David Edholm
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View article: Omental preservation <i>versus</i> omentectomy in curative-intent gastrectomy for gastric cancer: Swedish population-based cohort study
Omental preservation <i>versus</i> omentectomy in curative-intent gastrectomy for gastric cancer: Swedish population-based cohort study Open
Background Omentectomy has traditionally been performed in gastric cancer surgery, but omental preservation has become increasingly common. It is unclear whether omentectomy leads to additional survival benefit compared with omental preser…
View article: Inter-rater variability in multidisciplinary team meetings of oesophageal and gastro-oesophageal junction cancer on staging, resectability and treatment recommendation: national retrospective multicentre study
Inter-rater variability in multidisciplinary team meetings of oesophageal and gastro-oesophageal junction cancer on staging, resectability and treatment recommendation: national retrospective multicentre study Open
Background There are differences in oesophageal cancer care across Sweden. According to national guidelines, all patients should be offered equal care, planned and administrated by regional multidisciplinary team meetings. The aim of the s…
View article: 417. POSTOPERATIVE CHYLE LEAK - LESS LIKELY IN OBESE PATIENTS AND ASSOCIATED WITH POSTOPERATIVE MORTALITY
417. POSTOPERATIVE CHYLE LEAK - LESS LIKELY IN OBESE PATIENTS AND ASSOCIATED WITH POSTOPERATIVE MORTALITY Open
Background Esophagectomy can be complicated by postoperative chyle leak (PCL). PCL is a rare condition but accounts for considerable morbidity and can be challenging to manage. Predisposing factors and the impact of PCL on survival are not…
View article: 784. NO SUPPORT FOR IMMEDIATE POSTOPERATIVE REMOVAL OF NASOGASTRIC TUBE AFTER ESOPHAGECTOMY, RESULTS FROM A NORDIC MULTICENTER RANDOMIZED CONTROLLED TRIAL
784. NO SUPPORT FOR IMMEDIATE POSTOPERATIVE REMOVAL OF NASOGASTRIC TUBE AFTER ESOPHAGECTOMY, RESULTS FROM A NORDIC MULTICENTER RANDOMIZED CONTROLLED TRIAL Open
Background Esophagectomy is central in curative treatment of esophageal and gastroesophageal junctional cancer. Postoperative nasogastric (NG) tube for drainage of the gastric conduit is routine in most centers. The NG tube is typically as…
View article: 474. SELF EXPANDABLE METAL STENT AS A BRIDGE TO RESECTION IN ESOPHAGEAL CANCER – A NATIONAL REGISTER ANALYSIS ON MORTALITY
474. SELF EXPANDABLE METAL STENT AS A BRIDGE TO RESECTION IN ESOPHAGEAL CANCER – A NATIONAL REGISTER ANALYSIS ON MORTALITY Open
Background Patients with esophageal cancer commonly present with malnutrition and weight loss due to dysphagia. Self Expandable Metal Stent (SEMS) have been used to relieve dysphagia and optimize nutrition prior to surgery and during neoad…
View article: 286. TREATMENT WITH CURATIVE INTENT FOR OLIGOMETASTATIC GASTROESOPHAGEAL CANCER-RESULTS OF A PROSPECTIVE MULTICENTER STUDY
286. TREATMENT WITH CURATIVE INTENT FOR OLIGOMETASTATIC GASTROESOPHAGEAL CANCER-RESULTS OF A PROSPECTIVE MULTICENTER STUDY Open
Background Oligometastatic gastroesophageal cancer is a clinical entity with no standard treatment recommendation. Treatment with curative intent has recently emerged as an option in selected patients in contrast to the traditional palliat…
View article: Multidisciplinary team meetings improve survival in patients with esophageal cancer
Multidisciplinary team meetings improve survival in patients with esophageal cancer Open
Summary Multidisciplinary team meetings (MDTs) are recommended for patients with esophageal cancer. Improved staging, timeliness to surgery and better adherence to guidelines have been attributed to MDTs, but there are few studies publishe…
View article: 71658 - Postoperative chyle leak – Less likely in obese patients and associated with postoperative mortality
71658 - Postoperative chyle leak – Less likely in obese patients and associated with postoperative mortality Open
Introduction Esophagectomy can be complicated by postoperative chyle leak (PCL). PCL is rare and can be challenging to manage. Predisposing factors and the impact of PCL on survival are not fully understood. This study aimed to investigate…
View article: Randomized controlled trial of nasogastric tube use after esophagectomy: study protocol for the kinetic trial
Randomized controlled trial of nasogastric tube use after esophagectomy: study protocol for the kinetic trial Open
Summary Esophagectomy is a complex and complication laden procedure. Despite centralization, variations in perioparative strategies reflect a paucity of evidence regarding optimal routines. The use of nasogastric (NG) tubes post esophagect…
View article: Very low risk of short bowel after Roux-en-Y gastric bypass – a large nationwide Swedish cohort study
Very low risk of short bowel after Roux-en-Y gastric bypass – a large nationwide Swedish cohort study Open
The study included 57,255 patients having undergone RYGB. Closure of the mesenteric openings was performed in 78%. Surgery for SBO was required in 3659 (6%) of patients, and small bowel resection in 188 (.3%). Extensive small bowel resecti…
View article: 301. DIFFERENCES IN MULTIDISCIPLINARY CANCER CONFERENCES OF ESOPHAGEAL AND GASTROESOPHAGEAL JUNCTIONAL CANCER REGARDING STAGING AND TREATMENT ALLOCATION—A MULTICENTER STUDY
