Dara G. Ghahremani
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View article: ConvNeXt-Driven Detection of Alzheimer’s Disease: A Benchmark Study on Expert-Annotated AlzaSet MRI Dataset Across Anatomical Planes
ConvNeXt-Driven Detection of Alzheimer’s Disease: A Benchmark Study on Expert-Annotated AlzaSet MRI Dataset Across Anatomical Planes Open
Background: Alzheimer’s disease (AD) is a leading worldwide cause of cognitive impairment, necessitating accurate, inexpensive diagnostic tools to enable early recognition. Methods: In this study, we present a robust deep learning approach…
View article: ConvNeXt-Driven Detection of Alzheimer’s Disease: A Benchmark Study on Expert-Annotated AlzaSet MRI Dataset Across Anatomical Planes
ConvNeXt-Driven Detection of Alzheimer’s Disease: A Benchmark Study on Expert-Annotated AlzaSet MRI Dataset Across Anatomical Planes Open
Alzheimer’s disease (AD) is a leading worldwide cause of cognitive impairment, necessitating accurate, inexpensive diagnostic tools to enable early recognition. In this study, we present a robust deep learning approach for AD classificatio…
View article: Altered Neurobehavioral Reward Response Predicts Psychotic-Like Experiences in Youth Exposed to Cannabis Prenatally
Altered Neurobehavioral Reward Response Predicts Psychotic-Like Experiences in Youth Exposed to Cannabis Prenatally Open
View article: What does a dollar mean to you? utilizing intrinsic rewards within contingency management
What does a dollar mean to you? utilizing intrinsic rewards within contingency management Open
Substance Use Disorders (SUDs) pose a significant public health challenge. Medications used for treatment of SUDs are limited in their efficacy, particularly in cannabis and stimulant use disorders, and non-pharmacological interventions ha…
View article: Convergent Validity of Experimental Cognitive Tests in a Large Community Sample
Convergent Validity of Experimental Cognitive Tests in a Large Community Sample Open
Experimental cognitive tests are designed to measure particular cognitive domains, although evidence supporting test validity is often limited. The Consortium for Neuropsychiatric Phenomics test battery administered 23 experimental and tra…
View article: Altered neurobehavioral reward response predicts psychotic-like experiences in youth exposed to cannabis prenatally
Altered neurobehavioral reward response predicts psychotic-like experiences in youth exposed to cannabis prenatally Open
Importance Rates of prenatal cannabis exposure (PCE) are rising with increasingly permissive legislation regarding cannabis use, which may be a risk factor for psychosis. Disrupted reward-related neural circuitry may underlie this relation…
View article: Brain mGlu5 Is Linked to Cognition and Cigarette Smoking but Does Not Differ From Control in Early Abstinence From Chronic Methamphetamine Use
Brain mGlu5 Is Linked to Cognition and Cigarette Smoking but Does Not Differ From Control in Early Abstinence From Chronic Methamphetamine Use Open
Background The group-I metabotropic glutamate receptor subtype 5 (mGlu5) has been implicated in methamphetamine exposure in animals and in human cognition. Because people with methamphetamine use disorder (MUD) exhibit cognitive deficits, …
View article: Parameter Space and Potential for Biomarker Development in 25 Years of fMRI Drug Cue Reactivity
Parameter Space and Potential for Biomarker Development in 25 Years of fMRI Drug Cue Reactivity Open
Importance In the last 25 years, functional magnetic resonance imaging drug cue reactivity (FDCR) studies have characterized some core aspects in the neurobiology of drug addiction. However, no FDCR-derived biomarkers have been approved fo…
View article: Smoking, tobacco dependence, and neurometabolites in the dorsal anterior cingulate cortex
Smoking, tobacco dependence, and neurometabolites in the dorsal anterior cingulate cortex Open
Cigarette smoking has a major impact on global health and morbidity, and positron emission tomographic research has provided evidence for reduced inflammation in the human brain associated with cigarette smoking. Given the consequences of …
View article: Negative affect and craving during abstinence from smoking are both linked to default mode network connectivity
Negative affect and craving during abstinence from smoking are both linked to default mode network connectivity Open
View article: 0862 Effect of meditation and relaxation on physiological markers of stress and sleep
0862 Effect of meditation and relaxation on physiological markers of stress and sleep Open
Introduction Both breathing based meditation (interoceptive) and relaxation by improving blood circulation using heat and massage (exteroceptive) are known to reduce physiological stress. In this study, we determined the effect of stress-r…
View article: Editorial: Community series in neurobiological biomarkers for developing novel treatments of substance and non-substance addiction, volume II
Editorial: Community series in neurobiological biomarkers for developing novel treatments of substance and non-substance addiction, volume II Open
EDITORIAL article Front. Psychiatry, 13 April 2023Sec. Addictive Disorders Volume 14 - 2023 | https://doi.org/10.3389/fpsyt.2023.1134561
View article: Decomposing risky decision-making in methamphetamine use disorder: Behavioral updating and D2 dopamine receptors
Decomposing risky decision-making in methamphetamine use disorder: Behavioral updating and D2 dopamine receptors Open
View article: Nicotine dependence and insula subregions: functional connectivity and cue-induced activation
Nicotine dependence and insula subregions: functional connectivity and cue-induced activation Open
View article: Reduced neural functional connectivity during working memory performance in methamphetamine use disorder
Reduced neural functional connectivity during working memory performance in methamphetamine use disorder Open
These results suggest a decoupling in network dynamics that may underlie deficits in cognition during early abstinence in MUD patients.
