Dathan M. Byonanebye
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View article: Health security at genomic artificial intelligence–antimicrobial resistance frontiers in low-income countries
Health security at genomic artificial intelligence–antimicrobial resistance frontiers in low-income countries Open
View article: Distribution and Factors Associated with Neisseria gonorrhoeae Cases in Kampala, Uganda, 2016–2020
Distribution and Factors Associated with Neisseria gonorrhoeae Cases in Kampala, Uganda, 2016–2020 Open
Background: Gonorrhoea is a common sexually transmitted infection with serious health consequences if not well-treated. Resistance to common therapeutic agents and limited diagnostics further heighten its burden on sexual and reproductive …
View article: Application of 7-1-7 framework in prototypical anthrax outbreak: Identifying missed opportunities for early detection in Southwestern Uganda, September 2024
Application of 7-1-7 framework in prototypical anthrax outbreak: Identifying missed opportunities for early detection in Southwestern Uganda, September 2024 Open
Introduction Uganda responded to 37 anthrax outbreaks during 2014–2024. In 2021, the country adopted the 7-1-7 framework, which stipulates detection of outbreaks within seven days, notification completed in one day, and completion of early…
View article: Strengthening Community Antimicrobial Stewardship in Africa: A Systematic Review of the Roles, Challenges, and Opportunities of Community Health and Animal Health Workers
Strengthening Community Antimicrobial Stewardship in Africa: A Systematic Review of the Roles, Challenges, and Opportunities of Community Health and Animal Health Workers Open
Antimicrobial resistance (AMR) remains a critical global health challenge, and is mainly due to inappropriate antimicrobial use in human and animal health sectors. This systematic review examines the roles of Community Animal Health Worker…
View article: Implementation of a cascade training model to enhance emergency care capacity of healthcare workers during the COVID-19 outbreak in Uganda
Implementation of a cascade training model to enhance emergency care capacity of healthcare workers during the COVID-19 outbreak in Uganda Open
There was a general lack of emergency unit protocols and a shortage of fixed staff at the emergency units. The cascade model facilitated the dissemination of emergency care knowledge to seven times more healthcare workers than the trainers…
View article: Prevalence and factors associated with multidrug resistant Escherichia coli carriage on chicken farms in west Nile region in Uganda: A cross-sectional survey
Prevalence and factors associated with multidrug resistant Escherichia coli carriage on chicken farms in west Nile region in Uganda: A cross-sectional survey Open
Infections with multi-drug-resistant (MDR) pathogens in food-animals threaten public health and food security. However, the epidemiology and factors associated with MDR Escherichia coli (MDR E . coli ) on Ugandan farms are not well known. …
View article: Progress on implementing the WHO-GLASS recommendations on priority pathogen-antibiotic sensitivity testing in Africa: A scoping review
Progress on implementing the WHO-GLASS recommendations on priority pathogen-antibiotic sensitivity testing in Africa: A scoping review Open
Introduction The World Health Organization global antimicrobial resistance surveillance system (GLASS) was rolled out in 2015 to guide antimicrobial resistance (AMR) surveillance. However, its implementation in Africa has not been fully ev…
View article: Scaling Up and Enhancing the Functionality of the Electronic Integrated Diseases Surveillance and Response System in Uganda, 2020-2022: Description of the Journey, Challenges, and Lessons Learned
Scaling Up and Enhancing the Functionality of the Electronic Integrated Diseases Surveillance and Response System in Uganda, 2020-2022: Description of the Journey, Challenges, and Lessons Learned Open
In 2017, Uganda implemented an electronic Integrated Disease Surveillance and Response System (eIDSR) to improve data completeness and reporting timelines. However, the eIDSR system had limited functionality and was implemented on a small …
View article: Utility of syndromic surveillance for the surveillance of healthcare-associated infections in resource-limited settings: a narrative review
Utility of syndromic surveillance for the surveillance of healthcare-associated infections in resource-limited settings: a narrative review Open
Globally, Healthcare-associated infections (HCAIs) pose a significant threat to patient safety and healthcare systems. In low- and middle-income countries (LMICs), the lack of adequate resources to manage HCAIs, as well as the weak healthc…
View article: COVID-19 self-medication practices among slum dwellers in Jinja City, Uganda
COVID-19 self-medication practices among slum dwellers in Jinja City, Uganda Open
Introduction: Self-medication is one of the elements of self-care, which the World Health Organization (WHO) defines as the selection and use of medicines to treat self-identified symptoms or ailments without consulting a physician. Self-m…
View article: Prevalence and factors associated with self-medication for COVID-19 among slum dwellers in Jinja City, Uganda, in 2021
Prevalence and factors associated with self-medication for COVID-19 among slum dwellers in Jinja City, Uganda, in 2021 Open
Introduction: Self-medication is a serious public health concern globally and is more prevalent in underserved populations, especially in resource limited settings. The lack of effective treatment for COVID-19 and poor access to healthcare…
View article: Progress of Implementation of World Health Organization Global Antimicrobial Resistance Surveillance System Recommendations on Priority Pathogen-Antibiotic Sensitivity Testing in Africa: Protocol for a Scoping Review
