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View article: Reported Incidence of Infections Caused by Pathogens Transmitted Commonly Through Food: Impact of Increased Use of Culture-Independent Diagnostic Tests — Foodborne Diseases Active Surveillance Network, 1996–2023
Reported Incidence of Infections Caused by Pathogens Transmitted Commonly Through Food: Impact of Increased Use of Culture-Independent Diagnostic Tests — Foodborne Diseases Active Surveillance Network, 1996–2023 Open
Reducing foodborne disease incidence is a public health priority. This report summarizes preliminary 2023 Foodborne Diseases Active Surveillance Network (FoodNet) data and highlights efforts to increase the representativeness of FoodNet. D…
View article: Antimicrobial Synergy between Aminoglycosides and Licorice Extract in Listeria monocytogenes
Antimicrobial Synergy between Aminoglycosides and Licorice Extract in Listeria monocytogenes Open
Listeria monocytogenes is a foodborne pathogen that can develop serious invasive infections. Among foodborne pathogens, L. monocytogenes exhibits the highest case fatality despite antibiotic treatment, suggesting the current therapy should…
View article: Transmission of Multidrug-Resistant Salmonella enterica Subspecies enterica 4,[5],12:i:- Sequence Type 34 between Europe and the United States
Transmission of Multidrug-Resistant Salmonella enterica Subspecies enterica 4,[5],12:i:- Sequence Type 34 between Europe and the United States Open
Multidrug-resistant Salmonella enterica subspecies enterica 4,[5],12:i:- sequence type 34 represents a worldwide public health risk. To determine its origin in the United States, we reconstructed a time-scaled phylogeny with a discrete tra…
View article: Emergence of a Novel Salmonella enterica Serotype Reading Clonal Group Is Linked to Its Expansion in Commercial Turkey Production, Resulting in Unanticipated Human Illness in North America
Emergence of a Novel Salmonella enterica Serotype Reading Clonal Group Is Linked to Its Expansion in Commercial Turkey Production, Resulting in Unanticipated Human Illness in North America Open
Increasingly, outbreak investigations involving foodborne pathogens are difficult due to the interconnectedness of food animal production and distribution, and homogeneous nature of industry integration, necessitating high-resolution genom…
View article: Prospective<i>Salmonella</i>Enteritidis surveillance and outbreak detection using whole genome sequencing, Minnesota 2015–2017
Prospective<i>Salmonella</i>Enteritidis surveillance and outbreak detection using whole genome sequencing, Minnesota 2015–2017 Open
Clusters of Salmonella Enteritidis cases were identified by the Minnesota Department of Health using both pulsed-field gel electrophoresis (PFGE) and whole genome sequencing (WGS) single nucleotide polymorphism analysis from 1 January 2015…
View article: Emergence of a novel<i>Salmonella enterica</i>serotype Reading clone is linked to its expansion in commercial turkey production, resulting in unanticipated human illness in North America
Emergence of a novel<i>Salmonella enterica</i>serotype Reading clone is linked to its expansion in commercial turkey production, resulting in unanticipated human illness in North America Open
Concurrent separate human outbreaks of Salmonella enterica serotype Reading occurred in 2017-2019 in the United States and Canada, which were both linked to the consumption of raw turkey products. In this study, a comprehensive genomic inv…
View article: Conservation and global distribution of non-canonical antigens in Enterotoxigenic Escherichia coli
Conservation and global distribution of non-canonical antigens in Enterotoxigenic Escherichia coli Open
EtpA and EatA are well-conserved molecules in the ETEC pathovar, suggesting that they serve important roles in virulence and that they could be exploited for rational vaccine design.