301. DIFFERENCES IN MULTIDISCIPLINARY CANCER CONFERENCES OF ESOPHAGEAL AND GASTROESOPHAGEAL JUNCTIONAL CANCER REGARDING STAGING AND TREATMENT ALLOCATION—A MULTICENTER STUDY Open
Background There are differences in esophageal cancer care across different regions in Sweden. According to Swedish national guidelines, all patients diagnosed with these tumors should be individually evaluated by regional multidisciplinar…
View article: 163. ESOPHAGEAL PERFORATIONS – A POPULATION-BASED NATIONWIDE STUDY IN SWEDEN WITH SURVIVAL ANALYSIS
163. ESOPHAGEAL PERFORATIONS – A POPULATION-BASED NATIONWIDE STUDY IN SWEDEN WITH SURVIVAL ANALYSIS Open
Esophageal perforation is a rare and life-threatening condition with several treatment options. The aim was to assess the incidence, type of treatment and mortality of esophageal perforations in Sweden and to identify risk factors for 90-d…
View article: Neoadjuvant Chemoradiotherapy and Surgery for Esophageal Squamous Cell Carcinoma Versus Definitive Chemoradiotherapy With Salvage Surgery as Needed: The Study Protocol for the Randomized Controlled NEEDS Trial
Neoadjuvant Chemoradiotherapy and Surgery for Esophageal Squamous Cell Carcinoma Versus Definitive Chemoradiotherapy With Salvage Surgery as Needed: The Study Protocol for the Randomized Controlled NEEDS Trial Open
Background The globally dominant treatment with curative intent for locally advanced esophageal squamous cell carcinoma (ESCC) is neoadjuvant chemoradiotherapy (nCRT) with subsequent esophagectomy. This multimodal treatment leads to around…
View article: Esophageal perforations – a population-based nationwide study in Sweden with survival analysis
Esophageal perforations – a population-based nationwide study in Sweden with survival analysis Open
90-day mortality was 26%, old age, vascular disease and underlying malignant disease were risk factors.
View article: Obstruction after Sleeve Gastrectomy, Prevalence, and Interventions: a Cohort Study of 9,726 Patients with Data from the Scandinavian Obesity Surgery Registry (SOReg)
Obstruction after Sleeve Gastrectomy, Prevalence, and Interventions: a Cohort Study of 9,726 Patients with Data from the Scandinavian Obesity Surgery Registry (SOReg) Open
Background Sleeve gastrectomy (SG) is the most common bariatric procedure worldwide. Obstructive symptoms, together with leaks, are among the most serious postoperative complications. This study aimed to investigate the incidence of sympto…
View article: Outcome of microscopically non-radical oesophagectomy for oesophageal and oesophagogastric junctional cancer: nationwide cohort study
Outcome of microscopically non-radical oesophagectomy for oesophageal and oesophagogastric junctional cancer: nationwide cohort study Open
Background Microscopically non-radical (R1) oesophageal cancer resection has been associated with worse survival. The aim of this study was to identify risk factors for R1 resection and to investigate how this affects long-term survival. M…
View article: Burden of in-hospital care in oesophageal cancer: national population-based study
Burden of in-hospital care in oesophageal cancer: national population-based study Open
Background Oesophageal cancer management requires extensive in-hospital care. This cohort study aimed to quantify in-hospital care for patients with oesophageal cancer in relation to intended treatment, and to analyse factors associated wi…
View article: Complications and survival after hybrid and fully minimally invasive oesophagectomy
Complications and survival after hybrid and fully minimally invasive oesophagectomy Open
Background Minimally invasive oesophagectomy (MIO) is reported to produce fewer respiratory complications than open oesophagectomy. This study assessed differences in postoperative complications between MIO and hybrid MIO (HMIO) employing …
View article: Abandoning resectional intent in patients initially deemed suitable for esophagectomy: a nationwide study of risk factors and outcomes
Abandoning resectional intent in patients initially deemed suitable for esophagectomy: a nationwide study of risk factors and outcomes Open
Summary The main curative treatment modality for esophageal cancer is resection. Patients initially deemed suitable for resection may become unsuitable, most commonly due to signs of generalized disease or having become unfit for surgery. …
View article: Acute caloric restriction counteracts hepatic bile acid and cholesterol deficiency in morbid obesity
Acute caloric restriction counteracts hepatic bile acid and cholesterol deficiency in morbid obesity Open
Background Bile acid ( BA ) synthesis is regulated by BA signalling in the liver and by fibroblast growth factor 19 ( FGF 19), synthesized and released from the intestine. In morbid obesity, faecal excretion and hepatic synthesis of BA s a…
View article: Laparoscopy in Duodenal Switch: Safe and Halves Length of Stay in a Nationwide Cohort from the Scandinavian Obesity Registry
Laparoscopy in Duodenal Switch: Safe and Halves Length of Stay in a Nationwide Cohort from the Scandinavian Obesity Registry Open
Background and Aims: Unsatisfactory weight loss after gastric bypass or sleeve gastrectomy in super-obese patients (body mass index > 50) is a growing concern. Biliopancreatic diversion with duodenal switch results in greater weight loss, …