National Basic Health Research, 2013 Open
Hepatitis B is still a health problem in the world and Indonesia.A combination of three markers, HBsAg, anti-HBc, and anti-HBs, provides further information on the hepatitis B active infection and immunity status.Therefore, the objective o…
View article: Immunocytochemistry Studies Using Microtubule-Associated Protein-2 (MAP-2) Markers on Neural Differentiation of Mesenchymal Stem Cells from Rat Bone Marrow
Immunocytochemistry Studies Using Microtubule-Associated Protein-2 (MAP-2) Markers on Neural Differentiation of Mesenchymal Stem Cells from Rat Bone Marrow Open
Mesenchymal stem cells (MSCs) can differentiate into neurons, which can be used in cell therapy.Endogenous genes and neurotrophic factors such as nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and neurotrophin-3 regul…
View article: Evaluating Biomedical Features for Reactive Hypoglycaemia Prediction with Machine Learning
Evaluating Biomedical Features for Reactive Hypoglycaemia Prediction with Machine Learning Open
Reactive hypoglycaemia (RH) is a condition when post-prandial plasma glucose level drops, usually <70 mg/dl.Its exact cause is unknown and associated with risk of diabetes among non-diabetic individuals.Attempts are made to predict RH but …
View article: A Response to Article “Do Mesenchymal Stem Cells Influence Keloid Recurrence?” [Letter]
A Response to Article “Do Mesenchymal Stem Cells Influence Keloid Recurrence?” [Letter] Open
This is very important information about correlation between keloid and normal skin with Mesenchymal Stem Cells (MSCs) counts, proportions, and recurrence.We would like to discuss our opinions on the characterization method of MSCs and kel…
View article: A Response to Article “Rho-Associated Protein Kinase Inhibitor and Hypoxia Synergistically Enhance the Self-Renewal, Survival Rate, and Proliferation of Human Stem Cells” [Letter]
A Response to Article “Rho-Associated Protein Kinase Inhibitor and Hypoxia Synergistically Enhance the Self-Renewal, Survival Rate, and Proliferation of Human Stem Cells” [Letter] Open
We read and review the article by Alsobaie et al 1 with great interest, which studied the synergistic effect of rho-associated protein kinase (ROCK) inhibitor Y-27632 and hypoxic condition to maintain propagation of human induced-pluripote…
View article: A Response to Article “Rho-Associated Protein Kinase Inhibitor and Hypoxia Synergistically Enhance the Self-Renewal, Survival Rate, and Proliferation of Human Stem Cells” [Letter]
A Response to Article “Rho-Associated Protein Kinase Inhibitor and Hypoxia Synergistically Enhance the Self-Renewal, Survival Rate, and Proliferation of Human Stem Cells” [Letter] Open
Frans Dany, Ratih Rinendyaputri Biomedical Research Center, Health Research Organization, National Research and Innovation Agency (BRIN), Cibinong, West Java, IndonesiaCorrespondence: Frans Dany, Biomedical Research Center, Health Research…
View article: RETN Gene Single Nucleotide Polymorphism Profile on Triglyceride-Glucose Index as Insulin Resistance Proxy Among Cohort Population of Non-Communicable Diseases in Bogor
RETN Gene Single Nucleotide Polymorphism Profile on Triglyceride-Glucose Index as Insulin Resistance Proxy Among Cohort Population of Non-Communicable Diseases in Bogor Open
Genetic factors such as single nucleotide polymorphisms (SNPs) are thought to contribute to the increasing incidence of diabetes mellitus (DM) through insulin resistance. SNPs in the RETN (resistin) gene encoding the resistin protein have …
View article: Determinants of diabetes comorbidities in Indonesia: a cohort study of non-communicable disease risk factor
Determinants of diabetes comorbidities in Indonesia: a cohort study of non-communicable disease risk factor Open
BackgroundType 2 diabetes mellitus (DM) is a non-communicable disease that constitutes a huge health burden, with the presence of comorbidities of DM adding to it. This study aimed to obtain the main determinants of the combined incidence …
View article: Contribution of Metabolic Syndrome in Controlling Diabetes Mellitus According to Gender in Indonesia (RISKESDAS 2018)
Contribution of Metabolic Syndrome in Controlling Diabetes Mellitus According to Gender in Indonesia (RISKESDAS 2018) Open
BACKGROUND: Metabolic syndrome (MetS) is a multiple risk factor for the development of type 2 diabetes mellitus (DM). It is important to understand the contribution of MetS in developing DM in different population characteristics. This stu…
View article: THE EXPRESSION OF NESTIN IN THE INDUCED DIFFERENTIATION INTO NEURONS OF RAT BONE MARROW MESENCHYMAL STEM CELLS BY NEUROTROPHIN-3 (NT-3)
THE EXPRESSION OF NESTIN IN THE INDUCED DIFFERENTIATION INTO NEURONS OF RAT BONE MARROW MESENCHYMAL STEM CELLS BY NEUROTROPHIN-3 (NT-3) Open
Objective: The aim of this study was to examine the role of NT-3 as a single neurotrophic factor in the expression of nestin in the neural differentiation of MSCs.
Methods: MSCs were isolated from rat bone marrow and induced with NT-3 at …
View article: BRCA 1 and BRCA 2 Gene Sequencing in Indonesian Urban Women: Further Study of Noncommunicable Disease Research 2016
BRCA 1 and BRCA 2 Gene Sequencing in Indonesian Urban Women: Further Study of Noncommunicable Disease Research 2016 Open
Introduction: BRCA1 and BRCA2 are genes associated with the risk of hereditary breast cancer, one of the most cancer found in Indonesian women.The study of the genetic pattern of BRCA1 and BRCA2 genes in the Indonesian population is still …
View article: Cervical Cancer Risk Factor: HPV Infection Among Indonesian Urban Women
Cervical Cancer Risk Factor: HPV Infection Among Indonesian Urban Women Open
Cervical cancer is the fourth most common cancer among women worldwide.The major cause of cervical cancer is the Human Papilloma Virus (HPV) [1,2].Several studies showed that the prevalence of HPV infection varies considerably in some coun…
View article: Resistin Protein Analysis Using Receiver Operating Characteristics Curve in Predicting the Occurrence of Type 2 Diabetes Mellitus in Respondents of Cohort Study of Risk Factors for Noncommunicable Diseases in Bogor
Resistin Protein Analysis Using Receiver Operating Characteristics Curve in Predicting the Occurrence of Type 2 Diabetes Mellitus in Respondents of Cohort Study of Risk Factors for Noncommunicable Diseases in Bogor Open
Resistin is a hormone that involved in obesity and type 2 diabetes mellitus.High resistin level in pre-DM respondents with obesity will cause insulin resistance.ROC analysis is used as an initial screening to predict chronic diseases preci…
View article: Polymorphism UCP2 Gene in Predicting the Occurrence of Type 2 Diabetes Mellitus in Respondents Cohort Study of Risk Factors for Non-communicable Diseases in Bogor, West Java, Indonesia
Polymorphism UCP2 Gene in Predicting the Occurrence of Type 2 Diabetes Mellitus in Respondents Cohort Study of Risk Factors for Non-communicable Diseases in Bogor, West Java, Indonesia Open
Diabetes mellitus type 2 (DM) is a risk factor for other non-communicable diseases and is a problem, along with the increasing prevalence in Indonesia.One of the proteins involved in the occurrence of diabetes is UCP2, which is produced by…