David Schoenfeld
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View article: 376 Predicting Emergency Department Arrivals by Ambulance Versus Walk-In for Patients After Sexual Assault, 2022-2024
376 Predicting Emergency Department Arrivals by Ambulance Versus Walk-In for Patients After Sexual Assault, 2022-2024 Open
View article: The missing self in time: Duration reproductions diverge when using the “self” as a reference point
The missing self in time: Duration reproductions diverge when using the “self” as a reference point Open
View article: Akt Activation With <scp>IPL344</scp> Treatment for Amyotrophic Lateral Sclerosis: First in Human, Open‐Label Study
Akt Activation With <span>IPL344</span> Treatment for Amyotrophic Lateral Sclerosis: First in Human, Open‐Label Study Open
Introduction/Aims Akt intracellular signal transduction pathway dysfunction has been reported in people with amyotrophic lateral sclerosis (ALS) providing a novel target for intervention in this devastating progressive disease. This first‐…
View article: Community Health Worker Support and Clinician Education for Tobacco Cessation in Adults with Serious Mental Illness: A Pragmatic, Cluster-Randomized Clinical Trial
Community Health Worker Support and Clinician Education for Tobacco Cessation in Adults with Serious Mental Illness: A Pragmatic, Cluster-Randomized Clinical Trial Open
View article: P.026 Success with incrementally faster times to endovascular therapy (SWIFT-EVT): a systematic review and meta-analysis
P.026 Success with incrementally faster times to endovascular therapy (SWIFT-EVT): a systematic review and meta-analysis Open
Background: Previous research demonstrates that for acute ischemic stroke (AIS) cases, rapid endovascular therapy (EVT) performance improves outcomes. This study provides updated metrics summarizing estimates for modified Rankin Scale (mRS…
View article: Contents
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View article: Supplementary Methods, Table 1, Figures 1-6 from Expression of the p53 Target CDIP Correlates with Sensitivity to TNFα-Induced Apoptosis in Cancer Cells
Supplementary Methods, Table 1, Figures 1-6 from Expression of the p53 Target CDIP Correlates with Sensitivity to TNFα-Induced Apoptosis in Cancer Cells Open
PDF file - 1.6MB, Table 1. Primers used for real-time PCR analysis of NF-kB target gene expression. Fig. S1. Recombinant human TNF�� rescues CDIP apoptosis in TNF�� knockdown cells. Fig. S2. TNF�� signaling was assessed in U2OS-CDIP cells …
View article: Supplementary Methods, Table 1, Figures 1-6 from Expression of the p53 Target CDIP Correlates with Sensitivity to TNFα-Induced Apoptosis in Cancer Cells
Supplementary Methods, Table 1, Figures 1-6 from Expression of the p53 Target CDIP Correlates with Sensitivity to TNFα-Induced Apoptosis in Cancer Cells Open
PDF file - 1.6MB, Table 1. Primers used for real-time PCR analysis of NF-kB target gene expression. Fig. S1. Recombinant human TNF�� rescues CDIP apoptosis in TNF�� knockdown cells. Fig. S2. TNF�� signaling was assessed in U2OS-CDIP cells …
View article: Randomized, double-blinded, placebo-controlled trial of allogeneic cord blood T-regulatory cells for treatment of COVID-19 ARDS
Randomized, double-blinded, placebo-controlled trial of allogeneic cord blood T-regulatory cells for treatment of COVID-19 ARDS Open
View article: A randomized controlled trial of resistance and endurance exercise in amyotrophic lateral sclerosis
A randomized controlled trial of resistance and endurance exercise in amyotrophic lateral sclerosis Open
Objective: Evaluate the safety and tolerability of resistance and endurance exercise in ALS participants as measured by their ability to complete this six-month study. Methods: Participants were randomized to Resistance, Endu…
View article: RF06 | PSAT171 Impact of GH Administration on Skeletal Endpoints in Adults with Overweight/Obesity
