Daonan Chen
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View article: A CD36-based prediction model for sepsis-induced myocardial injury
A CD36-based prediction model for sepsis-induced myocardial injury Open
The prognosis of individuals with sepsis is closely associated with elevated CD36 levels. Elevated CD36 is identified as an independent risk factor for both SIMI and mortality in sepsis patients. The predictive model suggests that high CD3…
View article: Predictive value of the dynamics of absolute lymphocyte counts for 90-day mortality in ICU sepsis patients: a retrospective big data study
Predictive value of the dynamics of absolute lymphocyte counts for 90-day mortality in ICU sepsis patients: a retrospective big data study Open
Objectives The objective of the study was to assess the clinical predictive value of the dynamics of absolute lymphocyte count (ALC) for 90-day all-cause mortality in sepsis patients in intensive care unit (ICU). Design Retrospective cohor…
View article: [Related factors of euthyroid sick syndrome in patients with sepsis].
[Related factors of euthyroid sick syndrome in patients with sepsis]. Open
In this study, the incidence of ESS in sepsis patients was determined to be 28.2% with poor prognosis. The results showed that PCT, IL-6, CRP, SAA and APTT were independent risk factors for ESS in sepsis patients, while HDL-C was a protect…
View article: Recombinant human thrombopoietin in alleviating endothelial cell injury in sepsis
Recombinant human thrombopoietin in alleviating endothelial cell injury in sepsis Open
rhTPO alleviates endothelial injury and inflammatory indices in sepsis, and may regulate septic endothelial cell injury through the PI3K/Akt pathway.
View article: Awake prone positioning improves ventilation distribution in patients with acute respiratory failure: a prospective physiological study
Awake prone positioning improves ventilation distribution in patients with acute respiratory failure: a prospective physiological study Open
Background: Since the beginning of the coronavirus disease 2019 (COVID-19) pandemic, prone positioning has been widely applied for non-intubated, spontaneously breathing patients. Many clinical studies have shown that awake prone positioni…
View article: Application of Artificial Neural Network in Daily Prediction of Bleeding in ICU Patients Treated With Anti-Thrombotic Therapy
Application of Artificial Neural Network in Daily Prediction of Bleeding in ICU Patients Treated With Anti-Thrombotic Therapy Open
Objectives Anti-thrombotic therapy is the basis of thrombosis prevention and treatment. Bleeding is the main adverse event of anti-thrombosis. Existing laboratory indicators cannot accurately reflect the real-time coagulation function. It …
View article: Efficacy and safety of awake prone positioning in the treatment of non-intubated spontaneously breathing patients with COVID-19-related acute respiratory failure: A systematic review and meta-analysis
Efficacy and safety of awake prone positioning in the treatment of non-intubated spontaneously breathing patients with COVID-19-related acute respiratory failure: A systematic review and meta-analysis Open
APP was safe and reduced the need for intubation in patients with respiratory failure associated with COVID-19. However, it did not significantly reduce mortality in comparison to usual care without prone positioning.
View article: Statin Use is Associated with Reduced Mortality in Mechanically Ventilated Patients: A Retrospective Propensity-Matched Analysis of MIMIC-III Database
Statin Use is Associated with Reduced Mortality in Mechanically Ventilated Patients: A Retrospective Propensity-Matched Analysis of MIMIC-III Database Open
Background We sought to determine whether statin treatment has a protective effect on the outcome of critically ill patients on mechanical ventilation. Methods Patients who underwent mechanical ventilation were selected from the MIMIC-III …
View article: Paraquat is an agonist of STIM1 and Increases Intracellular Calcium Levels
Paraquat is an agonist of STIM1 and Increases Intracellular Calcium Levels Open
Paraquat (PQ) is an efficient herbicide utilized worldwide but leads to pulmonary fibrosis and high mortality with no antidote in mammals. PQ is well recognized to produce amounts of ROS, leading to epithelial-mesenchymal transition (EMT) …
View article: Statin Use Is Associated With Reduced Mortality On Mechanically Ventilated Patients : A Retrospective Propensity-Matched Analysis Of MIMIC-III Database
Statin Use Is Associated With Reduced Mortality On Mechanically Ventilated Patients : A Retrospective Propensity-Matched Analysis Of MIMIC-III Database Open
Background: The patients on mechanical ventilation were always critically ill and ventilation may cause injury and inflammatory disorders in the lungs of such patients. We sought to determine whether statin treatment has a protective effec…
View article: Statin Use Is Associated With Reduced Mortality On Mechanically Ventilated Patients:A Retrospective Propensity-Matched Analysis
Statin Use Is Associated With Reduced Mortality On Mechanically Ventilated Patients:A Retrospective Propensity-Matched Analysis Open
BackgroundThe patients on mechanical ventilation were always critically ill and ventilation may cause injury and inflammatory disorders in the lungs of such patients. We sought to determine whether statin treatment has a protective effect …
View article: Statin Use Is Associated With Reduced Mortality On Mechanically Ventilated Patients: A Retrospective Propensity-Matched Analysis Of MIMIC-III Database
Statin Use Is Associated With Reduced Mortality On Mechanically Ventilated Patients: A Retrospective Propensity-Matched Analysis Of MIMIC-III Database Open
Objective: Mechanical ventilation can cause injury and inflammatory disorders in the lungs of critically ill patients. We sought to determine whether statin treatment has a protective effect on the outcome of these patients. Methods: A ret…