Progress of Implementation of World Health Organization Global Antimicrobial Resistance Surveillance System Recommendations on Priority Pathogen-Antibiotic Sensitivity Testing in Africa: Protocol for a Scoping Review Open
Background Antimicrobial resistance (AMR) is a major global public health concern, particularly in low- and middle-income countries where resources and infrastructure for an adequate response are limited. The World Health Organization (WHO…
View article: Combating Antimicrobial Resistance Through a Data-Driven Approach to Optimize Antibiotic Use and Improve Patient Outcomes: Protocol for a Mixed Methods Study
Combating Antimicrobial Resistance Through a Data-Driven Approach to Optimize Antibiotic Use and Improve Patient Outcomes: Protocol for a Mixed Methods Study Open
Background It is projected that drug-resistant infections will lead to 10 million deaths annually by 2050 if left unabated. Despite this threat, surveillance data from resource-limited settings are scarce and often lack antimicrobial resis…
View article: Enhancing functionality and scaling up of the electronic Integrated Diseases Surveillance and Response system in Uganda, 2020-2023: Description of the journey, challenges, and lessons learned (Preprint)
Enhancing functionality and scaling up of the electronic Integrated Diseases Surveillance and Response system in Uganda, 2020-2023: Description of the journey, challenges, and lessons learned (Preprint) Open
BACKGROUND In 2017, Uganda implemented an electronic Integrated Disease Surveillance and Response System (eIDSR) to improve data completeness and reporting timelines. However, the eIDSR system had limited functionality and was implemented…
View article: Associations between change in BMI and the risk of hypertension and dyslipidaemia in people receiving integrase strand-transfer inhibitors, tenofovir alafenamide, or both compared with other contemporary antiretroviral regimens: a multicentre, prospective observational study from the RESPOND consortium cohorts
Associations between change in BMI and the risk of hypertension and dyslipidaemia in people receiving integrase strand-transfer inhibitors, tenofovir alafenamide, or both compared with other contemporary antiretroviral regimens: a multicentre, prospective observational study from the RESPOND consortium cohorts Open
View article: Combating Antimicrobial Resistance Through a Data-Driven Approach to Optimize Antibiotic Use and Improve Patient Outcomes: Protocol for a Mixed Methods Study (Preprint)
Combating Antimicrobial Resistance Through a Data-Driven Approach to Optimize Antibiotic Use and Improve Patient Outcomes: Protocol for a Mixed Methods Study (Preprint) Open
BACKGROUND It is projected that drug-resistant infections will lead to 10 million deaths annually by 2050 if left unabated. Despite this threat, surveillance data from resource-limited settings are scarce and often lack antimicrobial resi…
View article: Progress of Implementation of World Health Organization Global Antimicrobial Resistance Surveillance System Recommendations on Priority Pathogen-Antibiotic Sensitivity Testing in Africa: Protocol for a Scoping Review (Preprint)
Progress of Implementation of World Health Organization Global Antimicrobial Resistance Surveillance System Recommendations on Priority Pathogen-Antibiotic Sensitivity Testing in Africa: Protocol for a Scoping Review (Preprint) Open
BACKGROUND Antimicrobial resistance (AMR) is a major global public health concern, particularly in low- and middle-income countries where resources and infrastructure for an adequate response are limited. The World Health Organization (WH…
View article: Prevalence and Factors Associated with Multidrug Resistant E. coli Carriage on Chicken Farms in West Nile Region in Uganda: A Cross-Sectional Survey
Prevalence and Factors Associated with Multidrug Resistant E. coli Carriage on Chicken Farms in West Nile Region in Uganda: A Cross-Sectional Survey Open
Infections with multi-drug-resistant (MDR) pathogens in food-animals threaten public health and food security. However, the epidemiology and factors associated with MDR Escherichia coli on Ugandan farms are not well known. This study inves…
View article: Prevalence and predictors of self-medication for COVID-19 among slum dwellers in Jinja City, Uganda
Prevalence and predictors of self-medication for COVID-19 among slum dwellers in Jinja City, Uganda Open
Introduction Self-medication is a serious public health concern globally and is more prevalent in underserved populations, especially in resource limited settings. The lack of effective treatment for COVID-19 and poor access to healthcare …
View article: Prevalence and incidence of hypertension in a heavily treatment-experienced cohort of people living with HIV in Uganda
Prevalence and incidence of hypertension in a heavily treatment-experienced cohort of people living with HIV in Uganda Open
Introduction The effect of long-term exposure to antiretroviral therapy (ART) on hypertension in sub-Saharan Africa remains unclear. We aimed to determine the prevalence and incidence of hypertension in people living with HIV (PLWH) with m…
View article: Incidence of hypertension in people with HIV who are treated with integrase inhibitors versus other antiretroviral regimens in the RESPOND cohort consortium
Incidence of hypertension in people with HIV who are treated with integrase inhibitors versus other antiretroviral regimens in the RESPOND cohort consortium Open
Objective To compare the incidence of hypertension in people living with HIV receiving integrase strand transfer inhibitor (INSTI)‐based antiretroviral therapy (ART) versus non‐nucleoside reverse transcriptase inhibitors (NNRTIs) or booste…
View article: Occupational Injuries and use of Personal Protective Equipment among Casual Municipal Solid Waste Workers in the Informal Sector in Kampala: A Cross-Sectional Study.