RF06 | PSAT171 Impact of GH Administration on Skeletal Endpoints in Adults with Overweight/Obesity Open
Background Obesity is associated with relative growth hormone (GH) deficiency and increased fracture risk. We hypothesized that GH administration would improve bone endpoints in individuals with overweight/obesity. Methods 77 adults ages 1…
View article: Computer clinical decision support that automates personalized clinical care: a challenging but needed healthcare delivery strategy
Computer clinical decision support that automates personalized clinical care: a challenging but needed healthcare delivery strategy Open
How to deliver best care in various clinical settings remains a vexing problem. All pertinent healthcare-related questions have not, cannot, and will not be addressable with costly time- and resource-consuming controlled clinical trials. A…
View article: The Use of IV Vasoactive Intestinal Peptide (Aviptadil) in Patients With Critical COVID-19 Respiratory Failure: Results of a 60-Day Randomized Controlled Trial*
The Use of IV Vasoactive Intestinal Peptide (Aviptadil) in Patients With Critical COVID-19 Respiratory Failure: Results of a 60-Day Randomized Controlled Trial* Open
OBJECTIVES: Respiratory failure is a lethal complication of COVID-19 that has remained resistant to drug therapy. Vasoactive intestinal peptide (VIP) is shown in nonclinical studies to upregulate surfactant production, inhibit cytokine syn…
View article: Multiple BCG vaccinations for the prevention of COVID-19 and other infectious diseases in type 1 diabetes
Multiple BCG vaccinations for the prevention of COVID-19 and other infectious diseases in type 1 diabetes Open
There is a need for safe and effective platform vaccines to protect against coronavirus disease 2019 (COVID-19) and other infectious diseases. In this randomized, double-blinded, placebo-controlled phase 2/3 trial, we evaluate the safety a…
View article: Triple Threat: A Case of Erysipelothrix rhusiopathiae Septicemia Complicated by Multi-Valvular Endocarditis, Spinal Osteomyelitis, and Septic Embolic Stroke
Triple Threat: A Case of Erysipelothrix rhusiopathiae Septicemia Complicated by Multi-Valvular Endocarditis, Spinal Osteomyelitis, and Septic Embolic Stroke Open
Erysipelothrix rhusiopathiae is a Gram-positive rod associated with zoonotic infections, most commonly the soft tissues. It can be present in several ways, though most commonly as erysipeloid. Rarely, it may manifest systemically wi…
View article: Randomised, pragmatic, waitlist controlled trial of cannabis added to prescription opioid support on opioid dose reduction and pain in adults with chronic non-cancer pain: study protocol
Randomised, pragmatic, waitlist controlled trial of cannabis added to prescription opioid support on opioid dose reduction and pain in adults with chronic non-cancer pain: study protocol Open
Introduction Chronic, non-cancer pain impacts approximately 50 million adults in the USA (20%), approximately 25% of whom receive chronic prescription opioids for pain despite limited empirical efficacy data and strong dose-related risk fo…
View article: Impact of GH administration on skeletal endpoints in adults with overweight/obesity
Impact of GH administration on skeletal endpoints in adults with overweight/obesity Open
Objective Overweight/obesity is associated with relative growth hormone (GH) deficiency and increased fracture risk. We hypothesized that GH administration would improve bone endpoints in individuals with overweight/obesity. Design An 18-m…
View article: Effect of Medical Marijuana Card Ownership on Pain, Insomnia, and Affective Disorder Symptoms in Adults
Effect of Medical Marijuana Card Ownership on Pain, Insomnia, and Affective Disorder Symptoms in Adults Open
ClinicalTrials.gov Identifier: NCT03224468.
