Explanipedia

<span>MiR</span> ‐30d‐5p Regulates Bone Remodeling and Vessel Remodeling in Osteoporosis by Targeting <span>GRP78</span> Open

Jie Li, Ran Kang, Guang Li, Xinle Li, Daquan Liu , et al. · 2025

Osteoporosis is one of the major bone disorders that has a close relationship with osteogenesis and angiogenesis. MiRNA coordinates a cascade of anabolic and catabolic processes in bone homeostasis and dynamic vascularization. Here, the ro…

Effect of Biochar Types and Rates on SOC and Its Active Fractions in Tropical Farmlands of China Open

Mingwan Chen, Daquan Liu, Xujie Shao, Shoupeng Li, Xin Jin , et al. · 2024

To date, most studies have shown that biochar has great potential in carbon sequestration and reduction, as well as soil quality improvement. However, there is limited knowledge of its effect on soil organic carbon (SOC) fractions in tropi…

Effects of Different Forest Types on Stoichiometric Characteristics of Carbon, Nitrogen, and Phosphorus in Tropical Soils, China Open

Hong Liu, Jincun Qi, Daquan Liu, Jiwei Yang, Mingwan Chen , et al. · 2024

The stoichiometric characteristics of carbon (C), nitrogen (N), and phosphorus (P) in soil can directly reflect the level of soil fertility. In this study, a secondary forest, two kinds of plantation forests (Dacrycarpus imbricatus and Pin…

The Conversion of Tropical Natural Forests Alters Soil Carbon Fractions in Aggregates and Reduces Aggregate Stability Open

Daquan Liu, Mingwan Chen, Hongyuan Liu, Jincun Qi, Jiwei Yang , et al. · 2024

SUMO1 mediated salubrinal-treated the abnormal remodeling of the subchondral bone in osteoarthritis Open

Xinle Li, Jie Li, Qiu Wu, Daquan Liu, Hiroki Yokota , et al. · 2023

Background: Osteoarthritis (OA) is the most common joint disorder characterized by cartilage degradation and abnormal subchondral bone remodeling. As a post-translational modification, small ubiquitin-like modifiers (SUMOs) are involved in…

A static magnetic field enhances the repair of osteoarthritic cartilage by promoting the migration of stem cells and chondrogenesis Open

Yuting Sun, Yanwen Fang, Xinle Li, Jie Li, Daquan Liu , et al. · 2023

The findings in this study provided convincing evidence that SMF could enhance cartilage repair and improve OA symptoms, suggesting that SMF could have clinical value in the treatment of OA.

Retrospective case–control study on screening risk factors of antibiotic-associated encephalopathy in patients with chronic kidney disease Open

Hongling Wang, Daquan Liu · 2022

Objective The renal excretion function of patients with chronic kidney disease (CKD) is reduced, and the nervous system toxic reactions of antibiotics are prone to occur. The purpose of this study is to screen out some risk factors for pat…

Fault-tolerant motion planning for a hexapod robot with single-leg failure using a foot force control method Open

Bo You, Yaojin Fan, Daquan Liu · 2022

Hexapod robots are widely used for resource exploration, post-disaster rescue, and military equipment. They typically travel on rugged and complex roads. The robot itself has a high probability of failure owing to mechanical failure, drivi…

Deep Image-based Illumination Harmonization Open

Zhongyun Bao, Chengjiang Long, Gang Fu, Daquan Liu, Yuanzhen Li , et al. · 2021

Integrating a foreground object into a background scene with illumination harmonization is an important but challenging task in computer vision and augmented reality community. Existing methods mainly focus on foreground and background app…

Scene Inference for Object Illumination Editing. Open

Zhongyun Bao, Chengjiang Long, Gang Fu, Daquan Liu, Yuanzhen Li , et al. · 2021

The seamless illumination integration between a foreground object and a background scene is an important but challenging task in computer vision and augmented reality community. However, to our knowledge, there is no publicly available hig…

