David González Calle
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View article: Left atrial appendage closure in patients with prior intracranial bleeding, safety, efficacy, and timing
Left atrial appendage closure in patients with prior intracranial bleeding, safety, efficacy, and timing Open
Left atrial appendage occlusion is an effective and safe treatment alternative to reduce the risk of ischemic stroke in selected patients with atrial fibrillation and prior intracranial hemorrhage. In this study, we did not find difference…
View article: Inclisiran: Efficacy in Real World—Systematic Review and Meta-Analysis
Inclisiran: Efficacy in Real World—Systematic Review and Meta-Analysis Open
Background: Inclisiran is a novel lipid-lowering agent targeting PCSK9 via small interfering RNA (siRNA) technology. While clinical trials such as the ORION studies have demonstrated significant reductions in low-density lipoprotein choles…
View article: Left atrial appendage closure in patients with prior intracranial bleeding, safety, efficacy, and timing
Left atrial appendage closure in patients with prior intracranial bleeding, safety, efficacy, and timing Open
View article: Clinical utility and safety of finerenone in patients with heart failure: Rationale and design of FINE registry
Clinical utility and safety of finerenone in patients with heart failure: Rationale and design of FINE registry Open
Aims Information about current use of finerenone in patients with heart failure (HF) finerenone in clinical practice is scarce, and its effectiveness in clinical practice in patients is scarce. We aim to assess both the baseline clinical p…
View article: SCAI SHOCK stage classification: valid for all indications and devices in patients with short-term mechanical circulatory support?
SCAI SHOCK stage classification: valid for all indications and devices in patients with short-term mechanical circulatory support? Open
Funding Acknowledgements None. Background The Society for Cardiovascular Angiography and Intervention (SCAI) SHOCK stage has demonstrated prognostic value in patients with cardiogenic shock (CS), including patients on venoarterial extracor…
View article: Predicting survival with scales for in-hospital extracorporeal cardiopulmonary resuscitation
Predicting survival with scales for in-hospital extracorporeal cardiopulmonary resuscitation Open
Funding Acknowledgements None. Background Extracorporeal cardiopulmonary resuscitation (ECPR) is a rescue option in cardiac arrest (CA) refractory to advanced life support. Patient selection is challenging, and anecdotal scores are specifi…
View article: Endometriosis at the level of uterine isthmocele: Case report
Endometriosis at the level of uterine isthmocele: Case report Open
An isthmocele is a reservoir-type defect in the fornix of the cul-de-sac in the anterior wall of the isthmus at the site of the previous cesarean scar. It’s appearance is related to the accumulation of menstrual blood flow through the cerv…
View article: Molecular Diagnosis as an Alternative for Public Health Surveillance of Leptospirosis in Colombia
Molecular Diagnosis as an Alternative for Public Health Surveillance of Leptospirosis in Colombia Open
Leptospirosis represents a public health problem in Colombia. However, the underreporting of the disease is an unfortunate reality, with a clear trend towards a decrease in cases since 2019, when the guidelines for its confirmatory diagnos…
View article: Left appendage closure after intracranial hemorrhage: safety, efficacy and timing
Left appendage closure after intracranial hemorrhage: safety, efficacy and timing Open
Background Oral anticoagulation (OAC) use increases the risk of intracranial hemorrhage (ICH) in patients with atrial fibrillation (AF). Left atrial appendage occlusion (LAAO) is an alternative to OAC, however data about its use in patient…
View article: Safety and procedural success of left appendage closure interventions with transesophageal echocardiography microprobes
Safety and procedural success of left appendage closure interventions with transesophageal echocardiography microprobes Open
Introduction Transesophageal echocardiography (TOE) is the most frequently used imaging technique for intraprocedural guidance in left appendage closure interventions. However, it usually requires the use general anaesthesia and implies an…
View article: Prognostic factors and mortality predictive scale in patients treated with in-hospital extracorporeal cardiopulmonary resuscitation
Prognostic factors and mortality predictive scale in patients treated with in-hospital extracorporeal cardiopulmonary resuscitation Open
Background Extracorporeal cardiopulmonary resuscitation (ECPR) is a rescue option in cardiac arrest (CA) refractory to advanced life support. Patient selection is challenging, evidence is limited and randomized studies are lacking regardin…
View article: Effectiveness and Safety of an Outpatient Program for Percutaneous Left Atrial Appendage Occlusion
Effectiveness and Safety of an Outpatient Program for Percutaneous Left Atrial Appendage Occlusion Open
Background: Left atrial appendage occlusion (LAAO) is a safe and effective alternative to oral anticoagulation for thromboprophylaxis in patients with nonvalvular atrial fibrillation. Technological development in devices and imaging techni…
View article: Relationship between the structure, function and endothelial damage, and vascular ageing and the biopsychological situation in adults diagnosed with persistent COVID (BioICOPER study). A research protocol of a cross-sectional study
Relationship between the structure, function and endothelial damage, and vascular ageing and the biopsychological situation in adults diagnosed with persistent COVID (BioICOPER study). A research protocol of a cross-sectional study Open
Background: SARS-CoV-2 infection affects the vascular endothelium, which mediates the inflammatory and thrombotic cascade. Moreover, alterations in the endothelium are related to arterial stiffness, which has been established as a marker o…
View article: Prophylaxis and treatment of nosocomial infections in patients under short-term mechanical circulatory support
Prophylaxis and treatment of nosocomial infections in patients under short-term mechanical circulatory support Open
