Darryl Rolfson
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View article: COVID-19–Associated Outcomes of Critical Illness in Patients with Frailty: a Cohort Study
COVID-19–Associated Outcomes of Critical Illness in Patients with Frailty: a Cohort Study Open
Background Pre-admission frailty has been associated with higher hospital mortality in patients with critical illness. We aimed to measure the prevalence of frailty and its associated outcomes in patients with COVID-19 critical illness. Me…
View article: Edmonton Frail Scale predicts mortality in older patients with cancer undergoing radiotherapy—A prospective observational study
Edmonton Frail Scale predicts mortality in older patients with cancer undergoing radiotherapy—A prospective observational study Open
Background Several screening tools are developed to identify frailty in the increasing number of older patients with cancer. Edmonton Frail Scale (EFS) performs well in geriatric settings but is less studied in oncology. We aimed to invest…
View article: Designing an International Faculty Development Program in Medical Education: Capacity and Partnership
Designing an International Faculty Development Program in Medical Education: Capacity and Partnership Open
Providing international medical educators with opportunities for faculty development has become a favorable moment for capacity building and the creation of partnerships with universities around the world. It has also become a social respo…
View article: Cognitive Trajectories in Older Patients with Cancer Undergoing Radiotherapy—A Prospective Observational Study
Cognitive Trajectories in Older Patients with Cancer Undergoing Radiotherapy—A Prospective Observational Study Open
Cognitive function can be affected by cancer and/or its treatment, and older patients are at a particular risk. In a prospective observational study including patients ≥65 years referred for radiotherapy (RT), we aimed to investigate the a…
View article: The frailty, outcomes, recovery and care steps of critically ill patients (FORECAST) study: pilot study results
The frailty, outcomes, recovery and care steps of critically ill patients (FORECAST) study: pilot study results Open
Introduction Frailty is common in critically ill patients and is associated with increased morbidity and mortality. There remains uncertainty as to the optimal method/timing of frailty assessment and the impact of care processes and advers…
View article: An international Delphi consensus process to determine a common data element and core outcome set for frailty: FOCUS (The Frailty Outcomes Consensus Project)
An international Delphi consensus process to determine a common data element and core outcome set for frailty: FOCUS (The Frailty Outcomes Consensus Project) Open
Background Despite increased recognition of frailty and its importance, high quality evidence to guide decision-making is lacking. There has been variation in reported data elements and outcomes which makes it challenging to interpret resu…
View article: Association between preoperative frailty and outcomes among adults undergoing cardiac surgery: a prospective cohort study
Association between preoperative frailty and outcomes among adults undergoing cardiac surgery: a prospective cohort study Open
Preoperative frailty was present in 10% of patients and was associated with a higher risk of morbidity and greater health services use. Preoperative frailty has important implications for the postoperative clinical course and resource util…
View article: Customizing a Program for Older Adults Living with Frailty in Primary Care
Customizing a Program for Older Adults Living with Frailty in Primary Care Open
Coordination of primary care is essential to improving care delivery within health systems, especially for older adults with increased health/social needs. A program jointly funded by the Canadian Foundation for Healthcare Improvement and …
View article: Sex-specific prevalence and outcomes of frailty in critically ill patients
Sex-specific prevalence and outcomes of frailty in critically ill patients Open
Background The prevalence of frailty, an important risk factor for short- and long-term outcomes in hospitalized adults, differs by sex. Studies in critically ill adults have also found differences in mortality and organ support rates in m…
View article: The Impact of Preoperative Frailty on the Clinical and Cost Outcomes of Adult Cardiac Surgery in Alberta, Canada: A Cohort Study
The Impact of Preoperative Frailty on the Clinical and Cost Outcomes of Adult Cardiac Surgery in Alberta, Canada: A Cohort Study Open
