Anthony S. David
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View article: Cognitive Behavior Therapy for Depersonalization-Derealization Disorder (CBT-f-DDD): a feasibility randomized trial
Cognitive Behavior Therapy for Depersonalization-Derealization Disorder (CBT-f-DDD): a feasibility randomized trial Open
Background Depersonalization-derealization disorder (DDD) is characterized by feelings of “unreality” about the self and/or external world. Cognitive Behavioral Therapy adapted for DDD (CBT-f-DDD) has been effective in published clinical a…
View article: Drivers of AI–Sustainability: The Roles of Financial Wealth, Human Capital, and Renewable Energy
Drivers of AI–Sustainability: The Roles of Financial Wealth, Human Capital, and Renewable Energy Open
Artificial Intelligence (AI) is increasingly central to sustainable development, yet its advancement varies across G7 economies. This study employs Method of Moments Quantile Regression (MMQR) to examine how Financial Technology (FinTech),…
View article: Temporal relationship between severe mental illness and neurological conditions in a UK primary care cohort
Temporal relationship between severe mental illness and neurological conditions in a UK primary care cohort Open
Background A higher prevalence of neurological conditions has been found in schizophrenia, bipolar disorder and other psychotic illnesses compared to the general population. We aimed to understand the cumulative prevalence of 15 neurologic…
View article: Increased Brain-Age Gap in Young Adults With Psychotic Experiences
Increased Brain-Age Gap in Young Adults With Psychotic Experiences Open
Background: Psychotic experiences (PEs) are linked to structural brain variation, but their relation to magnetic resonance imaging (MRI) derived brain-age is unclear. We hypothesized that young adults reporting PEs would show an increased …
View article: The Metabolome Atlas of 22 Tissues in Aging Mice Reveals a Switch in Thermogenesis from Brown Fat to Skeletal Muscle
The Metabolome Atlas of 22 Tissues in Aging Mice Reveals a Switch in Thermogenesis from Brown Fat to Skeletal Muscle Open
Aging impairs thermoregulatory capacity, yet the metabolic mechanisms remain unclear. We report an organ-resolved metabolome atlas of 2,875 structurally annotated metabolites of old (90-96 weeks) versus young mice (16 weeks) across 22 tiss…
View article: Protocol for a multi-country retrospective observational paediatric sepsis epidemiological study (SENTINEL International)
Protocol for a multi-country retrospective observational paediatric sepsis epidemiological study (SENTINEL International) Open
Introduction Improving outcomes from sepsis in children is a WHO Global Health Priority, yet mortality from sepsis remains high, particularly in low- and middle-income countries (LMICs). This database from children with community-acquired …
View article: The Effect of Developmental Trauma on Brain Structures Involved in Threat and Memory Processing and Its Relation to Psychotic Experiences in Adulthood
The Effect of Developmental Trauma on Brain Structures Involved in Threat and Memory Processing and Its Relation to Psychotic Experiences in Adulthood Open
Background and Hypothesis Despite growing evidence of a causal association between developmental trauma (DT) and psychotic experiences (PEs), the precise neurobiological mechanisms underlying this association remain poorly understood. We e…
View article: Cognition and metacognition in functional motor symptoms and functional seizures: A case-control study
Cognition and metacognition in functional motor symptoms and functional seizures: A case-control study Open
Summary Background Cognitive symptoms are common in functional neurological disorder (FND), yet there is inconsistent evidence of impaired neurocognitive test performance in this population. We aimed to assess core cognitive functions and …
View article: A Case-Control Study of Aetiological Factors in Functional Seizures and Functional Motor Symptoms: Shared and Distinct Features
A Case-Control Study of Aetiological Factors in Functional Seizures and Functional Motor Symptoms: Shared and Distinct Features Open
Background: Functional seizures (FS) and functional motor symptoms (FMS), subtypes of functional neurological disorder, may involve distinct predisposing, precipitating, perpetuating, and triggering (PPPT) factors. This study investigated …
View article: Reduced striatal dopamine transmission as a transdiagnostic substrate of psychomotor retardation
Reduced striatal dopamine transmission as a transdiagnostic substrate of psychomotor retardation Open
Psychomotor retardation, defined as generalized slowing of movement and speech, is a feature of several neurological and psychiatric disorders. In this review, we discuss the hypothesis that reduced striatal dopaminergic transmission is a …
View article: The role of the electroencephalogram (EEG) in determining the aetiology of psychosis: a systematic review and meta-analysis of diagnostic test accuracy
The role of the electroencephalogram (EEG) in determining the aetiology of psychosis: a systematic review and meta-analysis of diagnostic test accuracy Open