Funding Acknowledgements Type of funding sources: None. Background Infections are frequent in patients requiring short-term mechanical circulatory support (MCS). The definition and diagnosis of infection is complex and variable, antibiotic…
View article: Nosocomial infections in patients requiring short-term mechanical circulatory support: characteristics, risk factors and prognosis
Nosocomial infections in patients requiring short-term mechanical circulatory support: characteristics, risk factors and prognosis Open
Funding Acknowledgements Type of funding sources: None. Background The use of short-term mechanical circulatory support (MCS) has been increasing in recent years. Infection is a frequent complications and seems to contribute to increased m…
View article: The heart and SARS-CoV-2
The heart and SARS-CoV-2 Open
View article: Differential electrocardiographic changes related to the culprit coronary artery in patients with acute myocardial infarction and left bundle branch block
Differential electrocardiographic changes related to the culprit coronary artery in patients with acute myocardial infarction and left bundle branch block Open
Background The electrocardiographic (ECG) recognition of acute myocardial infarction (AMI) in patients with concurrent left bundle branch block (LBBB) is hampered by background changes in QRS complex duration and ST segment, potential dire…
View article: Corazón y SARS-CoV-2
Corazón y SARS-CoV-2 Open
View article: The Spanish medical specialist training perception of the COVID-19 pandemic impact in their emotional health and training, a cross-sectional observational study
The Spanish medical specialist training perception of the COVID-19 pandemic impact in their emotional health and training, a cross-sectional observational study Open
Specialist training in Spain is conceptualized as a dual system regulated as both a public employment and a graduate training program. Due to the global pandemic created by COVID-19 which hit Spain in March 2020, the Spanish specialist tra…
View article: Afección pericárdica y miocárdica tras infección por SARS-CoV-2: estudio descriptivo transversal en trabajadores sanitarios
Afección pericárdica y miocárdica tras infección por SARS-CoV-2: estudio descriptivo transversal en trabajadores sanitarios Open
View article: Cierre percutáneo de orejuela izquierda tras hemorragia intracraneal: ¿cuándo realizarlo?
Cierre percutáneo de orejuela izquierda tras hemorragia intracraneal: ¿cuándo realizarlo? Open
[ES] Introducción La anticoagulación oral es el tratamiento por excelencia para la prevención de eventos embólicos en pacientes con fibrilación auricular, arritmia cardiaca más prevalente en nuestro medio. Su uso conlleva un incremento del…
View article: Pericardial and myocardial involvement after SARS-CoV-2 infection: a cross-sectional descriptive study in healthcare workers
Pericardial and myocardial involvement after SARS-CoV-2 infection: a cross-sectional descriptive study in healthcare workers Open
View article: Retrospective Identification of Early Autochthonous Case of Crimean-Congo Hemorrhagic Fever, Spain, 2013
Retrospective Identification of Early Autochthonous Case of Crimean-Congo Hemorrhagic Fever, Spain, 2013 Open
Before this report, 7 autochthonous human cases of Crimean-Congo hemorrhagic fever had been reported in Spain, all occurring since 2016. We describe the retrospective identification of an eighth case dating back to 2013. This study highlig…
View article: Left atrial appendage occlusion: a decade of evidence
Left atrial appendage occlusion: a decade of evidence Open
Over the last few years, left atrial appendage occlusion (LAAO) has gained traction in patients with nonvalvular atrial fibrillation as an alternative to oral anticoagulation to prevent cerebral infarction, especially in patients with some…
View article: Cierre percutáneo de la orejuela izquierda: una década de evidencias
Cierre percutáneo de la orejuela izquierda: una década de evidencias Open
El cierre percutáneo de la orejuela izquierda (COI) se ha establecido en los últimos años, en los pacientes con fibrilación auricular no valvular, como una alternativa a la anticoagulación oral para la prevención del infarto cerebral, en e…
View article: Functional mitral regurgitation in dilated cardiomyopathy: clinical implications and prognosis
Functional mitral regurgitation in dilated cardiomyopathy: clinical implications and prognosis Open
Funding Acknowledgements Type of funding sources: None. Dilated cardiomyopathy (DCM) is a complex myocardial disease, with a high burden of symptoms and decreased life expectancy. Mitral regurgitation (MR) is a frequent comorbid condition …
View article: Survival with low- and high-flux dialysis
Survival with low- and high-flux dialysis Open
Background Besides advances in haemodialysis (HD), mortality rates are still high. The effect of the different types of HD membranes on survival is still a controversial issue. The aim of this COSMOS (Current management Of Secondary hyperp…
View article: Remote ischemic preconditioning ameliorates anthracycline-induced cardiotoxicity and preserves mitochondrial integrity: results from a randomized preclinical trial in pigs
Remote ischemic preconditioning ameliorates anthracycline-induced cardiotoxicity and preserves mitochondrial integrity: results from a randomized preclinical trial in pigs Open
Introduction Anthracycline-induced cardiotoxicity (AIC) is a serious adverse effect occurring in a significant proportion of patients. Irreversible mitochondrial damage is a central mechanism of AIC. Despite many efforts, there is a lack o…
View article: Hemorragia espontánea de origen incierto
Hemorragia espontánea de origen incierto Open
La hemofilia A adquirida es un trastorno infrecuente de la coagulación debido a autoanticuerpos frente al factor VIII. Se debe sospechar en caso de sangrado espontáneo y prolongación del TTPA. Presentamos el caso de un varón de 85 años con…
View article: Coronavirus Disease 2019 Intermediate Care Units: Containing Escalation of ICUs
Coronavirus Disease 2019 Intermediate Care Units: Containing Escalation of ICUs Open
To the Editor: According to the recent publications of Sauro et al (1) and Co and Hyzy (2) in Critical Care Medicine, a crucial moment in the care of severely ill patients is the transition from the ICUs to ordinary hospitalization wards, …