View article: Severe cerebral edema in substance-related cardiac arrest patients
Severe cerebral edema in substance-related cardiac arrest patients Open
View article: Provider Education with or Without Community Health Worker Support for Tobacco Cessation in Adults with Serious Mental Illness: A Cluster Randomized Clinical Trial
Provider Education with or Without Community Health Worker Support for Tobacco Cessation in Adults with Serious Mental Illness: A Cluster Randomized Clinical Trial Open
View article: Bacillus Cereus bacteremia complicated by brain abscess in a severely immunocompromised patient: Addressing importance of early recognition and challenges in diagnosis
Bacillus Cereus bacteremia complicated by brain abscess in a severely immunocompromised patient: Addressing importance of early recognition and challenges in diagnosis Open
Bacillus cereus (B. cereus) is a known cause of a food poisoning in the general population. However, it can cause life-threatening sepsis and shock in severely immunocompromised patients with hematologic malignancies, which f…
View article: Sequential Therapy With Recombinant Human IGF-1 Followed by Risedronate Increases Spine Bone Mineral Density in Women With Anorexia Nervosa: A Randomized, Placebo-Controlled Trial
Sequential Therapy With Recombinant Human IGF-1 Followed by Risedronate Increases Spine Bone Mineral Density in Women With Anorexia Nervosa: A Randomized, Placebo-Controlled Trial Open
Anorexia nervosa is complicated by low bone mineral density (BMD) and increased fracture risk associated with low bone formation and high bone resorption. The lumbar spine is most severely affected. Low bone formation is associated with re…
View article: Author response for "Sequential therapy with recombinant human IGF ‐1 followed by risedronate increases spine bone mineral density in women with anorexia nervosa: A randomized, placebo‐controlled trial"
Author response for "Sequential therapy with recombinant human IGF ‐1 followed by risedronate increases spine bone mineral density in women with anorexia nervosa: A randomized, placebo‐controlled trial" Open
View article: Author response for "Sequential therapy with recombinant human IGF ‐1 followed by risedronate increases spine bone mineral density in women with anorexia nervosa: A randomized, placebo‐controlled trial"
Author response for "Sequential therapy with recombinant human IGF ‐1 followed by risedronate increases spine bone mineral density in women with anorexia nervosa: A randomized, placebo‐controlled trial" Open
View article: Author response for "Sequential therapy with recombinant human IGF ‐1 followed by risedronate increases spine bone mineral density in women with anorexia nervosa: A randomized, placebo‐controlled trial"
Author response for "Sequential therapy with recombinant human IGF ‐1 followed by risedronate increases spine bone mineral density in women with anorexia nervosa: A randomized, placebo‐controlled trial" Open
View article: Sequential Therapy With Recombinant Human IGF-1 Followed by Risedronate Increases Spine Bone Mineral Density in Women With Anorexia Nervosa
Sequential Therapy With Recombinant Human IGF-1 Followed by Risedronate Increases Spine Bone Mineral Density in Women With Anorexia Nervosa Open
Anorexia nervosa is complicated by low bone mineral density (BMD) and increased fracture risk associated with low bone formation and high bone resorption. The spine, particularly its trabecular component as measured by lateral spine dual-e…
View article: Predictors and moderators of symptom change during cognitive-behavioral therapy or supportive psychotherapy for body dysmorphic disorder
Predictors and moderators of symptom change during cognitive-behavioral therapy or supportive psychotherapy for body dysmorphic disorder Open
View article: Effect of Transdermal Estradiol and Insulin-like Growth Factor-1 on Bone Endpoints of Young Women With Anorexia Nervosa
Effect of Transdermal Estradiol and Insulin-like Growth Factor-1 on Bone Endpoints of Young Women With Anorexia Nervosa Open
Context Anorexia nervosa (AN) is prevalent in adolescent girls and is associated with bone impairment driven by hormonal alterations in nutritional deficiency. Objective To assess the impact of estrogen replacement with and without recombi…
View article: Safety Assessment of a Noninvasive Respiratory Protocol for Adults With COVID‐19
Safety Assessment of a Noninvasive Respiratory Protocol for Adults With COVID‐19 Open
As evidence emerged supporting noninvasive strategies for coronavirus disease 2019 (COVID‐19)–related respiratory distress, we implemented a noninvasive COVID‐19 respiratory protocol (NCRP) that encouraged high‐flow nasal cannula (HFNC) an…
View article: Enabling a learning healthcare system with automated computer protocols that produce replicable and personalized clinician actions
Enabling a learning healthcare system with automated computer protocols that produce replicable and personalized clinician actions Open
Clinical decision-making is based on knowledge, expertise, and authority, with clinicians approving almost every intervention—the starting point for delivery of “All the right care, but only the right care,” an unachieved healthcare qualit…