EEG demonstrates poor discrimination in identifying a secondary psychosis. Specific EEG abnormalities exhibit potential diagnostic value, encouraging more detailed reporting standards. While EEG alone does not definitively distinguish psyc…
View article: Influence of Computer Self-Efficacy, Socio Economic Status, and Facilitating Conditions on the Learning Abilities of Digital Arts Students
Influence of Computer Self-Efficacy, Socio Economic Status, and Facilitating Conditions on the Learning Abilities of Digital Arts Students Open
The learning landscape of digital arts has been transformed by the integration of digital technology into creative education. Disparities in students’ technological confidence, socio-economic backgrounds, and institutional support hinder e…
View article: Childhood Mild Traumatic Brain Injury is Reliably Associated with Anxiety but Not Other Examined Psychiatric Outcomes at Two‐Year Follow‐up, After Adjusting for Prior Mental Health
Childhood Mild Traumatic Brain Injury is Reliably Associated with Anxiety but Not Other Examined Psychiatric Outcomes at Two‐Year Follow‐up, After Adjusting for Prior Mental Health Open
Background Evidence that mild traumatic brain injury (mTBI) causes psychiatric problems in children has been mixed. Investigating this issue has been difficult due to the lack of representative longitudinal data that includes adequate meas…
View article: A national survey of neuropsychiatry training experiences
A national survey of neuropsychiatry training experiences Open
Aims and method Neuropsychiatry training in the UK currently lacks a formal scheme or qualification, and its demand and availability have not been systematically explored. We conducted the largest UK-wide survey of psychiatry trainees to e…
View article: Social Anxiety among University Undergraduates: The Influence of Mobile Gaming Addiction
Social Anxiety among University Undergraduates: The Influence of Mobile Gaming Addiction Open
Social anxiety (SA) significantly impacts university students, while mobile gaming addiction represents a growing concern with potential psychological consequences. Despite theoretical links, the specific influence of mobile gaming addicti…
Publisher Correction: Muscle abnormalities in Long COVID Open
Correction to: Nature Communicationshttps://doi.org/10.1038/s41467-025-56430-8, published online 11 February 2025 In the version of the article initially published, the title was incorrect (reading “Reply: Muscle abnormalities in Long COVI…
View article: Development and Validation of the Schedule for the Assessment of Insight in Anxiety Disorders (SAI‐A)
Development and Validation of the Schedule for the Assessment of Insight in Anxiety Disorders (SAI‐A) Open
There is a growing interest in understanding insight or illness awareness in anxiety; however, most assessment instruments were designed for psychosis. The unique features of anxiety highlight the need for tailored measures to accurately e…
View article: Genetic abnormalities in catatonia: a systematic review
Genetic abnormalities in catatonia: a systematic review Open
Background Catatonia has many potential underlying causes, but in some patients, no clear etiology is identified, sparking growing interest in its genetic basis. We aimed to provide the first comprehensive synthesis of genetic abnormalitie…
View article: Multiple Taxation and Performance of Selected SMEs in Edo Central, Edo State, Nigeria
Multiple Taxation and Performance of Selected SMEs in Edo Central, Edo State, Nigeria Open
This study is on effect of multiple taxation on the performance of selected SMEs in Edo Central, Edo State, Nigeria. The main objective is to determine the effect of multiple taxation on the performance of SMEs in Edo central while specifi…
View article: From Rags to Riches: the Fermentation Potential of Agave Leaf Residues in the Brazilian Semi-arid
From Rags to Riches: the Fermentation Potential of Agave Leaf Residues in the Brazilian Semi-arid Open
CAM plants are promising biomasses to assure energy security and biofuel supply in the current changing climate scenario. Their high sugar content and strengthened tolerance to high temperatures and droughts makes them attractive alternati…
View article: Real-time biopsychosocial antecedents and correlates of functional neurological symptoms in daily life: A pilot remote monitoring technology study
Real-time biopsychosocial antecedents and correlates of functional neurological symptoms in daily life: A pilot remote monitoring technology study Open
Functional neurological symptom disorder (FNSD) is a neuropsychiatric diagnosis referring to symptoms resembling those of neurological disorders, occurring without causal neuropathology. FNSD has a complex biopsychosocial aetiology but its…
View article: Effectiveness of antipsychotic drug therapy for treating psychosis in people with epilepsy: A systematic review
Effectiveness of antipsychotic drug therapy for treating psychosis in people with epilepsy: A systematic review Open
Individuals with epilepsy are at risk of developing preictal, ictal, postictal and interictal psychoses. Antipsychotic drugs (APDs) are the main class of drugs used to treat psychosis and schizophrenia. The efficacy and safety of APDs as a…