Occupational Injuries and use of Personal Protective Equipment among Casual Municipal Solid Waste Workers in the Informal Sector in Kampala: A Cross-Sectional Study. Open
Introduction: The risk of occupational injuries in municipal solid waste workers in most low- and middle-income countries is increasing. This study sought to determine the use of PPE and its association with injuries among casual waste wor…
View article: Impact of a mobile phone-based interactive voice response software on tuberculosis treatment outcomes in Uganda (CFL-TB): a protocol for a randomized controlled trial
Impact of a mobile phone-based interactive voice response software on tuberculosis treatment outcomes in Uganda (CFL-TB): a protocol for a randomized controlled trial Open
View article: Factors that Influence Satisfaction of People Living with HIV(PLHIV) with Differentiated ART Delivery Models in East Central Uganda: A Cross-Sectional Study
Factors that Influence Satisfaction of People Living with HIV(PLHIV) with Differentiated ART Delivery Models in East Central Uganda: A Cross-Sectional Study Open
Background The World Health Organization and Uganda Ministry of Health recommend differentiated service delivery models (DSDM) as patient-focussed approaches for delivering antiretroviral therapy for people living with HIV/AIDS (PLHIV) who…
View article: An Interactive Voice Response Software to Improve the Quality of Life of People Living With HIV in Uganda: Randomized Controlled Trial
An Interactive Voice Response Software to Improve the Quality of Life of People Living With HIV in Uganda: Randomized Controlled Trial Open
Background Following the successful scale-up of antiretroviral therapy (ART), the focus is now on ensuring good quality of life (QoL) and sustained viral suppression in people living with HIV. The access to mobile technology in the most bu…
View article: An Interactive Voice Response Software to Improve the Quality of Life of People Living With HIV in Uganda: Randomized Controlled Trial (Preprint)
An Interactive Voice Response Software to Improve the Quality of Life of People Living With HIV in Uganda: Randomized Controlled Trial (Preprint) Open
BACKGROUND Following the successful scale-up of antiretroviral therapy (ART), the focus is now on ensuring good quality of life (QoL) and sustained viral suppression in people living with HIV. The access to mobile technology in the most b…
View article: Absolute eosinophil count correlates with temperature and CD4 count independently of HIV infection among tuberculosis patients
Absolute eosinophil count correlates with temperature and CD4 count independently of HIV infection among tuberculosis patients Open
Objective To determine clinical correlates of the peripheral absolute eosinophil count (AEC) among bacteriologically confirmed TB patients in Uganda. Materials and Methods We evaluated data of bacteriologically confirmed adult TB patients …
View article: High viral suppression and low attrition in healthy HIV-infected patients initiated on ART with CD4 above 500 cells/μL in a program setting in Uganda
High viral suppression and low attrition in healthy HIV-infected patients initiated on ART with CD4 above 500 cells/μL in a program setting in Uganda Open
Background: The World Health Organization recommends antiretroviral therapy (ART) for all HIV-infected patients at all CD4 counts. However, there are concerns that asymptomatic patients may have poorer viral suppression and high attrition.…
View article: Correlates of uptake of optimal doses of sulfadoxine-pyrimethamine for prevention of malaria during pregnancy in East-Central Uganda
Correlates of uptake of optimal doses of sulfadoxine-pyrimethamine for prevention of malaria during pregnancy in East-Central Uganda Open
View article: Hypertension control in integrated HIV and chronic disease clinics in Uganda in the SEARCH study
Hypertension control in integrated HIV and chronic disease clinics in Uganda in the SEARCH study Open