Daojing Zhang
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View article: Porcine Epidemic Diarrhea Virus Is Inhibited by GS-441524 During an In Vitro Infection
Porcine Epidemic Diarrhea Virus Is Inhibited by GS-441524 During an In Vitro Infection Open
Porcine epidemic diarrhea virus (PEDV), the etiology of porcine epidemic diarrhea (PED), continues to impose severe economic burdens on pig farms in China. The continuous emergence of new variant strains makes it difficult for vaccinated s…
View article: Boosting ascomycin production through n-butanol addition in the fermentation process of<i>Streptomyces hygroscopicus var. ascomyceticus</i>ATCC 14891
Boosting ascomycin production through n-butanol addition in the fermentation process of<i>Streptomyces hygroscopicus var. ascomyceticus</i>ATCC 14891 Open
Ascomycin (FK520) is a macrolide antibiotic known for its immunosuppressive activities. In this study, we screened several short-chain alcohols to enhance titer of FK520 in Streptomyces hygroscopicus var. ascomyceticus ATCC 14891, with a p…
View article: Magnolol, a Neolignan-like Drug, Inhibits Porcine Epidemic Diarrhea Virus Replication in Cultured Cells
Magnolol, a Neolignan-like Drug, Inhibits Porcine Epidemic Diarrhea Virus Replication in Cultured Cells Open
Porcine epidemic diarrhea virus (PEDV) is a destructive pathogen that continues to adversely affect the swine industry worldwide due to a current lack of vaccines and drugs capable of effective disease control. In the present study, the ne…
View article: Bis-Benzylisoquinoline Alkaloids Inhibit Porcine Epidemic Diarrhea Virus In Vitro and In Vivo
Bis-Benzylisoquinoline Alkaloids Inhibit Porcine Epidemic Diarrhea Virus In Vitro and In Vivo Open
Porcine epidemic diarrhea virus (PEDV) belongs to the genus Alphacoronavirus of the family Coronaviridae that causes severe diarrhea and high mortality in neonatal suckling piglets. Currently, there is no effective medication against this …
View article: Pleiotropic regulation of a glucose-specific PTS in Clostridium acetobutylicum for high-efficient butanol production from corn stover without detoxification
Pleiotropic regulation of a glucose-specific PTS in Clostridium acetobutylicum for high-efficient butanol production from corn stover without detoxification Open
View article: The impact of Paenibacillus polymyxa HY96-2 luxS on biofilm formation and control of tomato bacterial wilt
The impact of Paenibacillus polymyxa HY96-2 luxS on biofilm formation and control of tomato bacterial wilt Open
View article: Complete Genome Sequence of Industrial Biocontrol Strain Paenibacillus polymyxa HY96-2 and Further Analysis of Its Biocontrol Mechanism
Complete Genome Sequence of Industrial Biocontrol Strain Paenibacillus polymyxa HY96-2 and Further Analysis of Its Biocontrol Mechanism Open
Paenibacillus polymyxa (formerly known as Bacillus polymyxa) has been extensively studied for agricultural applications as a plant-growth-promoting rhizobacterium and is also an important biocontrol agent. Our team has develo…
View article: Samholides, Swinholide-Related Metabolites from a Marine Cyanobacterium cf. <i>Phormidium</i> sp.
Samholides, Swinholide-Related Metabolites from a Marine Cyanobacterium cf. <i>Phormidium</i> sp. Open
Cancer cell cytotoxicity was used to guide the isolation of nine new swinholide-related compounds, named samholides A-I (1-9), from an American Samoan marine cyanobacterium cf. Phormidium sp. Their structures were determined by extensive a…
View article: Safe antifungal lipopeptides derived from Bacillus marinus B-9987 against grey mold caused by Botrytis cinerea
Safe antifungal lipopeptides derived from Bacillus marinus B-9987 against grey mold caused by Botrytis cinerea Open
Agricultural application studies, including field experiments and acute toxicity tests, were conducted for lipopeptides secreted by marine-derived Bacillus marinus B-9987. Benefiting from commercially available scaled-up lipopeptide purifi…
View article: Ghanamycins A and B, two novel γ-butyrolactones from marine-derived streptomyces ghanaensis TXC6-16
Ghanamycins A and B, two novel γ-butyrolactones from marine-derived streptomyces ghanaensis TXC6-16 Open
View article: Genomic Foundation of Starch-to-Lipid Switch in Oleaginous <i>Chlorella</i> spp.
Genomic Foundation of Starch-to-Lipid Switch in Oleaginous <i>Chlorella</i> spp. Open
The ability to rapidly switch the intracellular energy storage form from starch to lipids is an advantageous trait for microalgae feedstock. To probe this mechanism, we sequenced the 56.8-Mbp genome of Chlorella pyrenoidosa FACHB-9, an ind…