David Abernethy
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View article: Joint associations of physical activity and body mass index on the prevalence of hypertension among a nationally representative sample of 1.9 million U.S. adults: A cross-sectional study
Joint associations of physical activity and body mass index on the prevalence of hypertension among a nationally representative sample of 1.9 million U.S. adults: A cross-sectional study Open
A high body mass and low levels of PA were associated with a substantially increased prevalence of hypertension. Being highly active was associated with minor differences in the prevalence of hypertension for individuals who were living wi…
View article: Temporal trends in aerobic physical activity guideline adherence among nationally representative samples of U.S adults between 2011 and 2019: Cross-sectional findings from a sample of over 2 million adults
Temporal trends in aerobic physical activity guideline adherence among nationally representative samples of U.S adults between 2011 and 2019: Cross-sectional findings from a sample of over 2 million adults Open
Background Physical inactivity is a significant public health concern associated with numerous adverse health outcomes and substantial economic costs. This study describes the prevalence, trends and correlates for adherence to moderate to …
View article: Joint Effects of Physical Activity and Body Mass Index on Prevalent Diabetes in a Nationally Representative Sample of 1.9 Million US Adults
Joint Effects of Physical Activity and Body Mass Index on Prevalent Diabetes in a Nationally Representative Sample of 1.9 Million US Adults Open
Aim: To investigate the joint effects of physical activity (PA) and body mass index (BMI) on prevalent diabetes mellitus in a nationally representative sample of US adults. Materials and Methods: Data were pooled from five US Behavioral Ri…
View article: Epidemiological Insights into the Combined Associations of Physical Activity and BMI on the Prevalence of Chronic Disease: Analysis of 2.3 Million U.S. Adults from the Behavioral Risk Factor Surveillance System
Epidemiological Insights into the Combined Associations of Physical Activity and BMI on the Prevalence of Chronic Disease: Analysis of 2.3 Million U.S. Adults from the Behavioral Risk Factor Surveillance System Open
This thesis examined how physical activity (PA) and body mass index (BMI) are jointly associated with chronic disease, using data from over 2.3 million U.S. adults in the Behavioral Risk Factor Surveillance System (BRFSS). PA was more stro…
View article: Vitamin D did not reduce multiple sclerosis disease activity after a clinically isolated syndrome
Vitamin D did not reduce multiple sclerosis disease activity after a clinically isolated syndrome Open
Low serum levels of 25-hydroxyvitamin D [25(OH)D] and low sunlight exposure are known risk factors for the development of multiple sclerosis. Add-on vitamin D supplementation trials in established multiple sclerosis have been inconclusive.…
View article: 2359 Optimising patient selection for muscle biopsy in a general neurology setting
2359 Optimising patient selection for muscle biopsy in a general neurology setting Open
Objectives We aimed to assess the diagnostic utility of a muscle biopsy in a general neurology setting, and to identify strategies to improve patient selection. Methods The clinical records and histology reports of adult patients who under…
View article: MRI Patterns Distinguish AQP4 Antibody Positive Neuromyelitis Optica Spectrum Disorder From Multiple Sclerosis
MRI Patterns Distinguish AQP4 Antibody Positive Neuromyelitis Optica Spectrum Disorder From Multiple Sclerosis Open
Neuromyelitis optica spectrum disorder (NMOSD) and multiple sclerosis (MS) are inflammatory diseases of the CNS. Overlap in the clinical and MRI features of NMOSD and MS means that distinguishing these conditions can be difficult. With the…
View article: The latitude gradient for multiple sclerosis prevalence is established in the early life course
The latitude gradient for multiple sclerosis prevalence is established in the early life course Open
The strongest epidemiological clue that the environment at the population level has a significant impact on the risk of developing multiple sclerosis is the well established, and in many instances, increasing latitudinal gradient of preval…
View article: Testing Wearable UV Sensors to Improve Sun Protection in Young Adults at an Outdoor Festival: Field Study
Testing Wearable UV Sensors to Improve Sun Protection in Young Adults at an Outdoor Festival: Field Study Open
Background Australia and New Zealand have the highest skin cancer incidence rates worldwide, and sun exposure is the main risk factor for developing skin cancer. Sun exposure during childhood and adolescence is a critical factor in develop…
View article: Safety and acceptability of clozapine and risperidone in progressive multiple sclerosis: a phase I, randomised, blinded, placebo-controlled trial
Safety and acceptability of clozapine and risperidone in progressive multiple sclerosis: a phase I, randomised, blinded, placebo-controlled trial Open
Objective Because clozapine and risperidone have been shown to reduce neuroinflammation in humans and mice, the Clozapine and Risperidone in Progressive Multiple Sclerosis (CRISP) trial was conducted to determine whether clozapine and risp…
View article: Relapse Patterns in NMOSD: Evidence for Earlier Occurrence of Optic Neuritis and Possible Seasonal Variation
Relapse Patterns in NMOSD: Evidence for Earlier Occurrence of Optic Neuritis and Possible Seasonal Variation Open
Neuromyelitis optica spectrum disorders (NMOSD) and multiple sclerosis (MS) show overlap in their clinical features. We performed an analysis of relapses with the aim of determining differences between the two conditions. Cases of NMOSD an…
View article: Testing Wearable UV Sensors to Improve Sun Protection in Young Adults at an Outdoor Festival: Field Study (Preprint)
Testing Wearable UV Sensors to Improve Sun Protection in Young Adults at an Outdoor Festival: Field Study (Preprint) Open
BACKGROUND Australia and New Zealand have the highest skin cancer incidence rates worldwide, and sun exposure is the main risk factor for developing skin cancer. Sun exposure during childhood and adolescence is a critical factor in develo…
View article: Safety and acceptability of clozapine and risperidone in progressive multiple sclerosis: a phase 1, randomized, blinded, placebo-controlled trial
Safety and acceptability of clozapine and risperidone in progressive multiple sclerosis: a phase 1, randomized, blinded, placebo-controlled trial Open
Objective Because clozapine and risperidone have been shown to reduce neuroinflammation in humans and mice, the CRISP trial was conducted to determine whether clozapine and risperidone are suitable for progressive multiple sclerosis (pMS).…
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Issue Information Open
Cardiovascular Therapeutics (formerly Cardiovascular Drug Reviews) focuses on
View article: Issue Information
Issue Information Open
Cardiovascular Therapeutics (formerly Cardiovascular Drug Reviews) focuses on extensive reviews