Mechanical loading attenuates breast cancer‐associated bone metastasis in obese mice by regulating the bone marrow microenvironment Open

Meng-lu Huang, Hong Liu, Lei Zhu, Xinle Li, Jie Li , et al. · 2021

Breast cancer, a common malignancy for women, preferentially metastasizes to bone and obesity elevates the chance of its progression. While mechanical loading can suppress obesity and tumor‐driven osteolysis, its effect on bone‐metastasize…

Instability Adjustment and Fault-tolerant Gait Design for Hexapod Robot Single Leg Failure Open

Bo You, Kunpeng Li, Jiayu Li, Daquan Liu · 2021

摘要: 对六足机器人在运动过程中,支撑腿发生单腿失效时的稳定性进行了分析,根据零力矩点法(ZMP)与力-角稳定锥法(FASM)结合的失稳判定流程给出一种基于实时运动平面解析求解方法的失稳倾翻调整策略;在CPG控制器分层建模的基础上设计一种自适应容错步态生成器,根据腿部负载的变化延长或缩短支撑相并且能够产生多种步态。采用ADAMS-Matlab联合仿真系统对六足机器人单腿失效倾翻调整策略和容错步态进行仿真,仿真结果表明:机器人发生失稳倾翻时能够在1 s内完成调整;自适应容错步…

Mechanical Loading Mitigates Osteoarthritis Symptoms by Regulating the Inflammatory Microenvironment Open

Weiwei Zhang, Xinle Li, Jie Li, Xiaoyu Wang, Daquan Liu , et al. · 2021

Phosphorylation of eIF2α signaling pathway attenuates obesity-induced non-alcoholic fatty liver disease in an ER stress and autophagy-dependent manner Open

Jie Li, Xinle Li, Daquan Liu, Shiqi Zhang, Nian Tan , et al. · 2020

Mechanical loading stimulates bone angiogenesis through enhancing type H vessel formation and downregulating exosomal miR‐214‐3p from bone marrow‐derived mesenchymal stem cells Open

Xuetong Wang, Xinle Li, Jie Li, Lidong Zhai, Daquan Liu , et al. · 2020

Exosomes are important transporters of miRNAs, which play varying roles in the healing of the bone fracture. Angiogenesis is one of such critical events in bone healing, and we previously reported the stimulatory effect of mechanical loadi…

Mechanical Loading Prevents Obesity-Associated Bone Loss by Maintaining the Balance between Adipocytes and Osteoblasts Open

Xinle Li, Jie Li, Daquan Liu, Keyu Wang, Hiroki Yokota , et al. · 2020

Background: Globally increasing obesity is closely linked to bone homeostasis. Maintaining the balance between differentiate of adipocytes and osteoblasts from bone marrow mesenchymal stem cells (BMSCs) is important for bone homeostasis. W…

Knee loading repairs osteoporotic osteoarthritis by relieving abnormal remodeling of subchondral bone via Wnt/β‐catenin signaling Open

Weiwei Zheng, Beibei Ding, Xinle Li, Daquan Liu, Hiroki Yokota , et al. · 2020

Osteoporotic osteoarthritis (OPOA) is a common bone disease mostly in the elderly, but the relationship between Osteoporotic (OP) and osteoarthritis (OA) is complex. It has been shown that knee loading can mitigate OA symptoms. However, it…

Effect of Rare-earth Variable-valence Element Eu doping on Thermoelectric Property of BiCuSeO Open

Huijun Kang, Xiaoying Zhang, Yanxia Wang, Jianbo Li, Xiong Yang , et al. · 2020

eIF2α signaling regulates autophagy of osteoblasts and the development of osteoclasts in OVX mice Open

Jie Li, Xinle Li, Daquan Liu, Kazunori Hamamura, Qiaoqiao Wan , et al. · 2019

Ankle loading ameliorates bone loss from breast cancer–associated bone metastasis Open

