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View article: Artificial Tyroserleutide Transporters for Synergistic Cancer Therapy
Artificial Tyroserleutide Transporters for Synergistic Cancer Therapy Open
Peptide transporters are integral membrane proteins responsible for the cellular uptake of dipeptides and tripeptides from the extracellular environment, which play pivotal roles in nutrient absorption, antigen presentation, and cellular s…
View article: Engineered Reactive Oxygen Species (ROS)‐Responsive Artificial H<sup>+</sup>/Cl<sup>−</sup> Ion Channels for Targeted Cancer Treatment
Engineered Reactive Oxygen Species (ROS)‐Responsive Artificial H<sup>+</sup>/Cl<sup>−</sup> Ion Channels for Targeted Cancer Treatment Open
Reactive oxygen species (ROS)‐responsive ion channels regulate the ion flow across the membranes in response to alterations in the cellular redox state, playing a crucial role in cellular adaptation to oxidative stress. Despite their signi…
View article: Concentration‐Driven Evolution of Adaptive Artificial Ion Channels or Nanopores with Specific Anticancer Activities
Concentration‐Driven Evolution of Adaptive Artificial Ion Channels or Nanopores with Specific Anticancer Activities Open
In nature, ceramides are a class of sphingolipids possessing a unique ability to self‐assemble into protein‐permeable channels with intriguing concentration‐dependent adaptive channel cavities. However, within the realm of artificial ion c…