David C. Henderson
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View article: Bridging crisis and care: exploring the role of behavioral health professionals in a police co-response model
Bridging crisis and care: exploring the role of behavioral health professionals in a police co-response model Open
Police co-responder programs are collaborations between law enforcement and healthcare institutions where behavioral health professionals are embedded within police departments to support officers responding to incidents involving mental h…
View article: Adaptation of a PTSD intervention for use in primary care in a low-income country: The Brief Relaxation, Education and Trauma HEaling intervention for Ethiopia (BREATHE Ethiopia)
Adaptation of a PTSD intervention for use in primary care in a low-income country: The Brief Relaxation, Education and Trauma HEaling intervention for Ethiopia (BREATHE Ethiopia) Open
Posttraumatic Stress Disorder (PTSD) symptoms amongst people with serious mental illness (SMI) are prevalent in Ethiopia and throughout the world, yet treatment is scarce, particularly in low-resource settings with few mental health provid…
View article: Bridging Crisis and Care: Exploring the Role of Behavioral Health Professionals in a Police Co-Response Model
Bridging Crisis and Care: Exploring the Role of Behavioral Health Professionals in a Police Co-Response Model Open
Police co-responder programs are collaborations between law enforcement and healthcare institutions where behavioral health professionals are embedded within police departments to support officers responding to incidents involving mental h…
View article: Intimate partner violence related to disclosure of sickle cell disease during pregnancy: evidence from the sickle cell belt of central India
Intimate partner violence related to disclosure of sickle cell disease during pregnancy: evidence from the sickle cell belt of central India Open
Background Intimate partner violence (IPV) negatively impacts pregnant women and their unborn children. Globally, an estimated 19%, 9%, and 6% of women experience psychological, physical, and sexual IPV, respectively, during pregnancy. The…
View article: Making meaning through cultural embeddedness: Advancing culture‐sensitive training for Alzheimer’s Disease and Alzheimer’s Disease Related Dementia Caregivers in Ibadan, Nigeria
Making meaning through cultural embeddedness: Advancing culture‐sensitive training for Alzheimer’s Disease and Alzheimer’s Disease Related Dementia Caregivers in Ibadan, Nigeria Open
Background Limited knowledge exists about the cultural approaches to managing the psychological and behavioral outcomes (PBO) of Alzheimer’s Disease and Alzheimer’s Disease‐Related Dementia (AD/ADRD) in Africa. Specifically, to develop a c…
View article: Curriculum development in Liberia's first postgraduate psychiatry training programme
Curriculum development in Liberia's first postgraduate psychiatry training programme Open
This paper describes the implementation of curricula for Liberia's first-ever psychiatry training programme in 2019 and the actions of the only two Liberian psychiatrists in the country at the time in developing and executing a first-year …
View article: Validation of an ICD-code-based case definition for psychotic illness across three health systems
Validation of an ICD-code-based case definition for psychotic illness across three health systems Open
Background and Hypothesis Early detection of psychosis is critical for improving outcomes. Algorithms to predict or detect psychosis using electronic health record (EHR) data depend on the validity of the case definitions used, typically b…
View article: Social domains of poor mental health: A qualitative pilot study of community stakeholders’ understanding and demarcation of mental illness and its interpretations in rural Nigeria
Social domains of poor mental health: A qualitative pilot study of community stakeholders’ understanding and demarcation of mental illness and its interpretations in rural Nigeria Open
Background and Aims Although previous studies on mental health/illness in Nigeria have explored knowledge and attitude of community members using quantitative approaches, few studies have engaged stakeholders within rural communities on th…
View article: Building a postgraduate psychiatry training program in Liberia through cross-country collaborations: initiation stages, challenges, and opportunities
Building a postgraduate psychiatry training program in Liberia through cross-country collaborations: initiation stages, challenges, and opportunities Open
Background About 80% of the nearly 2 billion people experiencing psychiatric conditions worldwide do not have access to quality, affordable mental health care. In Africa, there are 0.004 psychiatrists per 10,000 people, with the shortage e…
View article: Gone Too Soon: priorities for action to prevent premature mortality associated with mental illness and mental distress
Gone Too Soon: priorities for action to prevent premature mortality associated with mental illness and mental distress Open
Globally, too many people die prematurely from suicide and the physical comorbidities associated with mental illness and mental distress. The purpose of this Review is to mobilise the translation of evidence into prioritised actions that r…
View article: Long-Term Trends in Psychiatric Emergency Services Delivered by the Boston Emergency Services Team
Long-Term Trends in Psychiatric Emergency Services Delivered by the Boston Emergency Services Team Open
View article: A Global-Local Paradigm for Mental Health: A Model and Implications for Addressing Disparities Through Training and Research
A Global-Local Paradigm for Mental Health: A Model and Implications for Addressing Disparities Through Training and Research Open
View article: Experiences and practices of caregiving for older persons living with dementia in African countries: A qualitative scoping review
Experiences and practices of caregiving for older persons living with dementia in African countries: A qualitative scoping review Open
Background The increasing awareness and diagnosis of dementia in Africa necessitate documentation of caregiving practices to understand local patterns and improve the quality of care. Caregiving in African communities is rooted in informal…
View article: Development of the South Sudan Mental Health Assessment Scale
Development of the South Sudan Mental Health Assessment Scale Open
This study developed and validated a measure that captures variation in common local idioms of distress and mental health problems experienced by women in South Sudan, a country which has experienced over 50 years of violence, displacement…
View article: Prevalence of metabolic syndrome among patients with schizophrenia in Ethiopia
Prevalence of metabolic syndrome among patients with schizophrenia in Ethiopia Open
Background Globally, the prevalence of metabolic syndrome (MetS) is higher among patients with schizophrenia than the general population, and this leads to higher morbidity and mortality in this population. The aim of this study was to inv…
View article: Exploration of alcohol use disorder-associated brain miRNA–mRNA regulatory networks
Exploration of alcohol use disorder-associated brain miRNA–mRNA regulatory networks Open
View article: Towards a better understanding of attitudes and beliefs held by traditional healers and recipients of traditional medicine concerning mental health conditions in post-conflict Liberia: a qualitative investigation
Towards a better understanding of attitudes and beliefs held by traditional healers and recipients of traditional medicine concerning mental health conditions in post-conflict Liberia: a qualitative investigation Open
Background: A better understanding of attitudes and beliefs held by traditional healers and utilizers of traditional medicine concerning mental health conditions in Liberia is important as Liberia seeks to improve its delivery of mental he…
View article: Psychotherapy in a resource-constrained setting: Understanding context for adapting and integrating a brief psychological intervention into primary care.
