Daryl Tan
YOU?
Author Swipe
View article: Perspectives on Anti-BCMA Bispecific Antibodies use in Multiple Myeloma–Experience from Asian Countries
Perspectives on Anti-BCMA Bispecific Antibodies use in Multiple Myeloma–Experience from Asian Countries Open
The insights gained will contribute to developing strategic frameworks and consensus guidelines that can effectively guide clinicians in optimizing outcomes for myeloma patients in diverse healthcare settings.
View article: Singapore Myeloma Study Group consensus guidelines for the management of patients with newly diagnosed multiple myeloma
Singapore Myeloma Study Group consensus guidelines for the management of patients with newly diagnosed multiple myeloma Open
Multiple myeloma (MM) is the second most common haematologic malignancy and remains incurable. Significant advances have been made in both supportive care and definitive therapy for MM, leading to marked improvements in survival and qualit…
View article: Weakly Supervised Convolutional Dictionary Learning for Multi-Label Classification
Weakly Supervised Convolutional Dictionary Learning for Multi-Label Classification Open
Convolutional Dictionary Learning (CDL) has emerged as a powerful approach for signal representation by learning translation-invariant features through convolution operations. While existing CDL methods are predominantly designed and used …
View article: Consensus guidelines for the management of treatment-naïve chronic lymphocytic leukaemia in Singapore (2024)
Consensus guidelines for the management of treatment-naïve chronic lymphocytic leukaemia in Singapore (2024) Open
Introduction: Chronic lymphocytic leukaemia (CLL) has a heterogeneous disease course and a variable prevalence across populations. Appropriate management for achieving optimal outcomes requires consideration of multiple factors, including …
View article: Development of a biaxial fibre Bragg grating (FBG) extensometer with axis misalignment error compensation and cloud integration for advanced slope monitoring
Development of a biaxial fibre Bragg grating (FBG) extensometer with axis misalignment error compensation and cloud integration for advanced slope monitoring Open
In the paper, an FBG-based biaxial extensometer is presented to detect ground movement, which is a crucial element in slope monitoring systems. Multiple FBGs were used as displacement sensors to establish sensing nodes at various locations…
View article: A Study on the Spatial Frequency Division Multiplexed of Fiber Bragg Grating-Fabry-Perot Interferometer Sensors with Weak Gratings
A Study on the Spatial Frequency Division Multiplexed of Fiber Bragg Grating-Fabry-Perot Interferometer Sensors with Weak Gratings Open
View article: Evaluating The Performance of Machine Learning Models in Audit Opinion Prediction – A Study in Vietnam
Evaluating The Performance of Machine Learning Models in Audit Opinion Prediction – A Study in Vietnam Open
This study investigates the effectiveness of machine learning models in predicting audit opinions using a dataset from the FiinPro-X platform, comprising 9,783 audited consolidated financial statements from public companies listed on Vietn…
View article: Daratumumab-Based Therapeutic Approaches and Clinical Outcomes in Multiple Myeloma and other Plasma Cell Dyscrasias: Insights from a Nationwide Real-World Chart Review Study
Daratumumab-Based Therapeutic Approaches and Clinical Outcomes in Multiple Myeloma and other Plasma Cell Dyscrasias: Insights from a Nationwide Real-World Chart Review Study Open
Singapore leads Southeast Asia in the routine use of daratumumab for multiple myeloma and other plasma cell dyscrasias. This retrospective review analyzed 112 patients who received daratumumab between 2012 and 2020. Tolerability, and effic…
View article: Consensus recommendations for optimising the diagnosis and treatment of paroxysmal nocturnal haemoglobinuria in Singapore
Consensus recommendations for optimising the diagnosis and treatment of paroxysmal nocturnal haemoglobinuria in Singapore Open
