David E. Jacobs
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View article: Housing as a social determinant of health: a contemporary framework
Housing as a social determinant of health: a contemporary framework Open
Housing is a key social determinant of health. Healthy housing is affordable, suitable, and secure. It is characterised by warmth, dryness, and proper ventilation; free from hazards such as mould and toxins; accessible to occupants with fu…
View article: Unbounded: A Generative Infinite Game of Character Life Simulation
Unbounded: A Generative Infinite Game of Character Life Simulation Open
We introduce the concept of a generative infinite game, a video game that transcends the traditional boundaries of finite, hard-coded systems by using generative models. Inspired by James P. Carse's distinction between finite and infinite …
View article: Magic Insert: Style-Aware Drag-and-Drop
Magic Insert: Style-Aware Drag-and-Drop Open
We present Magic Insert, a method for dragging-and-dropping subjects from a user-provided image into a target image of a different style in a physically plausible manner while matching the style of the target image. This work formalizes th…
View article: IEUBK Modeling of Children’s Blood Lead Levels in Homes Served by Private Domestic Wells in Three Illinois Counties
IEUBK Modeling of Children’s Blood Lead Levels in Homes Served by Private Domestic Wells in Three Illinois Counties Open
Lead is known to impair neurocognitive development in children. Drinking water is routinely monitored for lead content in municipal systems, but private well owners are not required to test for lead. The lack of testing poses a risk of lea…
View article: RealFill: Reference-Driven Generation for Authentic Image Completion
RealFill: Reference-Driven Generation for Authentic Image Completion Open
Recent advances in generative imagery have brought forth outpainting and inpainting models that can produce high-quality, plausible image content in unknown regions. However, the content these models hallucinate is necessarily inauthentic,…
View article: Energy Savings With Acceptable Indoor Air Quality Through Improved Airflow Control in Residential Retrofits
Energy Savings With Acceptable Indoor Air Quality Through Improved Airflow Control in Residential Retrofits Open
The Partnership for Advanced Residential Retrofit (PARR) has been a U.S. Department of Energy (DOE) Building America team since 2009, with a primary focus on upgrading the performance of existing buildings to reduce energy loads. In this p…
View article: Review of the Impact of Housing Quality on Inequalities in Health and Well-Being
Review of the Impact of Housing Quality on Inequalities in Health and Well-Being Open
Housing quality is essential for population health and broader well-being. The World Health Organization Housing and health guidelines highlight interventions that protect occupants from cold and hot temperatures, injuries, and other hazar…
View article: Childhood Lead Poisoning 1970-2022: Charting Progress and Needed Reforms
Childhood Lead Poisoning 1970-2022: Charting Progress and Needed Reforms Open
Context: Childhood lead poisoning prevention in the United States was marked by a largely failed medical approach from 1971 to 1990; an emergent (but small) healthy housing primary prevention strategy from 1991 to 2015; and implementation …
View article: Immediate-release/extended-release amantadine (OS320) to treat Parkinson's disease with levodopa-induced dyskinesia: Analysis of the randomized, controlled ALLAY-LID studies
Immediate-release/extended-release amantadine (OS320) to treat Parkinson's disease with levodopa-induced dyskinesia: Analysis of the randomized, controlled ALLAY-LID studies Open
BackgroundImmediate-release (IR) amantadine has been used for treatment of levodopa induced dyskinesia (LID). The immediate-release/extended-release (IR/ER) amantadine formulation OS320 (OSMOLEX ER®) contains an IR outer layer and ER core …
View article: Deep Saliency Prior for Reducing Visual Distraction
Deep Saliency Prior for Reducing Visual Distraction Open
Using only a model that was trained to predict where people look at images, and no additional training data, we can produce a range of powerful editing effects for reducing distraction in images. Given an image and a mask specifying the re…
View article: Predictors of Water Lead Levels in Drinking Water of Homes With Domestic Wells in 3 Illinois Counties
Predictors of Water Lead Levels in Drinking Water of Homes With Domestic Wells in 3 Illinois Counties Open
Context: Millions of US homes receive water from private wells, which are not required to be tested for lead (Pb). An approach to prioritizing high-risk homes for water lead level (WLL) testing may help focus outreach and screening efforts…
View article: Residential Dust Lead Levels and the Risk of Childhood Lead Poisoning in United States Children
