Daria Maria Monti
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View article: Novel Insights Into the Struggle Against Biofilm: The <i>Psy</i> <scp>Omp38</scp> Protein From the Antarctic Marine Bacterium <i>Psychrobacter</i> sp. <scp>TAE2020</scp>
Novel Insights Into the Struggle Against Biofilm: The <i>Psy</i> <span>Omp38</span> Protein From the Antarctic Marine Bacterium <i>Psychrobacter</i> sp. <span>TAE2020</span> Open
Antibiofilm molecules can enhance the effectiveness of antibiotics and prevent biofilm formation. Antarctic marine bacteria have been found to secrete antibiofilm molecules, likely as part of a strategy for competitive survival. The protei…
View article: Phytochemical Composition and Antioxidant Activity of a Viscum album Mother Tincture
Phytochemical Composition and Antioxidant Activity of a Viscum album Mother Tincture Open
In the last decades, extracts of Viscum album L., commonly known as European mistletoe, have attracted increasing interest for their immunomodulatory, anti-inflammatory and antioxidant activities. Nowadays, they are mainly used in compleme…
View article: Unlocking the Antiadipogenic Potential of Carotenoids From <i>Galdieria phlegrea</i>
Unlocking the Antiadipogenic Potential of Carotenoids From <i>Galdieria phlegrea</i> Open
Oxidative stress, a sedentary and inactive lifestyle, or a high‐fat diet are among the main causes responsible for the alteration of skin topography, a complex multifactorial disorder of the deeper layers of the skin, mainly caused by an i…
View article: Author Correction: Thymus algeriensis and Thymus fontanesii exert neuroprotective effect against chronic constriction injury-induced neuropathic pain in rats
Author Correction: Thymus algeriensis and Thymus fontanesii exert neuroprotective effect against chronic constriction injury-induced neuropathic pain in rats Open
View article: Elicitor‐mediated simultaneous accumulation of phloridzin and ursolic acid in Annurca apple peel‐derived calli
Elicitor‐mediated simultaneous accumulation of phloridzin and ursolic acid in Annurca apple peel‐derived calli Open
BACKGROUND Apple peel is rich in natural molecules, many exhibiting a significant bioactivity. In this study, our objective was to establish a novel callus line derived from the apple peel of the Italian local variety Annurca, known to acc…
View article: Pentadecanoic Acid-Releasing PDMS: Towards a New Material to Prevent S. epidermidis Biofilm Formation
Pentadecanoic Acid-Releasing PDMS: Towards a New Material to Prevent S. epidermidis Biofilm Formation Open
Microbial biofilm formation on medical devices paves the way for device-associated infections. Staphylococcus epidermidis is one of the most common strains involved in such infections as it is able to colonize numerous devices, such as int…
View article: Microalgae Flocculation: Assessment of Extraction Yields and Biological Activity
Microalgae Flocculation: Assessment of Extraction Yields and Biological Activity Open
Downstream costs represent one of the main obstacles to enabling microalgae to become widespread. The development of an economical, easily scaled-up strategy could reduce the overall process costs. Here, different flocculants were tested o…
View article: Unveiling the potential of Pseudococcomyxa simplex: a stepwise extraction for cosmetic applications
Unveiling the potential of Pseudococcomyxa simplex: a stepwise extraction for cosmetic applications Open
View article: Profiling of Petroselinum sativum (mill.) fuss phytoconstituents and assessment of their biocompatibility, antioxidant, anti-aging, wound healing, and antibacterial activities
Profiling of Petroselinum sativum (mill.) fuss phytoconstituents and assessment of their biocompatibility, antioxidant, anti-aging, wound healing, and antibacterial activities Open
Petroselinum sativum , known as parsley, is a fragrant herb that possesses a rich heritage of utilization in traditional medicinal practices. In this study, we annotated the phytocontents of the aqueous and ethanolic extracts of P. sativum…
View article: Chemical profiling and dermatological and anti-aging properties of Syzygium jambos L. (Alston): evidence from molecular docking, molecular dynamics, and in vitro experiments
Chemical profiling and dermatological and anti-aging properties of Syzygium jambos L. (Alston): evidence from molecular docking, molecular dynamics, and in vitro experiments Open
The phytoconstituents of the aqueous extract from Syzygium jambos L. (Alston) leaves were defined using HPLC-PDA-MS/MS and the antioxidant, anti-aging, antibacterial, and anti-biofilm activities of the extract were in silico and in vitro i…