Introduction: Paroxysmal nocturnal haemoglobinuria (PNH) is a rare haematologic disease characterised by intravascular haemolysis, thrombophilia and bone marrow failure. There is a lack of established clinical guidance on the screening, di…
View article: Counterproductive effects of anti-CD38 and checkpoint inhibitor for the treatment of NK/T cell lymphoma
Counterproductive effects of anti-CD38 and checkpoint inhibitor for the treatment of NK/T cell lymphoma Open
Introduction Natural killer/T cell lymphoma (NKTL) is an aggressive malignancy associated with poor prognosis. This is largely due to limited treatment options, especially for relapsed patients. Immunotherapies like immune checkpoint inhib…
View article: AL amyloidosis: Singapore Myeloma Study Group consensus guidelines on diagnosis, treatment and management
AL amyloidosis: Singapore Myeloma Study Group consensus guidelines on diagnosis, treatment and management Open
AL amyloidosis is the most common form of systemic amyloidosis. However, the non-specific nature of presenting symptoms requires the need for a heightened clinical suspicion to detect unexplained manifestations in the appropriate clinical …
View article: Evolving therapeutic landscape of diffuse large B-cell lymphoma: challenges and aspirations
Evolving therapeutic landscape of diffuse large B-cell lymphoma: challenges and aspirations Open
Diffuse large B-cell lymphoma (DLBCL) represents the commonest subtype of non-Hodgkin lymphoma and encompasses a group of diverse disease entities, each harboring unique molecular and clinico-pathological features. The understanding of the…
View article: Supplementary Figure 1 from Janus Kinase 3–Activating Mutations Identified in Natural Killer/T-cell Lymphoma
Supplementary Figure 1 from Janus Kinase 3–Activating Mutations Identified in Natural Killer/T-cell Lymphoma Open
PDF file - 185K, Representative HRM curves of a NKTCL case confirmed as heterozygous JAK3A573V mutation
View article: Supplementary Table 1 from Janus Kinase 3–Activating Mutations Identified in Natural Killer/T-cell Lymphoma
Supplementary Table 1 from Janus Kinase 3–Activating Mutations Identified in Natural Killer/T-cell Lymphoma Open
PDF file - 75K, Sequence analysis summary of tumor and blood samples from four NKTCL cases
View article: Supplementary Table 3 from Janus Kinase 3–Activating Mutations Identified in Natural Killer/T-cell Lymphoma
Supplementary Table 3 from Janus Kinase 3–Activating Mutations Identified in Natural Killer/T-cell Lymphoma Open
PDF file - 83K, JAK1 and JAK3 mutation status in NKTCL cases
View article: Data from Janus Kinase 3–Activating Mutations Identified in Natural Killer/T-cell Lymphoma
Data from Janus Kinase 3–Activating Mutations Identified in Natural Killer/T-cell Lymphoma Open
The molecular pathogenesis of natural killer/T-cell lymphoma (NKTCL) is not well understood. We conducted whole-exome sequencing and identified Janus kinase 3 (JAK3) somatic–activating mutations (A572V and A573V) in 2 of 4 pa…
View article: Supplementary Table 2 from Janus Kinase 3–Activating Mutations Identified in Natural Killer/T-cell Lymphoma
Supplementary Table 2 from Janus Kinase 3–Activating Mutations Identified in Natural Killer/T-cell Lymphoma Open
PDF file - 110K, Non-synonymous somatic mutations identified in the Discovery set of four NKTCL cases
View article: Supplementary Table 3 from Janus Kinase 3–Activating Mutations Identified in Natural Killer/T-cell Lymphoma
Supplementary Table 3 from Janus Kinase 3–Activating Mutations Identified in Natural Killer/T-cell Lymphoma Open
PDF file - 83K, JAK1 and JAK3 mutation status in NKTCL cases
View article: Supplementary Figure 1 from Janus Kinase 3–Activating Mutations Identified in Natural Killer/T-cell Lymphoma
Supplementary Figure 1 from Janus Kinase 3–Activating Mutations Identified in Natural Killer/T-cell Lymphoma Open
PDF file - 185K, Representative HRM curves of a NKTCL case confirmed as heterozygous JAK3A573V mutation
View article: Supplementary Table 4 from Janus Kinase 3–Activating Mutations Identified in Natural Killer/T-cell Lymphoma