View article: A66 Tracing the evolutionary history of an emerging Salmonella 4,[5],12:i:- clone in the United States
A66 Tracing the evolutionary history of an emerging Salmonella 4,[5],12:i:- clone in the United States Open
Salmonellosis is one of the leading causes of foodborne disease worldwide, with an estimated one million cases a year in the United States. Salmonella 4,[5],12: i:-, a monophasic variant of Salmonella typhimurium, is an emerging serovar th…
View article: Influenza Antiviral Prescribing Practices and the Influence of Rapid Testing Among Primary Care Providers in the US, 2009–2016
Influenza Antiviral Prescribing Practices and the Influence of Rapid Testing Among Primary Care Providers in the US, 2009–2016 Open
Background Early influenza antiviral treatment within 2 days of illness onset can reduce illness severity and duration. Reliance on low sensitivity rapid influenza diagnostic tests (RIDTs) to guide antiviral prescribing has been reported. …
View article: Circulation of Plasmids Harboring Resistance Genes to Quinolones and/or Extended-Spectrum Cephalosporins in Multiple <i>Salmonella enterica</i> Serotypes from Swine in the United States
Circulation of Plasmids Harboring Resistance Genes to Quinolones and/or Extended-Spectrum Cephalosporins in Multiple <i>Salmonella enterica</i> Serotypes from Swine in the United States Open
Nontyphoidal Salmonella enterica (NTS) poses a major public health risk worldwide that is amplified by the existence of antimicrobial-resistant strains, especially those resistant to quinolones and extended-spectrum cephalosporins (ESC). L…
View article: Zoonotic Source Attribution of<i>Salmonella enterica</i>Serotype Typhimurium Using Genomic Surveillance Data, United States
Zoonotic Source Attribution of<i>Salmonella enterica</i>Serotype Typhimurium Using Genomic Surveillance Data, United States Open
Increasingly, routine surveillance and monitoring of foodborne pathogens using whole-genome sequencing is creating opportunities to study foodborne illness epidemiology beyond routine outbreak investigations and case-control studies. Using…
View article: Burdens of Invasive Methicillin-Susceptible and Methicillin-Resistant <i>Staphylococcus aureus</i> Disease, Minnesota, USA
Burdens of Invasive Methicillin-Susceptible and Methicillin-Resistant <i>Staphylococcus aureus</i> Disease, Minnesota, USA Open
During August 1, 2014-July 31, 2015, in 2 counties in Minnesota, USA, incidence of invasive methicillin-susceptible Staphylococcus aureus (MSSA) (27.1 cases/100,000 persons) was twice that of invasive methicillin-resistant S. aureus (13.1 …
View article: 473. Molecular Typing of <i>Clostridium difficile</i>: Concordance Between PCR-Ribotyping and Multilocus Sequence Typing (MLST)
473. Molecular Typing of <i>Clostridium difficile</i>: Concordance Between PCR-Ribotyping and Multilocus Sequence Typing (MLST) Open
BACKGROUND: Clostridium difficile infection (CDI) incidence has increased dramatically in the past decade, making CDI one of the most common causes of infectious diarrhea and an urgent public health threat. Understanding the biological fea…
View article: Draft Genome Sequences for a Diverse Set of Seven <i>Haemophilus</i> and <i>Aggregatibacter</i> Species
Draft Genome Sequences for a Diverse Set of Seven <i>Haemophilus</i> and <i>Aggregatibacter</i> Species Open
Haemophilus is a complex genus that includes commensal and pathogenic species that pose a public health threat to humans. While the pathogenic species have been studied extensively, many commensals have limited genomic information availabl…
View article: Draft Genome Sequences for a Diverse Set of Isolates from 10 Neisseria Species
Draft Genome Sequences for a Diverse Set of Isolates from 10 Neisseria Species Open
Neisseria is a diverse genus that includes commensal and pathogenic species that pose a public health threat. While the pathogenic species have been studied extensively, many of the commensals have limited genomic information available. He…
View article: Additional file 5: of BMScan: using whole genome similarity to rapidly and accurately identify bacterial meningitis causing species
Additional file 5: of BMScan: using whole genome similarity to rapidly and accurately identify bacterial meningitis causing species Open
BioProject and PubMLST Ids for genome assemblies used in reference collection. (XLSX 17 kb)
View article: Additional file 4: of BMScan: using whole genome similarity to rapidly and accurately identify bacterial meningitis causing species
Additional file 4: of BMScan: using whole genome similarity to rapidly and accurately identify bacterial meningitis causing species Open
Results of validation test. (CSV 2265 kb)
View article: Additional file 2: of BMScan: using whole genome similarity to rapidly and accurately identify bacterial meningitis causing species
Additional file 2: of BMScan: using whole genome similarity to rapidly and accurately identify bacterial meningitis causing species Open
