David Ehrlich
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View article: Direct cerebellar control over motor production in a species with extreme cerebellar enlargement
Direct cerebellar control over motor production in a species with extreme cerebellar enlargement Open
Summary The cerebellum is thought to fine-tune movement without being required for its production. However, this textbook view derives mainly from studies of mammalian species with highly developed cerebral cortices. Here we examined cereb…
View article: Evolutionarily conserved brainstem architecture enables gravity-guided vertical navigation
Evolutionarily conserved brainstem architecture enables gravity-guided vertical navigation Open
The sensation of gravity anchors our perception of the environment and is important for navigation. However, the neural circuits that transform gravity into commands for navigation are undefined. We first determined that larval zebrafish (…
View article: A brainstem circuit for gravity-guided vertical navigation
A brainstem circuit for gravity-guided vertical navigation Open
The sensation of gravity anchors our perception of the environment and is crucial for navigation. However, the neural circuits that transform gravity into commands for navigation are undefined. We first determined that larval zebrafish ( D…
View article: Lightning Pose dataset: mirror-fish
Lightning Pose dataset: mirror-fish Open
Weakly-electric Mormyrid fish (of the species Gnathonemus petersii) swim freely in and out of an experimental tank, capturing worms from a well. The tank has a side mirror and a top mirror, both at 45◦, providing three different views seen…
View article: Behavioral control through the direct, focal silencing of neuronal activity
Behavioral control through the direct, focal silencing of neuronal activity Open
Voltage-gated sodium channel (Na V ) activity underlies electrical signaling, synaptic release, circuit function, and, ultimately, behavior. Molecular tools that enable precise control of Na V subpopulations make possible temporal regulati…
View article: Hatchling fish disperse using an efficient multisensory strategy
Hatchling fish disperse using an efficient multisensory strategy Open
Animals improve fitness by choosing when and where to disperse in the environment using sensory cues. In freshwater habitats subject to flood and drought, dispersal can urgently challenge newly hatched fish. Here we manipulated rearing env…
View article: How To Start a Grassroots Movement
How To Start a Grassroots Movement Open
We study the influence of social messages that promote a digital public good, a COVID-19 tracing app. We vary whether subjects receive a digital message from another subject, and, if so, at what cost it came. Observed maximum willingness t…
View article: A primal role for the vestibular sense in the development of coordinated locomotion
A primal role for the vestibular sense in the development of coordinated locomotion Open
Mature locomotion requires that animal nervous systems coordinate distinct groups of muscles. The pressures that guide the development of coordination are not well understood. To understand how and why coordination might emerge, we measure…
View article: A primal role for balance in the development of coordinated locomotion
A primal role for balance in the development of coordinated locomotion Open
Mature locomotion requires that animal nervous systems coordinate distinct groups of muscles. The pressures that guide the development of coordination are not well understood. We studied vertical locomotion in developing zebrafish to under…
View article: A novel mechanism for volitional locomotion in larval zebrafish
A novel mechanism for volitional locomotion in larval zebrafish Open
To locomote stably, animals must coordinate volitional actions that change posture with opposing reflexes that hold posture constant [1–8]. These conflicting actions are thought to necessitate integrated control, in which reflexes are modu…
View article: Control of Movement Initiation Underlies the Development of Balance
Control of Movement Initiation Underlies the Development of Balance Open
Balance arises from the interplay of external forces acting on the body and internally generated movements. Many animal bodies are inherently unstable, necessitating corrective locomotion to maintain stability. Understanding how developing…