David D. Pascoe
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Synthesis of 2,6-<i>trans</i>-Tetrahydropyrans Using a Palladium-Catalyzed Oxidative Heck Redox-Relay Strategy Open
The C-aryl-tetrahydropyran motif is prevalent in nature in a number of natural products with biological activity; however, this challenging architecture still requires novel synthetic approaches. We demonstrate the application of a stereos…
View article: Concurrent Exercise Training: Long-Term Changes in Body Composition and Motives for Continued Participation in Women with Obesity
Concurrent Exercise Training: Long-Term Changes in Body Composition and Motives for Continued Participation in Women with Obesity Open
The purpose of this project was to examine the effect of a concurrent exercise program (sprint interval training and resistance exercise) on body composition in women with obesity and factors associated with continued exercise participatio…
View article: A study of the reactivity of cyclic aminomethylammonium mannich salts
A study of the reactivity of cyclic aminomethylammonium mannich salts Open
A novel method for the preparation of aminoalkylaminomethyl products was developed utilising novel Mannich-type salts featuring a R2NCH2NR3+ moiety. This methodology showed good nucleophile scope and was successfully employed in reactions …
The Effect of a Sprint Interval and Resistance Training Program on Body Composition, Aerobic Fitness, and Self-regulation in Young Women Open
Background: Exercise has positive effects on overall health and reduces risk for several chronic diseases. Diverse program modalities are growing as a potential intervention to improve physiological and psychological outcomes. Purpose: The…
View article: Functional Performance of Firefighters After Exposure to Environmental Conditions and Exercise
Functional Performance of Firefighters After Exposure to Environmental Conditions and Exercise Open
Context Slips, trips, and falls are leading causes of musculoskeletal injuries in firefighters. Researchers have hypothesized that heat stress is the major contributing factor to these fireground injuries. Objective To examine the effect o…
View article: Unilateral application of an external pneumatic compression therapy improves skin blood flow and vascular reactivity bilaterally
Unilateral application of an external pneumatic compression therapy improves skin blood flow and vascular reactivity bilaterally Open
Background We sought to determine the effects of unilateral lower-limb external pneumatic compression (EPC) on bilateral lower-limb vascular reactivity and skin blood flow. Methods Thirty-two participants completed this two-aim study. In A…
View article: Peer Review #1 of "Unilateral application of an external pneumatic compression therapy improves skin blood flow and vascular reactivity bilaterally (v0.1)"
Peer Review #1 of "Unilateral application of an external pneumatic compression therapy improves skin blood flow and vascular reactivity bilaterally (v0.1)" Open
Background:We sought to determine the effects of unilateral lower-limb external pneumatic compression (EPC) on bilateral lower-limb vascular reactivity and skin blood flow.Methods: Thirty-two completed this two-aim study.In AIM1 (n=18, age…
Red Spinach Extract Increases Ventilatory Threshold during Graded Exercise Testing Open
Background: We examined the acute effect of a red spinach extract (RSE) (1000 mg dose; ~90 mg nitrate (NO 3 − )) on performance markers during graded exercise testing (GXT). Methods: For this randomized, double-blind, placebo (PBO)-control…
Effects of Whey, Soy or Leucine Supplementation with 12 Weeks of Resistance Training on Strength, Body Composition, and Skeletal Muscle and Adipose Tissue Histological Attributes in College-Aged Males Open
We sought to determine the effects of L-leucine (LEU) or different protein supplements standardized to LEU (~3.0 g/serving) on changes in body composition, strength, and histological attributes in skeletal muscle and adipose tissue. Sevent…
Molecular, neuromuscular, and recovery responses to light versus heavy resistance exercise in young men Open
Recent evidence suggests that resistance training with light or heavy loads to failure results in similar adaptations. Herein, we compared how both training modalities affect the molecular, neuromuscular, and recovery responses following e…
Does external pneumatic compression treatment between bouts of overreaching resistance training sessions exert differential effects on molecular signaling and performance-related variables compared to passive recovery? An exploratory study Open
EPC mitigated a reduction in flexibility and PPT that occurred with sham. Moreover, EPC reduced select skeletal muscle oxidative stress and proteolysis markers during recovery from heavy resistance exercise.
Does External Pneumatic Compression Treatment Between Bouts Of Overreaching Resistance Training Sessions Exert Differential Effects On Molecular Signaling And Performance-Related Variables Compared To Passive Recovery? An Exploratory Study Open
Supplemental Information: Data set respective to manuscript published in PLOS ONE titled "Does external pneumatic compression treatment between bouts of overreaching resistance training sessions exert differential effects on molecular sign…
Does External Pneumatic Compression Treatment Between Bouts Of Overreaching Resistance Training Sessions Exert Differential Effects On Molecular Signaling And Performance-Related Variables Compared To Passive Recovery? An Exploratory Study Open
Supplemental Information: Data set respective to manuscript published in PLOS ONE titled "Does external pneumatic compression treatment between bouts of overreaching resistance training sessions exert differential effects on molecular sign…
Effects of a pre-workout supplement on hyperemia following leg extension resistance exercise to failure with different resistance loads Open
Compared to PBO, the PWS consumed herein augmented hyperemia following multiple sets to failure at 80% of 1-RM, but not 30%. This specificity may be a product of interaction with local perturbations (e.g., reduced tissue oxygenation levels…
Impact of external pneumatic compression target inflation pressure on transcriptome-wide RNA expression in skeletal muscle Open
Next-generation RNA sequencing was employed to determine the acute and subchronic impact of peristaltic pulse external pneumatic compression (PEPC) of different target inflation pressures on global gene expression in human vastus lateralis…
Dataset for: Impact of external pneumatic compression target inflation pressure on transcriptome-wide RNA expression in skeletal muscle Open
Next generation RNA sequencing was employed to determine the acute and sub-chronic impact of peristaltic pulse external pneumatic compression (PEPC) of different target inflation pressures on global gene expression in human vastus laterali…
Evaluation of 2 Heat-Mitigation Methods in Army Trainees Open
Context: Heat injury is a significant threat to military trainees. Different methods of heat mitigation are in use across military units. Mist fans are 1 of several methods used in the hot and humid climate of Fort Benning, Georgia. Object…
View article: Proceedings of the Thirteenth International Society of Sports Nutrition (ISSN) Conference and Expo
Proceedings of the Thirteenth International Society of Sports Nutrition (ISSN) Conference and Expo Open
Meeting Abstracts: Proceedings of the Thirteenth International Society of Sports Nutrition (ISSN) Conference and Expo Clearwater Beach, FL, USA. 9-11 June 2016