Psychotherapy in a resource-constrained setting: Understanding context for adapting and integrating a brief psychological intervention into primary care. Open
Low- and middle-income countries have few mental health professionals, and efforts to increase access to treatment are a global priority. A key gap is the lack of integration of psychotherapy interventions as a part of accessible evidence-…
View article: Exploration of alcohol use disorder-associated brain miRNA-mRNA regulatory networks
Exploration of alcohol use disorder-associated brain miRNA-mRNA regulatory networks Open
Alcohol use disorder (AUD) is due to gene expression changes in specific brain regions, but the underlying mechanism is not fully understood. We investigated AUD-associated miRNA-mRNA regulatory networks in multiple brain regions by analyz…
View article: Treatment Effect With Paliperidone Palmitate Compared With Oral Antipsychotics in Black/African American Patients With Schizophrenia and a History of Criminal Justice System Involvement
Treatment Effect With Paliperidone Palmitate Compared With Oral Antipsychotics in Black/African American Patients With Schizophrenia and a History of Criminal Justice System Involvement Open
ClinicalTrials.gov identifier: NCT01157351.
View article: Global mental health: the role of collaboration during the COVID-19 pandemic
Global mental health: the role of collaboration during the COVID-19 pandemic Open
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View article: Analysis of telomere length variation and Shelterin complex subunit gene expression changes in ethanol-exposed human embryonic stem cells
Analysis of telomere length variation and Shelterin complex subunit gene expression changes in ethanol-exposed human embryonic stem cells Open
View article: Using local terminology to measure substance use behaviors among youth in post-conflict Liberia: a mixed methods study
Using local terminology to measure substance use behaviors among youth in post-conflict Liberia: a mixed methods study Open
This mixed methods study aimed to use local terminology to accurately characterize the prevalence and risk factors associated with substance use and risky health behaviors among school-based youth in Monrovia, Liberia. An 86-question surve…
View article: Current state of the literature on mental health in Liberia: A systematic review
Current state of the literature on mental health in Liberia: A systematic review Open
Background: The Republic of Liberia recently experienced several events that resulted in wide-ranging societal impacts, including long-term civil war and an outbreak of Ebola. These types of events are linked to higher prevalence of mental…
View article: The effects of eszopiclone on sleep spindles and memory consolidation in schizophrenia: a randomized clinical trial
The effects of eszopiclone on sleep spindles and memory consolidation in schizophrenia: a randomized clinical trial Open
View article: Establishing reliability and validity for mental health screening instruments in resource-constrained settings: Systematic review of the PHQ-9 and key recommendations
Establishing reliability and validity for mental health screening instruments in resource-constrained settings: Systematic review of the PHQ-9 and key recommendations Open
View article: Prefrontal cortex eQTLs/mQTLs enriched in genetic variants associated with alcohol use disorder and other diseases
Prefrontal cortex eQTLs/mQTLs enriched in genetic variants associated with alcohol use disorder and other diseases Open
Aim: This study aimed to investigate the function of genome-wide association study (GWAS)-identified variants associated with alcohol use disorder (AUD)/comorbid psychiatric disorders. Materials & methods: Genome-wide genotyp…
View article: Traumatic loss and psychosis – reconceptualising the role of trauma in psychosis
Traumatic loss and psychosis – reconceptualising the role of trauma in psychosis Open
Literature suggests that the occurrence of psychological trauma (PT) from various negative life experiences beyond events mentioned in the DSM-criterion A, receives little to no attention when comorbid with psychosis. In fact, despite rese…
View article: Psychometric Validation of a Novel PRO MEASURE for Assessing Patient-reported Experience of Cognitive Impairment in Schizophrenia (PRECIS)
Psychometric Validation of a Novel PRO MEASURE for Assessing Patient-reported Experience of Cognitive Impairment in Schizophrenia (PRECIS) Open
Background Cognitive impairment associated with schizophrenia (CIAS) can be a distressing feature that contributes to the burden of the disorder, as well as being a strong predictor of functional impairment. To fully assess the burden to p…
View article: The African Global Mental Health Institute: Increasing capacity, inclusivity and translation of psychiatric research and care
The African Global Mental Health Institute: Increasing capacity, inclusivity and translation of psychiatric research and care Open
The largest treatment gap for mental, neurological and substance use (MNS) disorders to date exists in Sub-Saharan Africa (e.g., South Africa, Malawi, Nigeria). While efforts have been made to reduce the global burden of MNS disorders, the…