Explanipedia

<b>CORRELATION OF Hba1C LEVELS WITH RETINAL CHANGES IN PATIENTS WITH DIABETIC RETINOPATHY</b> Open

Dr Khan, Dr Umer Mushtaq, Dr Fajar Khalid, Dr Syed Ahmed Shahzain Hussain Dr. Chaudhry Shahzad Aslam, Shema Tariq , et al. · 2025

Background: Diabetic retinopathy (DR) is a leading cause of vision loss among individuals with diabetes mellitus. Glycated hemoglobin (HbA1c) is widely used as a biomarker for long-term glycemic control. Objective: This study aimed to eval…

Pre-treatment untargeted cerebrospinal fluid metabolomic profiling in tuberculous meningitis uncovers pathways associated with mortality Open

Thanh Hoang Nhat Le, Kirsten C J van Abeelen, Edwin Ardiansyah, Julián Ávila-Pacheco, Sofiati Dian , et al. · 2025

National Institute of Health; Wellcome Trust, UK.

EVALUATION OF GRA6 AS GENETIC MARKER FOR DETERMINING <i>TOXOPLASMA GONDII</i> GENOTYPE IN THE CEREBROSPINAL FLUID OF HIV/AIDS PATIENTS WITH TOXOPLASMIC ENCEPHALITIS. Open

Harminarti Nora, Sari Ika Puspa, Artama Wayan Tunas, Darma Imran, Kurniawan Agnes · 2025

GRA6 had been proven effective as a genetic marker for the identification of T. gondii genotype among HIV/AIDS patients with Toxoplasmic encephalitis. However, the evaluation of GRA6 showed more effectiveness in cultured cells compa…

Assessing the Medical Student’s Knowledge and Awareness of MONA Protocol and Oxygen Therapy in Acute Myocardial Infarction: A Cross-Sectional Study Open

Ghania Shehzad Alam Qureshi, Madjda Khemissa, Ganna Amr Ibrahim Sabri, Darma Imran, Dr Mohamed Anas Patni , et al. · 2024

Introduction: The mnemonic "MONA," comprising Morphine, Oxygen, Nitroglycerin, and Aspirin, has been a cornerstone in the initial treatment of Acute Myocardial Infarction (AMI) and has been ingrained in the education of medical students fo…

Advancing the chemotherapy of tuberculous meningitis: a consensus view Open

Sean Wasserman, Joseph Donovan, Evelyne Kestelyn, James A Watson, R.E. Aarnoutse , et al. · 2024

Pendekatan Diagnosis dan Tata Laksana Multipel Sklerosis Open

Agustinus Sutanto, Putri Widya Andini, Kartika Maharani, Darma Imran, Riwanti Estiasari · 2024

Dilaporkan tiga kasus pada pasien dewasa muda dengan gejala neurologis tipikal dan atipikal yang didukung oleh temuan pencitraan otak dan spinal, serta analisis cairan serebrospinal (CSS) yang sesuai untuk diagnosis multipel sklerosis (MS)…

Multidisciplinary re-evaluation of neuropsychiatric events to confirm the neuropsychiatric lupus diagnosis at an Indonesian tertiary hospital Open

Riwanti Estiasari, Syairah Banu, Alvina Widhani, Fitri Octaviana, Kartika Maharani , et al. · 2024

Objective Neuropsychiatric SLE (NPSLE) has a broad spectrum and to date, there is no gold-standard biomarker. The diagnosis relies on clinical assessment, supporting examinations and exclusion of other possible aetiologies. One method that…

Clinical presentation, management, and outcome of suspected central nervous system infections in Indonesia: a prospective cohort study Open

Kartika Maharani, Sofiati Dian, Ahmad Rizal Ganiem, Darma Imran, Riwanti Estiasari , et al. · 2024

Background Little is known about the etiology, clinical presentation, management, and outcome of central nervous system (CNS) infections in Indonesia, a country with a high burden of infectious diseases and a rising prevalence of HIV. Meth…

Tuberculous meningitis patient pathways and delays to diagnosis in Indonesia: a retrospective cohort study Open

Gerine Nijman, Darma Imran, Sofiati Dian, Ahmad Rizal Ganiem, Riwanti Estiasari , et al. · 2023

Introduction Delays in diagnosis and treatment contribute to high mortality of tuberculous meningitis (TBM). We studied TBM patient pathways including delays to diagnosis, and their alignment with available diagnostic services in Indonesia…

Adjunctive Dexamethasone for Tuberculous Meningitis in HIV-Positive Adults Open

Joseph Donovan, Nguyen Duc Bang, Darma Imran, Ho D.T. Nghia, Erlina Burhan , et al. · 2023

