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View article: Simulating asteroid impacts and meteor events by high-power lasers: from the laboratory to spaceborne missions
Simulating asteroid impacts and meteor events by high-power lasers: from the laboratory to spaceborne missions Open
Meteor plasmas and impact events are complex, dynamic natural phenomena. Simulating these processes in the laboratory is, however, a challenge. The technique of laser induced dielectric breakdown was first used for this purpose almost 50 y…
View article: Statistical evaluation of character support reveals the instability of higher-level dinosaur phylogeny
Statistical evaluation of character support reveals the instability of higher-level dinosaur phylogeny Open
The interrelationships of the three major dinosaur clades (Theropoda, Sauropodomorpha, and Ornithischia) have come under increased scrutiny following the recovery of conflicting phylogenies by a large new character matrix and its extensive…
View article: Palliative care practice and moral distress during COVID-19 pandemic (PEOpLE-C19 study): a national, cross-sectional study in intensive care units in the Czech Republic
Palliative care practice and moral distress during COVID-19 pandemic (PEOpLE-C19 study): a national, cross-sectional study in intensive care units in the Czech Republic Open
Background Providing palliative care at the end of life (EOL) in intensive care units (ICUs) seems to be modified during the COVID-19 pandemic with potential burden of moral distress to health care providers (HCPs). We seek to assess the p…
View article: Comprehensive taxon sampling and vetted fossils help clarify the time tree of shorebirds (Aves, Charadriiformes)
Comprehensive taxon sampling and vetted fossils help clarify the time tree of shorebirds (Aves, Charadriiformes) Open
Shorebirds (Charadriiformes) are a globally distributed clade of modern birds and, due to their ecological and morphological disparity, a frequent subject of comparative studies. While molecular phylogenies have been instrumental to resolv…
View article: Age and just allocation of resources
Age and just allocation of resources Open
Tento článek se zabývá problémem alokace zdrojů v kontextu stárnutí lidské populace.Nejdříve se zaměřuje na konkrétní příklad alokace vzácných zdrojů během pandemie covid-19 a ukazuje, jakou roli během ní hraje věk pacientů.Posléze přecház…
View article: Meteorit Potůčky (Steinbach): historie a nové nálezy (Česká republika)
Meteorit Potůčky (Steinbach): historie a nové nálezy (Česká republika) Open
In the years 2017 and 2019 two silicate-rich iron meteorites (IVA-an) with a total weight of over 7 kg were found during the collection of rock samples near the old mining locality Glücksburg near Potůčky in the Krušné hory/Erzgebirge Moun…
View article: How virtue signalling makes us better: Moral preferences with respect to autonomous vehicle type choices
How virtue signalling makes us better: Moral preferences with respect to autonomous vehicle type choices Open
Autonomous vehicles (henceforth AVs) are about to be introduced to the mass market. However, many moral questions concerning AVs still remain. One of the issues has to do with the choice between AV types that differ in their built-in algor…
View article: Loss of Sodium/Hydrogen Exchanger NHA2 Exacerbates Obesity- and Aging-Induced Glucose Intolerance in Mice
Loss of Sodium/Hydrogen Exchanger NHA2 Exacerbates Obesity- and Aging-Induced Glucose Intolerance in Mice Open
We previously demonstrated that the sodium/hydrogen exchanger NHA2, also known as NHEDC2 or SLC9B2, is critical for insulin secretion by β-cells. To gain more insights into the role of NHA2 on systemic glucose homeostasis, we studied the i…
View article: Prevention of vascular dysfunction and arterial hypertension in mice generated by assisted reproductive technologies by addition of melatonin to culture media
Prevention of vascular dysfunction and arterial hypertension in mice generated by assisted reproductive technologies by addition of melatonin to culture media Open
Assisted reproductive technologies (ART) induce vascular dysfunction in humans and mice. In mice, ART-induced vascular dysfunction is related to epigenetic alteration of the endothelial nitric oxide synthase (eNOS) gene, resulting in decre…