View article: Use of yeast extract to elicit a pulp-derived callus cultures from Annurca apple and potentiate its biological activity
Use of yeast extract to elicit a pulp-derived callus cultures from Annurca apple and potentiate its biological activity Open
Today, plant cell cultures represent a valid alternative method to produce secondary metabolites. Here, we developed a protocol to obtain callus cultures from the pulp of the Italian apple variety, named Annurca. To increase the accumulati…
View article: Aqueous Extracts from Hemp Seeds as a New Weapon against Staphylococcus epidermidis Biofilms
Aqueous Extracts from Hemp Seeds as a New Weapon against Staphylococcus epidermidis Biofilms Open
This study investigated the antibiofilm activity of water-soluble extracts obtained under different pH conditions from Cannabis sativa seeds and from previously defatted seeds. The chemical composition of the extracts, determined through G…
View article: Steric hindrance and charge influence on the cytotoxic activity and protein binding properties of diruthenium complexes
Steric hindrance and charge influence on the cytotoxic activity and protein binding properties of diruthenium complexes Open
Paddlewheel diruthenium complexes are being used as metal-based drugs. It has been proposed that their charge and steric properties determine their selectivity towards proteins. Here, we explore these parameters using the first water-solub…
View article: The hydrophilic extract from a new tomato genotype (named DHO) kills cancer cell lines through the modulation of the DNA damage response induced by Campthotecin treatment
The hydrophilic extract from a new tomato genotype (named DHO) kills cancer cell lines through the modulation of the DNA damage response induced by Campthotecin treatment Open
Introduction DNA double-strand breaks are the most toxic lesions repaired through the non-homologous and joining (NHEJ) or the homologous recombination (HR), which is dependent on the generation of single-strand tails, by the DNA end resec…
View article: An Alternative Exploitation of Synechocystis sp. PCC6803: A Cascade Approach for the Recovery of High Added-Value Products
An Alternative Exploitation of Synechocystis sp. PCC6803: A Cascade Approach for the Recovery of High Added-Value Products Open
Microalgal biomass represents a very interesting biological feedstock to be converted into several high-value products in a biorefinery approach. In this study, the cyanobacterium Synechocystis sp. PCC6803 was used to obtain different clas…
View article: Biosynthesis of Silver Nanoparticles Using Salvia pratensis L. Aerial Part and Root Extracts: Bioactivity, Biocompatibility, and Catalytic Potential
Biosynthesis of Silver Nanoparticles Using Salvia pratensis L. Aerial Part and Root Extracts: Bioactivity, Biocompatibility, and Catalytic Potential Open
The aim of this research was the synthesis of silver nanoparticles (SPA- and SPR-AgNPs) using the aqueous extracts of the aerial (SPA) and the root (SPR) parts of the plant Salvia pratensis L., their characterization, reaction condition op…
View article: Shedding Light on the Hidden Benefit of Porphyridium cruentum Culture
Shedding Light on the Hidden Benefit of Porphyridium cruentum Culture Open
Microalgae can represent a reliable source of natural compounds with different activities. Here, we evaluated the antioxidant and anti-inflammatory activity of sulfated exopolysaccharides (s-EPSs) and phycoerythrin (PE), two molecules natu…
View article: Impact of Hydrophobic Chains in Five-Coordinate Glucoconjugate Pt(II) Anticancer Agents
Impact of Hydrophobic Chains in Five-Coordinate Glucoconjugate Pt(II) Anticancer Agents Open
This study describes new platinum(II) cationic five-coordinate complexes (1-R,R’) of the formula [PtR(NHC)(dmphen)(ethene)]CF3SO3 (dmphen = 2,9-dimethyl-1,10-phenanthroline), containing in their axial positions an alkyl group R (methyl or …
View article: The Apparent Organ-Specificity of Amyloidogenic ApoA-I Variants Is Linked to Tissue-Specific Extracellular Matrix Components
The Apparent Organ-Specificity of Amyloidogenic ApoA-I Variants Is Linked to Tissue-Specific Extracellular Matrix Components Open
Apolipoprotein A-I (ApoA-I) amyloidosis is a rare protein misfolding disease where fibrils of the N-terminal domain of the protein accumulate in several organs, leading to their failure. Although ApoA-I amyloidosis is systemic, the differe…