Frailty screening identified a population with greater impairment in quality-of-life and greater healthcare costs. Costs attributable to frailty represent opportunity costs that should be considered in future cardiac surgical services plan…
View article: Interrater Reliability of the Clinical Frailty Scale by Geriatrician and Intensivist in Patients Admitted to the Intensive Care Unit
Interrater Reliability of the Clinical Frailty Scale by Geriatrician and Intensivist in Patients Admitted to the Intensive Care Unit Open
Background The Clinical Frailty Scale (CFS) is a commonly used frailty measure in intensive care unit (ICU) settings. We are interested in the test characteristics, especially interrater reliability, of the CFS in ICU by comparing the sco…
View article: <p>Utilization of computerized clinical decision support for potentially inappropriate medications</p>
Utilization of computerized clinical decision support for potentially inappropriate medications Open
Background: Electronic medical record (EMR) alerts may inform point of care decisions, including the decision to prescribe potentially inappropriate medications (PIM) identified in the Beers criteria. EMR alerts may not be considered relev…
View article: Successful Aging and Frailty: A Systematic Review
Successful Aging and Frailty: A Systematic Review Open
The terms successful aging (SA) and frailty appear to have much in common, both in terms of overlapping constructs and common challenges with consensus and operationalization. The aim of this review is to summarize existing literature that…
View article: Implementing Frailty Measures in the Canadian Healthcare System
Implementing Frailty Measures in the Canadian Healthcare System Open
Canadian healthcare is changing to include individuals living with frailty, but frailty must be better operationalized and better framed by sound data standards and policy. Frailty results from deficit accumulation in multiple body systems…
View article: Identification and management of frailty in the primary care setting
Identification and management of frailty in the primary care setting Open
[See related article at [www.cmaj.ca/lookup/doi/10.1503/cmaj.181151][2]][2] KEY POINTS Frailty is a dynamic state of heightened vulnerability to stressors. It is a multidimensional syndrome that places individuals at risk for adverse healt…
View article: A193 COGNITIVE DYSFUNCTION IS PRESENT IN HALF OF STABLE OUTPATIENTS WITH CIRRHOSIS AND IS STRONGLY ASSOCIATED WITH THE POTENTIALLY MODIFICABLE FACTORS, DEPRESSION AND LOW MUSCLE STRENGTH
A193 COGNITIVE DYSFUNCTION IS PRESENT IN HALF OF STABLE OUTPATIENTS WITH CIRRHOSIS AND IS STRONGLY ASSOCIATED WITH THE POTENTIALLY MODIFICABLE FACTORS, DEPRESSION AND LOW MUSCLE STRENGTH Open
BACKGROUND: Impaired cognitive function is a key prognostic factor in patients with cirrhosis. This is often, but not always, attributable to hepatic encephalopathy (HE). The Montreal Cognitive assessment (MOCA) is a sensitive measure of m…
View article: A Scoping Review of Frailty and Acute Care in Middle-Aged and Older Individuals with Recommendations for Future Research
A Scoping Review of Frailty and Acute Care in Middle-Aged and Older Individuals with Recommendations for Future Research Open
There is general agreement that frailty is a state of heightened vulnerability to stressors arising from impairments in multiple systems leading to declines in homeostatic reserve and resiliency, but unresolved issues persist about its det…
View article: A prospective multicenter cohort study of frailty in younger critically ill patients
A prospective multicenter cohort study of frailty in younger critically ill patients Open
Prehospital frailty is common among younger critically ill patients, and in this study it was associated with higher rates of mortality at 1 year and with rehospitalization. Our data suggest that frailty should be considered in younger adu…
View article: Physicians&rsquo; use of computerized clinical decision supports to improve medication management in the elderly &ndash; the Seniors Medication Alert and Review Technology intervention
Physicians’ use of computerized clinical decision supports to improve medication management in the elderly – the Seniors Medication Alert and Review Technology intervention Open
While most SMART alerts validated clinician choices, they were received as valuable reminders for evidence-informed care and education. Data from this study may aid other attempts to implement Beers' Criteria in ambulatory care EMRs.