Supplementary Table 4 from Janus Kinase 3–Activating Mutations Identified in Natural Killer/T-cell Lymphoma Open
PDF file - 74K, Primer sets used for Sanger sequencing and HRM analysis
View article: Supplementary Table 4 from Janus Kinase 3–Activating Mutations Identified in Natural Killer/T-cell Lymphoma
Supplementary Table 4 from Janus Kinase 3–Activating Mutations Identified in Natural Killer/T-cell Lymphoma Open
PDF file - 74K, Primer sets used for Sanger sequencing and HRM analysis
View article: Supplementary Table 2 from Janus Kinase 3–Activating Mutations Identified in Natural Killer/T-cell Lymphoma
Supplementary Table 2 from Janus Kinase 3–Activating Mutations Identified in Natural Killer/T-cell Lymphoma Open
PDF file - 110K, Non-synonymous somatic mutations identified in the Discovery set of four NKTCL cases
View article: Data from Janus Kinase 3–Activating Mutations Identified in Natural Killer/T-cell Lymphoma
Data from Janus Kinase 3–Activating Mutations Identified in Natural Killer/T-cell Lymphoma Open
The molecular pathogenesis of natural killer/T-cell lymphoma (NKTCL) is not well understood. We conducted whole-exome sequencing and identified Janus kinase 3 (JAK3) somatic–activating mutations (A572V and A573V) in 2 of 4 pa…
View article: Supplementary Table 1 from Janus Kinase 3–Activating Mutations Identified in Natural Killer/T-cell Lymphoma
Supplementary Table 1 from Janus Kinase 3–Activating Mutations Identified in Natural Killer/T-cell Lymphoma Open
PDF file - 75K, Sequence analysis summary of tumor and blood samples from four NKTCL cases
View article: Expert consensus on the management of chronic lymphocytic leukaemia in Asia
Expert consensus on the management of chronic lymphocytic leukaemia in Asia Open
In recent years, considerable progress has been made in the standard treatment for chronic lymphocytic leukaemia (CLL) due to the availability of new potent drugs. However, the majority of data on CLL were derived from Western populations,…
View article: Treatment outcomes of T and natural‐killer/T‐cell lymphoma with ifosfamide, carboplatin and etoposide chemotherapy
Treatment outcomes of T and natural‐killer/T‐cell lymphoma with ifosfamide, carboplatin and etoposide chemotherapy Open
Background Contemporary data of peripheral T‐cell lymphoma (PTCL) and natural‐killer/T‐cell lymphoma (NKTL) patients treated with ifosfamide, carboplatin and etoposide (ICE) are limited. Aims We performed a retrospective analysis to estima…
View article: Counterproductive effects of Daratumumab and checkpoint inhibitor for the treatment of patients with relapsing NK/T lymphoma
Counterproductive effects of Daratumumab and checkpoint inhibitor for the treatment of patients with relapsing NK/T lymphoma Open
Natural killer/T cell lymphoma (NK/T L) is an aggressive malignancy associated with poor prognosis in relapsed patients. Although L-asparaginase based treatments are recommended as first-line treatment in relapsed patients, advances in imm…
View article: Correction to: Whole-genome sequencing identifies responders to Pembrolizumab in relapse/refractory natural-killer/T cell lymphoma
Correction to: Whole-genome sequencing identifies responders to Pembrolizumab in relapse/refractory natural-killer/T cell lymphoma Open
View article: Whole-genome sequencing identifies responders to Pembrolizumab in relapse/refractory natural-killer/T cell lymphoma
Whole-genome sequencing identifies responders to Pembrolizumab in relapse/refractory natural-killer/T cell lymphoma Open
View article: Real world experience of R‐CHOP with or without consolidative radiotherapy vs DA‐EPOCH‐R in the first‐line treatment of primary mediastinal B‐cell lymphoma
Real world experience of R‐CHOP with or without consolidative radiotherapy vs DA‐EPOCH‐R in the first‐line treatment of primary mediastinal B‐cell lymphoma Open
Primary mediastinal large B‐cell lymphoma (PMBCL) is a distinct clinico‐pathological subtype of diffuse large B‐cell lymphoma with unclear prognostic factors and limited clinical data. Optimal treatment and role for radiotherapy is not ful…