View article: Inside out <i>Porphyridium cruentum</i>: Beyond the Conventional Biorefinery Concept
Inside out <i>Porphyridium cruentum</i>: Beyond the Conventional Biorefinery Concept Open
Here, an unprecedented biorefinery approach has been designed to recover high-added value bioproducts starting from the culture ofPorphyridium cruentum. This unicellular marine red alga can secrete and accumulate high-value compound…
View article: Evaluation of Auranofin Loading within Ferritin Nanocages
Evaluation of Auranofin Loading within Ferritin Nanocages Open
Auranofin (AF), a gold(I) compound that is currently used for the treatment of rheumatoid arthritis and is in clinical trials for its promising anticancer activity, was encapsulated within the human H-chain and the horse spleen ferritin na…
View article: Chestnut Wood Mud as a Source of Ellagic Acid for Dermo-Cosmetic Applications
Chestnut Wood Mud as a Source of Ellagic Acid for Dermo-Cosmetic Applications Open
Ellagic acid (EA) has long been recognized as a very active antioxidant, anti-inflammatory, and antimicrobial agent. However, its low bioavailability has often hampered its applications in health-related fields. Here, we report a phospholi…
View article: CCDC 2151285: Experimental Crystal Structure Determination
CCDC 2151285: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Protein-Based Delivery Systems for Anticancer Metallodrugs: Structure and Biological Activity of the Oxaliplatin/β-Lactoglobulin Adduct
Protein-Based Delivery Systems for Anticancer Metallodrugs: Structure and Biological Activity of the Oxaliplatin/β-Lactoglobulin Adduct Open
β-lactoglobulin is the major component of whey. Here, the adduct formed upon the reaction of the protein with oxaliplatin (OXA) has been prepared, structurally characterized by X-ray crystallography and electrospray ionization–mass spectro…
View article: Autophagy Alteration in ApoA-I Related Systemic Amyloidosis
Autophagy Alteration in ApoA-I Related Systemic Amyloidosis Open
Amyloidoses are characterized by the accumulation and aggregation of misfolded proteins into fibrils in different organs, leading to cell death and consequent organ dysfunction. The specific substitution of Leu 75 for Pro in Apolipoprotein…
View article: Halo complexes of gold(<scp>i</scp>) containing glycoconjugate carbene ligands: synthesis, characterization, cytotoxicity and interaction with proteins and DNA model systems
Halo complexes of gold(<span>i</span>) containing glycoconjugate carbene ligands: synthesis, characterization, cytotoxicity and interaction with proteins and DNA model systems Open
New neutral Au( i ) glycoconjugate carbene complexes show stability in aqueous solutions and interact with both DNA and protein model systems. Cytotoxicity studies demonstrate that the activity depends on the halide ancillary ligand.
View article: Switchable Solvent Selective Extraction of Hydrophobic Antioxidants from <i>Synechococcus bigranulatus</i>
Switchable Solvent Selective Extraction of Hydrophobic Antioxidants from <i>Synechococcus bigranulatus</i> Open
Hydrophobic molecules, in particular, carotenoids, have been directly extracted from Synechococcus bigranulatus ACUF680 by means of secondary amine switchable solvent N-ethylbutylamine (EBA) without any other pretreatment. EBA was able to …
View article: Correction of oxidative stress enhances enzyme replacement therapy in Pompe disease
Correction of oxidative stress enhances enzyme replacement therapy in Pompe disease Open
View article: Square-Planar vs. Trigonal Bipyramidal Geometry in Pt(II) Complexes Containing Triazole-Based Glucose Ligands as Potential Anticancer Agents
Square-Planar vs. Trigonal Bipyramidal Geometry in Pt(II) Complexes Containing Triazole-Based Glucose Ligands as Potential Anticancer Agents Open
This article describes the synthesis, characterization, and biological activity of novel square-planar cationic platinum(II) complexes containing glucoconjugated triazole ligands and a comparison with the results obtained from the correspo…
View article: Towards the Development of Antioxidant Cerium Oxide Nanoparticles for Biomedical Applications: Controlling the Properties by Tuning Synthesis Conditions
Towards the Development of Antioxidant Cerium Oxide Nanoparticles for Biomedical Applications: Controlling the Properties by Tuning Synthesis Conditions Open
In this work CeO2 nanoparticles (CeO2-NPs) were synthesized through the thermal decomposition of Ce(NO3)3·6H2O, using as capping agents either octylamine or oleylamine, to evaluate the effect of alkyl chain length, an issue at 150 °C, in t…