Among HIV-positive adults with tuberculous meningitis, adjunctive dexamethasone, as compared with placebo, did not confer a benefit with respect to survival or any secondary end point. (Funded by the Wellcome Trust; ACT HIV ClinicalTrials.…

Prognostic identifier of cerebrovascular complications in tuberculous meningitis: Meta-analysis Open

Julianto Tomidy, Gede Bagus Yoga Satriadinatha, Filbert Kurnia Liwang, Kartika Maharani, Darma Imran , et al. · 2023

Characteristics Of Ocular Fundus In Brain Infections At Cipto Mangunkusumo Hospital Jakarta Open

Maria Jheny Fulgensia Purba, Pradita Sari, Septiana Andri Wardana, Ni Nengah Rida Ariarini, Kartika Maharani , et al. · 2023

Background: Brain infections (BI) may cause optic nerve abnormalities. Awareness on optic nerve abnormalities will be useful in assisting further management. The characteristics of the ocular fundus (fundus) in BI have not been widely stud…

Tryptophan metabolism determines outcome in tuberculous meningitis: a targeted metabolomic analysis Open

Edwin Ardiansyah, Julián Ávila-Pacheco, Le Thanh Hoang Nhat, Sofiati Dian, Dao Nguyen Vinh , et al. · 2023

Background: Cellular metabolism is critical for the host immune function against pathogens, and metabolomic analysis may help understand the characteristic immunopathology of tuberculosis. We performed targeted metabolomic analyses in a la…

Author response: Tryptophan metabolism determines outcome in tuberculous meningitis: a targeted metabolomic analysis Open

Edwin Ardiansyah, Julián Ávila-Pacheco, Le Thanh Hoang Nhat, Sofiati Dian, Dao Nguyen Vinh , et al. · 2023

Cryptococcal Meningitis and Clinical Outcomes in Persons With Human Immunodeficiency Virus: A Global View Open

Anna K. Person, Brenda Crabtree‐Ramírez, Ahra Kim, Valdiléa G. Veloso, Fernanda Maruri , et al. · 2023

Background Cryptococcal meningitis (CM) is a major cause of morbidity and mortality in persons with human immunodeficiency virus (HIV; PWH). Little is known about CM outcomes and availability of diagnostic and treatment modalities globally…

Tryptophan metabolism determines outcome in tuberculous meningitis: a targeted metabolomic analysis Open

Edwin Ardiansyah, Julián Avila Pacheco, Le Thanh Hoang Nhat, Sofiati Dian, Dao Nguyen Vinh , et al. · 2023

Background Cellular metabolism is critical for the host immune function against pathogens, and metabolomic analysis may help understand the characteristic immunopathology of tuberculosis. We performed targeted metabolomic analyses in a lar…

Encephalomyelitis associated with coronavirus disease 2019: a case report Open

Riwanti Estiasari, Kartika Maharani, Fitri Octaviana, Anyelir Nielya Mutiara Putri, Syifa Laila Ramadhan , et al. · 2022

Prognostic Identifier of Cerebrovascular Complications in Tuberculous Meningitis: Meta-Analysis Open

Julianto Tomidy, Gede Bagus Yoga Satriadinatha, Filbert Kurnia Liwang, Kartika Maharani, Darma Imran , et al. · 2022

Purpose: This study aimed to find predictors of stroke in patients with tuberculous meningitis.Methods: This systematic review and meta-analysis were done using literature searches through online databases up to April 30th, 2022. Three ind…

Molecular Identification of Cryptococcus neoformans Isolates from House Environments of HIV-Infected Patients in an Urban Area, Indonesia: A First Report Open

Machrumnizar Machrumnizar, Robiatul Adawıyah, Tjahjani Natriana, Darma Imran, Mohammad Muslim , et al. · 2022

Cryptococcus neoformans isolates were previously obtained from pigeon droppings in Jakarta. This study aimed to determine another source of infection and describe the supporting niche of the fungus. The occurrence of C. neoformans was eval…

Neurological Disease Associated with Chikungunya in Indonesia Open

Khin Saw Aye Myint, Arthur H.P. Mawuntu, Sotianingsih Haryanto, Darma Imran, Sofiati Dian , et al. · 2022

Chikungunya virus (CHIKV) is recognized but rarely considered as a cause of central nervous system infection in endemic areas. A total of 244 patients with acute meningoencephalitis in Indonesia were retrospectively tested to identify whet…

Comparison of Microscopic Decompression and Biportal Endoscopic Spinal Surgery in the Treatment of Lumbar Canal Stenosis and Herniated Disc: A One-year Follow-up Open