View article: Cortical thickness and related depressive symptoms in early abstinence from chronic methamphetamine use
Cortical thickness and related depressive symptoms in early abstinence from chronic methamphetamine use Open
Methamphetamine use is surging globally as a cause of morbidity and mortality. Treatment is typically sought in early abstinence, when craving and depressive symptoms are intense, contributing to relapse and poor outcomes. To advance an un…
View article: A methodological checklist for fMRI drug cue reactivity studies: development and expert consensus
A methodological checklist for fMRI drug cue reactivity studies: development and expert consensus Open
View article: Editorial: Neurobiological Biomarkers for Developing Novel Treatments of Substance and Non-substance Addiction
Editorial: Neurobiological Biomarkers for Developing Novel Treatments of Substance and Non-substance Addiction Open
EDITORIAL article Front. Psychiatry, 20 December 2021 | https://doi.org/10.3389/fpsyt.2021.811032
View article: Neuroanatomical differences in the memory systems of intellectual giftedness and typical development
Neuroanatomical differences in the memory systems of intellectual giftedness and typical development Open
Introduction Studying neuro‐structural markers of intellectual giftedness (IG) will inform scientific understanding of the processes helping children excel academically. Methods Structural and diffusion‐weighted MRI was used to compare reg…
View article: Author response for "Neuroanatomical differences in the memory systems of intellectual giftedness and typical development"
Author response for "Neuroanatomical differences in the memory systems of intellectual giftedness and typical development" Open
View article: Age Influences Loss Aversion Through Effects on Posterior Cingulate Cortical Thickness
Age Influences Loss Aversion Through Effects on Posterior Cingulate Cortical Thickness Open
Decision-making strategies shift during normal aging and can profoundly affect wellbeing. Although overweighing losses compared to gains, termed “loss aversion,” plays an important role in choice selection, the age trajectory of this effec…
View article: Nicotine dependence and functional connectivity of insular cortex subregions
Nicotine dependence and functional connectivity of insular cortex subregions Open
The insular cortex has been identified as a promising target in brain-based therapies for Tobacco Use Disorder, and has three major sub-regions (ventral anterior, dorsal anterior, and posterior) that serve distinct functional networks. How…
View article: Functional connectivity of the anterior insula during withdrawal from cigarette smoking
Functional connectivity of the anterior insula during withdrawal from cigarette smoking Open
View article: Sex Differences in the Association of Cigarette Craving With Insula Structure
Sex Differences in the Association of Cigarette Craving With Insula Structure Open
Background Cigarette craving, which can negatively impact smoking cessation, is reportedly stronger in women than in men when they initiate abstinence from smoking. Identifying approaches to counteract craving in people of different sexes …
View article: Effects of oral contraceptive pills on mood and magnetic resonance imaging measures of prefrontal cortical thickness
Effects of oral contraceptive pills on mood and magnetic resonance imaging measures of prefrontal cortical thickness Open
View article: Diminished cortical response to risk and loss during risky decision making in alcohol use disorder
Diminished cortical response to risk and loss during risky decision making in alcohol use disorder Open
View article: A Methodological Checklist for fMRI Drug Cue Reactivity Studies: Development and Expert Consensus
A Methodological Checklist for fMRI Drug Cue Reactivity Studies: Development and Expert Consensus Open
Background Cue reactivity is one of the most frequently used paradigms in functional magnetic resonance imaging (fMRI) studies of substance use disorders (SUDs). While there have been promising results elucidating the neurocognitive mechan…
View article: A-157 How Important Is Sustained Attention in Reversal Learning and Visual Task Shifting Abilities: A Canonical Correlation Analysis in Adults
A-157 How Important Is Sustained Attention in Reversal Learning and Visual Task Shifting Abilities: A Canonical Correlation Analysis in Adults Open
Objective We used canonical correlation analysis (CCA) to examine the relationship between performance on cognitive neuroscience measures of sustained attention, deterministic reversal learning (DRLT), and visual task-shifting (VTS). We ev…
View article: Neural Basis of Smoking-Related Difficulties in Emotion Regulation
Neural Basis of Smoking-Related Difficulties in Emotion Regulation Open
Background Negative emotional states contribute to cigarette smoking, and difficulties in regulating these states can hinder smoking cessation. Understanding the neural bases of these difficulties in smokers may facilitate development of n…
View article: Resting-state functional connectivity in women with PMDD
Resting-state functional connectivity in women with PMDD Open