Shuang Yang, Hong Liu, Lei Zhu, Xinle Li, Daquan Liu , et al. · 2019

Breast cancer is a serious health problem that preferentially metastasizes to bone. We have previously shown that bone loss can be prevented by mechanical loading, but the efficacy of ankle loading for metastasis‐linked bone loss has not b…

Wnt3a involved in the mechanical loading on improvement of bone remodeling and angiogenesis in a postmenopausal osteoporosis mouse model Open

Xinle Li, Daquan Liu, Jie Li, Shuang Yang, Jinfeng Xu , et al. · 2019

Osteoporosis is a major health problem, making bones fragile and susceptible to fracture. Previous works showed that mechanical loading stimulated bone formation and accelerated fracture healing. Focusing on the role of Wnt3a (wingless/int…

Mechanical loading mitigates osteoarthritis symptoms by regulating endoplasmic reticulum stress and autophagy Open

Weiwei Zheng, Xinle Li, Daquan Liu, Jie Li, Shuang Yang , et al. · 2018

Osteoarthritis (OA) is a disease characterized by cartilage damage and abnormal remodeling of subchondral bone. Our previous study showed that in the early stage of OA, knee loading exerts protective effects by suppressing osteoclastogenes…

Activation of protein kinase C‑α/heme oxygenase‑1 signaling pathway improves mitochondrial dynamics in lipopolysaccharide‑activated NR8383 cells Open

Xiangyun Li, Yuan Zhang, Jianbo Yu, Rui Mu, Lili Wu , et al. · 2018

Mitochondrial function and morphology are dynamically regulated by fusion and fission. Heme oxygenase-1 (HO-1), which may be upregulated by protein kinase C-α (PKC-α), improves mitochondrial dynamics by controlling the balance between fusi…

Effects of knee loading on obesity‐related non‐alcoholic fatty liver disease in an ovariectomized mouse model with high‐fat diet Open

Nian Tan, Xinle Li, Lidong Zhai, Daquan Liu, Jie Li , et al. · 2018

Aim Hormonal and nutritional disorders are the main causes of obesity and non‐alcoholic fatty liver disease, especially in the elderly and in postmenopausal women. Although physical activity might alleviate these disorders, the elderly may…

eIF2α signaling regulates ischemic osteonecrosis through endoplasmic reticulum stress Open

Daquan Liu, Yunlong Zhang, Xinle Li, Jie Li, Shuang Yang , et al. · 2017

Trauma to an inguinal hernia resulting in bowel rupture: A case report and literature review Open

Daquan Liu, Lun Zhu, Mingkao Wang · 2017

Trauma directly to a known inguinal hernia is an uncommon, but a dangerous event, and the abnormal alterations of intestine in the hernial sac may be one of the major reasons for such event, so it is mandatory for the physician to explain …

Role of endoplasmic reticulum stress in disuse osteoporosis Open

Jie Li, Shuang Yang, Xinle Li, Daquan Liu, Zhaonan Wang , et al. · 2016

Effect of Heme Oxygenase-1 on Mitofusin-1 protein in LPS-induced ALI/ARDS in rats Open

Jianbo Yu, Ying Wang, Zhen Li, Shuan Dong, Dan Wang , et al. · 2016

Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is a common and important oxidative stress in the lung. Mitochondrial fusion responds to the normal morphology and function of cells and is finely regulated by mitochondria…

Knee loading inhibits osteoclast lineage in a mouse model of osteoarthritis Open

Xinle Li, Jing Yang, Daquan Liu, Jie Li, Kaijun Niu , et al. · 2016

Protective effect of hydrogen-rich medium against high glucose-induced apoptosis of Schwann cells in vitro Open

Yang Yu, Xiaoye Ma, Tao Yang, Bo Li, Keliang Xie , et al. · 2015

Diabetic peripheral neuropathy (DPN) is considered to be one of the most prevalent and life threatening microvascular diabetic complications. DPN affects up to 50% of patients with diabetes mellitus and there are currently no efficacious t…

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