Didik Librianto, Fachrisal Ipang, Ifran Saleh, Widyastuti Srie Utami, Dina Aprilya , et al. · 2022

Backgrounds. Microscopic decompression (MD) has been widely used as an alternative to open decompression. Lately, biportal endoscopic spinal surgery (BESS) - a new approach in minimal-invasive spinal surgery – has also been used with good …

Neuroophthalmic manifestation of cortical brain tumor in Dr. Cipto Mangunkusumo General Hospital Indonesia Open

Novita Ayu Sinthia, Tiara Aninditha, Ni Nengah Rida Ariarini, Freddy Sitorus, Darma Imran , et al. · 2022

Knowledge, Attitude, Behavior, and Socioeconomic Conditions of People Living with HIV in Indonesia During the COVID-19 Pandemic: A Cross-Sectional Study Open

Teguh Harjono Karjadi, Suzy Maria, Evy Yunihastuti, Alvina Widhani, Nia Kurniati , et al. · 2021

This study provides an overview of what PLWH are experiencing, which will allow for policy-making that can help them continue their treatment with consideration of the possibility of having to live a "new normal" future.

Knowledge, Attitude, Behavior, and Socioeconomic Conditions of People Living with HIV in Indonesia During the COVID-19 Pandemic: A Cross-Sectional Study Open

Karjadi TH, Susana M. Silva, Evy Yunihastuti, Alvina Widhani, Nia Kurniati , et al. · 2021

Teguh Harjono Karjadi,1,2 Suzy Maria,1,2 Evy Yunihastuti,1,2 Alvina Widhani,1,2 Nia Kurniati,1,3 Darma Imran1,4 1Integrated HIV Center, Dr. Cipto Mangunkusumo General Hospital, Central Jakarta, DKI Jakarta, Indonesia; 2Allergy and Clinical…

The risk of coronavirus disease (COVID-19) transmission to health workers in the neurology medical service at Dr. Cipto Mangunkusumo National Hospital, Jakarta Open

Ahmad Yanuar Safri, Riwanti Estiasari, Kartika Maharani, Astri Budikayanti, Ediva Pradiptaloka , et al. · 2021

An Extremely Rare Case of Upper Thoracic Salmonella Infection Open

Didik Librianto, Suhendro Suwarto, Darma Imran, Hikmat Pramukti, Ifran Saleh , et al. · 2021

Salmonella infection must be considered to be one of possible etiological agents in patients with suggestive spondylitis in emerging countries, especially in those with comorbidities.

Evaluation of Retinal Structure and Optic Nerve Function Changes in Multiple Sclerosis: Longitudinal Study with 1-Year Follow-Up Open

Riwanti Estiasari, Adisresti Diwyacitta, Muhammad Sidik, Ni Nengah Rida Ariarini, Freddy Sitorus , et al. · 2021

Background. Multiple sclerosis (MS) is an autoimmune disease characterized by inflammation and demyelination of the central nervous system which often involves the optic nerve even though only 20% of the patients experience optic neuritis …

Touch Biopsy: A Simple and Rapid Method for the Diagnosis of Systemic Mycoses with Skin Dissemination in HIV-Infected Patients Open

Retno Wahyuningsih, Robiatul Adawıyah, Aida S. D. Hoemardani, Ridhawati Sjam, Evy Yunihastuti , et al. · 2021

Systemic fungal infection can disseminate to the skin and require prompt treatment, making early diagnosis very important. This study describes the use of a simple, quick touch biopsy method for the diagnosis of invasive mycoses in patient…

Clinical and mycologycal characteristics of AIDS patients with meningeal cryptococcosis in Jakarta, Indonesia Open

Robiatul Adawıyah, Darma Imran, Anna Rozaliyani, Riwanti Estiasari, Kartika Maharani , et al. · 2020

Background: Meningeal cryptococcosis is an opportunistic infection that occurs in HIV-infected patients. The main cause of cryptococcosis in the world is Cryptococcus neoformans, as well as in Indonesia. The clinical outcome of cryptococco…

EPID-32. SURVIVAL OF INTRACRANIAL TUMOR IN CIPTO MANGUNKUSUMO GENERAL HOSPITAL Open

Tiara Aninditha, Putra Pratama, Jonathan Odilo, Henry Riyanto Sofyan, Darma Imran , et al. · 2020

INTRODUCTION Intracranial tumor is a debilitating health burden that cause sever disability. The incidence rate for intracranial tumor is 4.63 per 100,000 populations. Through the development of diagnostic and therapeutic modalities, the s…

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