Darrell R. Abernethy
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View article: Issue Information
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Aims and Scope: For more than 50 years, clinical pharmacologists, clinical and pharmaceutical researchers, drug development specialists, physicians, nurses, and other medical professionals have relied on The Journal of Clinical Pharmacolog…
View article: Improving Therapeutics to Better Care for Older Adults and the Young: Report From the American College of Clinical Pharmacology Workshop
Improving Therapeutics to Better Care for Older Adults and the Young: Report From the American College of Clinical Pharmacology Workshop Open
About 50 years ago, Harry Shirkey MD, a pediatrician coined the term that infants and children are “therapeutic or pharmaceutical orphans.”1 This is because many of the drugs approved in the 1960s carry an “orphaning” clause, such as “not …
View article: Use of Biomedical Ontologies for Integration of Biological Knowledge for Learning and Prediction of Adverse Drug Reactions
Use of Biomedical Ontologies for Integration of Biological Knowledge for Learning and Prediction of Adverse Drug Reactions Open
Drug-induced toxicity is a major public health concern that leads to patient morbidity and mortality. To address this problem, the Food and Drug Administration is working on the PredicTox initiative, a pilot research program on tyrosine ki…
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Aims and Scope: Clinical Pharmacology in Drug Development is an international, peer-reviewed, online publication focused on publishing high-quality clinical pharmacology studies in drug development which are primarily (but not exclusively)…
View article: Issue Information
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Aims and Scope: For more than 50 years, clinical pharmacologists, clinical and pharmaceutical researchers, drug development specialists, physicians, nurses, and other medical professionals have relied on The Journal of Clinical Pharmacolog…
View article: In Memoriam: David A. Flockhart, 1952–2015
In Memoriam: David A. Flockhart, 1952–2015 Open
We lost David Flockhart on Thanksgiving Day, 2015. He was 63 years old, and had battled cancer for more than a year. David Flockhart was a pioneer and innovator in the field of pharmacogenetics. His conceptual contributions to pharmacogeno…
View article: In Memoriam: David A. Flockhart, 1952–2015
In Memoriam: David A. Flockhart, 1952–2015 Open
We lost David Flockhart on Thanksgiving Day, 2015. He was 63 years old, and had battled cancer for more than a year. David Flockhart was a pioneer and innovator in the field of pharmacogenetics. His conceptual contributions to pharmacogeno…
View article: Bidirectional interactions between indomethacin and the murine intestinal microbiota
Bidirectional interactions between indomethacin and the murine intestinal microbiota Open
The vertebrate gut microbiota have been implicated in the metabolism of xenobiotic compounds, motivating studies of microbe-driven metabolism of clinically important drugs. Here, we studied interactions between the microbiota and indometha…
View article: Author response: Bidirectional interactions between indomethacin and the murine intestinal microbiota
Author response: Bidirectional interactions between indomethacin and the murine intestinal microbiota Open
Article Figures and data Abstract eLife digest Introduction Results Discussion Materials and methods Data availability References Decision letter Author response Article and author information Metrics Abstract The vertebrate gut microbiota…
View article: Replication – why we need to publish our findings
Replication – why we need to publish our findings Open
The pharmacology research sector is changing to accommodate a need for greater transparency and better standards. The themed articles contained herein explain how Pharmacology Research and Perspectives ( PR &P) has responded to this agenda…
View article: Revision of instructions to authors for pharmacology research and perspectives: enhancing the quality and transparency of published work
Revision of instructions to authors for pharmacology research and perspectives: enhancing the quality and transparency of published work Open
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