Residential Dust Lead Levels and the Risk of Childhood Lead Poisoning in United States Children Open
Background and Aim: The United States Environmental Protection Agency (EPA) recently lowered the residential dust lead hazard standards for floors and windowsills from 40 to 10 μg/ft2 and 250 to 100 μg/ft2, respectively, while maintaining …
View article: Early life lead exposure and behavioral problems among children in the HOME Study
Early life lead exposure and behavioral problems among children in the HOME Study Open
Background: Lead exposure is associated with behavioral problems in children, but the ages when children are most susceptible to lead toxicity are unclear. Our objective was to evaluate the association of repeated blood lead concentrations…
View article: Building Assessment of Radon Reduction Interventions with Energy Retrofits Expansion (The BEX Study): Final Report
Building Assessment of Radon Reduction Interventions with Energy Retrofits Expansion (The BEX Study): Final Report Open
This report presents the findings from a study that was performed to assess whether current precautionary measures used by the US Department of Energy Weatherization Assistance Program (WAP) are effective for preventing indoor radon increa…
View article: Portrait shadow manipulation
Portrait shadow manipulation Open
Casually-taken portrait photographs often suffer from unflattering lighting and shadowing because of suboptimal conditions in the environment. Aesthetic qualities such as the position and softness of shadows and the lighting ratio between …
View article: Portrait Shadow Manipulation
Portrait Shadow Manipulation Open
Casually-taken portrait photographs often suffer from unflattering lighting and shadowing because of suboptimal conditions in the environment. Aesthetic qualities such as the position and softness of shadows and the lighting ratio between …
View article: LEAD IN HOMES WITH DOMESTIC WELLS IN THREE ILLINOIS COUNTIES
LEAD IN HOMES WITH DOMESTIC WELLS IN THREE ILLINOIS COUNTIES Open
Lead in drinking water has recently become a national concern on account of the leaching of lead from old water mains and service lines by corrosive water. The Lead and Copper Rule (LCR) requires public water supplies to test the quality o…
View article: Ten questions concerning the implications of carpet on indoor chemistry and microbiology
Ten questions concerning the implications of carpet on indoor chemistry and microbiology Open
Carpet and rugs currently represent about half of the United States flooring market and offer many benefits as a flooring type. How carpets influence our exposure to both microorganisms and chemicals in indoor environments has important he…
View article: Bioavailability and Pharmacokinetics of Once-Daily Amantadine Extended-Release Tablets in Healthy Volunteers: Results from Three Randomized, Crossover, Open-Label, Phase 1 Studies
Bioavailability and Pharmacokinetics of Once-Daily Amantadine Extended-Release Tablets in Healthy Volunteers: Results from Three Randomized, Crossover, Open-Label, Phase 1 Studies Open
Osmotica Pharmaceutical US LLC.
View article: Effects of Renal Impairment on the Pharmacokinetics of Once-Daily Amantadine Extended-Release Tablets
Effects of Renal Impairment on the Pharmacokinetics of Once-Daily Amantadine Extended-Release Tablets Open
Renal impairment was associated with reduced amantadine clearance. Based on pharmacokinetic modeling and simulations, dose regimens were recommended for subjects with impaired renal function to provide systemic amantadine exposure similar …
View article: Lead Poisoning in Private and Public Housing: The Legacy Still Before Us
Lead Poisoning in Private and Public Housing: The Legacy Still Before Us Open
AffiliationsThe author is with the National Center for Healthy Housing, Columbia, MD, and the School of Public Health, University of Illinois at Chicago.
View article: Effect of Residential Lead-Hazard Interventions on Childhood Blood Lead Concentrations and Neurobehavioral Outcomes
Effect of Residential Lead-Hazard Interventions on Childhood Blood Lead Concentrations and Neurobehavioral Outcomes Open
ClinicalTrials.gov identifier: NCT00129324.
View article: Synthetic depth-of-field with a single-camera mobile phone
Synthetic depth-of-field with a single-camera mobile phone Open
Shallow depth-of-field is commonly used by photographers to isolate a subject from a distracting background. However, standard cell phone cameras cannot produce such images optically, as their short focal lengths and small apertures captur…
View article: Home Rx: The Health Benefits of Home Performance
Home Rx: The Health Benefits of Home Performance Open
Evidence in a new, groundbreaking U.S. Department of Energy report, Home Rx: The Health Benefits of Home Performance, shows that home performance upgrades can improve the quality of a home’s indoor environment by reducing the prevalence of…