David C. Poskitt
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View article: Production of Monoclonal Anti‐Idiotype Antibodies Which Mimic an M‐Like Protein of <i>Streptococcus equi</i>
Production of Monoclonal Anti‐Idiotype Antibodies Which Mimic an M‐Like Protein of <i>Streptococcus equi</i> Open
Rat monoclonal anti‐idiotype antibodies (mAb2) were raised against two mouse monoclonal antibodies (mAb1), 1D10 and 2A6, with specificity for the M‐like protein of Streptococcus equi. The capacity of the mAb2 to inhibit the binding between…
View article: The nature of immunoglobulin idiotypes and idiotype‐anti‐idiotype interactions in immunological networks
The nature of immunoglobulin idiotypes and idiotype‐anti‐idiotype interactions in immunological networks Open
The nature of immunoglobulin idiotypes and idiotype-anti-idiotype interactions in immunological networks
View article: The migration of blood-borne lymphocytes into rat popliteal lymph nodes stimulated with xenogeneic red blood cells.
The migration of blood-borne lymphocytes into rat popliteal lymph nodes stimulated with xenogeneic red blood cells. Open
The recruitment of radiolabelled blood-borne lymphocytes into rat popliteal lymph nodes (PLN) was investigated following the injection of varying doses of chicken (CRBC) or sheep red blood cells (SRBC) into the hind foot pad. Within the do…
View article: The appearance of non-specific antibody-forming cells in the efferent lymph draining antigen-stimulated single lymph nodes.
The appearance of non-specific antibody-forming cells in the efferent lymph draining antigen-stimulated single lymph nodes. Open
Immunization of single lymph nodes with various antigens led to the appearance of cells in the efferent lymph that secreted antibody specific for the antigen which induced their formation and for a number of unrelated, non-crossreacting an…
View article: Two distinct pools of recirculating T lymphocytes: migratory characteristics of nodal and intestinal T lymphocytes.
Two distinct pools of recirculating T lymphocytes: migratory characteristics of nodal and intestinal T lymphocytes. Open
A pronounced asymmetry in the recirculation from blood to lymph of resting small recirculating T lymphocytes is described. When 51Cr-labeled small T-recirculating lymphocytes (TRL) from intestinal lymph were infused intravenously their rel…
View article: Antipolysaccharide antibodies of restricted heterogeneity secreted by a single lymph node
Antipolysaccharide antibodies of restricted heterogeneity secreted by a single lymph node Open
Immune responses which give rise to the synthesis of antibodies of restricted heterogeneity can be reproducibly induced in rabbits and mice by streptococcal polysaccharide antigens (1,2). While these reports have demonstrated clonotype res…