Dasheng Lu
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View article: Sex-Specific associations between per- and polyfluoroalkyl substances (PFAS) exposure and spinal posture in Children: The mediating role of bile acid metabolism
Sex-Specific associations between per- and polyfluoroalkyl substances (PFAS) exposure and spinal posture in Children: The mediating role of bile acid metabolism Open
View article: An explainable machine learning model for predicting chronic coronary disease and identifying valuable text features
An explainable machine learning model for predicting chronic coronary disease and identifying valuable text features Open
Background Chronic Coronary Disease (CCD) is a leading global cause of morbidity and mortality. Existing Pre-test Probability (PTP) models mainly rely on in-hospital data and clinician judgment. This study aims to construct machine learnin…
View article: Occurrence, Sources, and Prioritization of Per- and Polyfluoroalkyl Substances (PFASs) in Drinking Water from Yangtze River Delta, China: Focusing on Emerging PFASs
Occurrence, Sources, and Prioritization of Per- and Polyfluoroalkyl Substances (PFASs) in Drinking Water from Yangtze River Delta, China: Focusing on Emerging PFASs Open
As regulations ban legacy PFASs, many emerging PFASs are being developed, leading to their release into the aquatic environment and drinking water. However, research studies on these emerging PFASs in drinking water are limited, and curren…
View article: Assessment of POPs in foods from western China: Machine learning insights into risk and contamination drivers
Assessment of POPs in foods from western China: Machine learning insights into risk and contamination drivers Open
View article: A Systematic Investigation on Contamination of Pesticides and Relevant Metabolites in Pre- and Post-Treatment Drinking Water from the Yangtze River Delta, China
A Systematic Investigation on Contamination of Pesticides and Relevant Metabolites in Pre- and Post-Treatment Drinking Water from the Yangtze River Delta, China Open
This study aimed to investigate the distribution of commonly used pesticides and their metabolites in drinking water before and after treatment at drinking water treatment plants (DWTPs) in the Yangtze River Delta and to assess the health …
View article: Identifying childhood pesticide exposure trajectories and critical window associated with behavioral problems at 10 years of age: Findings from SMBCS
Identifying childhood pesticide exposure trajectories and critical window associated with behavioral problems at 10 years of age: Findings from SMBCS Open
Our study revealed that exposure to pesticides during early childhood (especially before the age of two), rather than other age periods, was linked to hyperactivity/inattention problems in children aged 10 years. We also provided a novel p…
View article: Effect of Temperature, pH, and aw on Cereulide Synthesis and Regulator Genes Transcription with Respect to Bacillus cereus Growth and Cereulide Production
Effect of Temperature, pH, and aw on Cereulide Synthesis and Regulator Genes Transcription with Respect to Bacillus cereus Growth and Cereulide Production Open
Bacillus cereus is a food-borne pathogen that can produce cereulide in the growth period, which causes food poisoning symptoms. Due to its resistance to heat, extreme pH, and proteolytic enzymes, cereulide poses a serious threat to food sa…
View article: Occurrence, Sources and Prioritization of Per-And Polyfluoroalkyl Substances (Pfass) in Drinking Water from Yangtze River Delta, China: Focusing on Emerging Pfass
Occurrence, Sources and Prioritization of Per-And Polyfluoroalkyl Substances (Pfass) in Drinking Water from Yangtze River Delta, China: Focusing on Emerging Pfass Open
View article: Exposure Patterns of Multiple Pesticides and Urinary Alterations of Trimethylamine (TMA) and Trimethylamine N-Oxide (TMAO) among Pregnant Women
Exposure Patterns of Multiple Pesticides and Urinary Alterations of Trimethylamine (TMA) and Trimethylamine N-Oxide (TMAO) among Pregnant Women Open
Environmental exposure to pesticides is widespread and commonly occurs in mixtures, and pregnant women are particularly concerned. Trimethylamine N-oxide (TMAO), a dietary-derived catabolite linked to cardiometabolic disease, may be influe…
View article: Glycine‐β‐muricholic acid antagonizes the intestinal farnesoid X receptor–ceramide axis and ameliorates NASH in mice
Glycine‐β‐muricholic acid antagonizes the intestinal farnesoid X receptor–ceramide axis and ameliorates NASH in mice Open
Nonalcoholic steatohepatitis (NASH) is a rapidly developing pathology around the world, with limited treatment options available. Some farnesoid X receptor (FXR) agonists have been applied in clinical trials for NASH, but side effects such…
View article: Urinary para-nitrophenol levels of pregnant women and cognitive and motor function of their children aged 2 years: Evidence from the SMBCS (China)
Urinary para-nitrophenol levels of pregnant women and cognitive and motor function of their children aged 2 years: Evidence from the SMBCS (China) Open
The mothers from SMBCS may be widely exposed to EP and/or MP, which were associated with the cognitive and motor function of their children aged 2 years in a sex-specific manner. Our results might provide epidemiology evidence on the poten…
View article: Flurochloridone induces responses of free radical reactions and energy metabolism disorders to BRL-3A cell
Flurochloridone induces responses of free radical reactions and energy metabolism disorders to BRL-3A cell Open
View article: The Association between Iodine Intake and Thyroid Cancer/Benign Thyroid Nodules in Shanghai: Two Matched Case-Control Studies
The Association between Iodine Intake and Thyroid Cancer/Benign Thyroid Nodules in Shanghai: Two Matched Case-Control Studies Open
View article: Intestinal farnesoid X receptor signaling controls hepatic fatty acid oxidation
Intestinal farnesoid X receptor signaling controls hepatic fatty acid oxidation Open
View article: Early-life carbamate exposure and intelligence quotient of seven-year-old children
Early-life carbamate exposure and intelligence quotient of seven-year-old children Open
Results of the present study verify that children in an agricultural region of China were widely exposed to carbamate pesticides. Carbamate exposure in utero and at three and seven years may adversely impact children's neurodevelopment.
View article: Comprehensive analysis of transcriptomics and metabolomics to understand triptolide-induced liver injury in mice
Comprehensive analysis of transcriptomics and metabolomics to understand triptolide-induced liver injury in mice Open
View article: Prenatal exposure to mixture of heavy metals, pesticides and phenols and IQ in children at 7 years of age: The SMBCS study
Prenatal exposure to mixture of heavy metals, pesticides and phenols and IQ in children at 7 years of age: The SMBCS study Open
Prenatal exposure to selected chemical mixtures may affect intellectual performance at 7 years of age, particularly in boys. Pb and BPA were suspected as primary chemicals associated with child neurodevelopment.
View article: Intestinal PPARα Protects Against Colon Carcinogenesis via Regulation of Methyltransferases DNMT1 and PRMT6
Intestinal PPARα Protects Against Colon Carcinogenesis via Regulation of Methyltransferases DNMT1 and PRMT6 Open
View article: A systemic workflow for profiling metabolome and lipidome in tissue
A systemic workflow for profiling metabolome and lipidome in tissue Open