Reference collection excel file with meta-data. (XLSX 41 kb)
View article: Salmonella enterica Serotype 4,[5],12:i:- in Swine in the United States Midwest: An Emerging Multidrug-Resistant Clade
Salmonella enterica Serotype 4,[5],12:i:- in Swine in the United States Midwest: An Emerging Multidrug-Resistant Clade Open
Salmonella 4,[5],12:i:- currently circulating in swine in the US Midwest are likely to be part of an emerging multidrug-resistant clade first reported in Europe, and can carry plasmid-mediated resistance genes that may be transmitted horiz…
View article: ICD-9 code reporting among patients from the Minnesota SARI surveillance program
ICD-9 code reporting among patients from the Minnesota SARI surveillance program Open
IntroductionThe ICD-9 codes for acute respiratory illness (ARI) andpneumonia/influenza (P&I) are commonly used in ARI surveillance;however, few studies evaluate the accuracy of these codes or theimportance of ICD-9 position. We reviewed IC…
View article: Comparison of Whole-Genome Sequencing Methods for Analysis of Three Methicillin-Resistant Staphylococcus aureus Outbreaks
Comparison of Whole-Genome Sequencing Methods for Analysis of Three Methicillin-Resistant Staphylococcus aureus Outbreaks Open
Whole-genome sequencing (WGS) can provide excellent resolution in global and local epidemiological investigations of Staphylococcus aureus outbreaks. A variety of sequencing approaches and analytical tools have been used; it is not clear w…
View article: Community Laboratory Testing for Cryptosporidium: Multicenter Study Retesting Public Health Surveillance Stool Samples Positive for Cryptosporidium by Rapid Cartridge Assay with Direct Fluorescent Antibody Testing
Community Laboratory Testing for Cryptosporidium: Multicenter Study Retesting Public Health Surveillance Stool Samples Positive for Cryptosporidium by Rapid Cartridge Assay with Direct Fluorescent Antibody Testing Open
Cryptosporidium is a common cause of sporadic diarrheal disease and outbreaks in the United States. Increasingly, immunochromatography-based rapid cartridge assays (RCAs) are providing community laboratories with a quick cryptosporidiosis …
View article: Comparison of Respiratory Pathogen Detections from Routine Hospital Testing and Expanded Systematic Testing from the Minnesota Severe Acute Respiratory Illness Surveillance Program, 2015–2016
Comparison of Respiratory Pathogen Detections from Routine Hospital Testing and Expanded Systematic Testing from the Minnesota Severe Acute Respiratory Illness Surveillance Program, 2015–2016 Open
Background Hospital testing for respiratory pathogens is nonsystematic, leading to potential missed detection of clinically relevant pathogens. The Minnesota Severe Acute Respiratory Illness (SARI) surveillance program monitors hospitaliza…
View article: Vaccine effectiveness against influenza-associated hospitalization among children aged &lt; 13 years using a hospital-based surveillance system in Minnesota, 2013 – 2016
Vaccine effectiveness against influenza-associated hospitalization among children aged < 13 years using a hospital-based surveillance system in Minnesota, 2013 – 2016 Open
Background Due to marked variability in circulating influenza viruses each year, annual evaluation of the vaccine’s effectiveness against severe outcomes is essential. We used the Minnesota Department of Health’s (MDH) Severe Acute Respira…
View article: Viral and Bacterial Co-Detections in Influenza-Positive Patients Hospitalized With Severe Acute Respiratory Illness—Minnesota, 2013–2015
Viral and Bacterial Co-Detections in Influenza-Positive Patients Hospitalized With Severe Acute Respiratory Illness—Minnesota, 2013–2015 Open
Background.Sensitive molecular and multi-pathogen testing has resulted in increased detection of respiratory pathogens, including co-detection of multiple pathogens.The impact of co-detections on patients hospitalized with influenza is unc…
View article: Clonal Dissemination of Enterobacter cloacae Harboring <i>bla</i> <sub>KPC-3</sub> in the Upper Midwestern United States
Clonal Dissemination of Enterobacter cloacae Harboring <i>bla</i> <sub>KPC-3</sub> in the Upper Midwestern United States Open
Carbapenemase-producing, carbapenem-resistant Enterobacteriaceae , or CP-CRE, are an emerging threat to human and animal health, because they are resistant to many of the last-line antimicrobials available for disease treatment. Carbapenem…
View article: Effect of Culture-Independent Diagnostic Tests on Future Emerging Infections Program Surveillance
Effect of Culture-Independent Diagnostic Tests on Future Emerging Infections Program Surveillance Open
The Centers for Disease Control and Prevention Emerging Infections Program (EIP) network conducts population-based surveillance for pathogens of public health importance. Central to obtaining estimates of disease burden and tracking microb…