David Sánchez-Migallón Guzman
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View article: SAT-234 Hepatotoxic Effects of HFPO Homologues in Mice: Evaluating the Safety of PFOA and PFOS Replacements
SAT-234 Hepatotoxic Effects of HFPO Homologues in Mice: Evaluating the Safety of PFOA and PFOS Replacements Open
Disclosure: M. La Merrill: None. D. Guzman: None. M.L. Goodson: None. B. Lachter: None. A. Ehrlich: None. Presentation Type: Traditional Poster Presentation (Printed Poster)Science Type and Topic: Basic Scientific Research Authors: David G…
View article: SAT-243 Assessment of PFAS ‘Forever Chemicals’ on Viability of Triple-Negative Breast Cancer Cells
SAT-243 Assessment of PFAS ‘Forever Chemicals’ on Viability of Triple-Negative Breast Cancer Cells Open
Disclosure: M. La Merrill: None. D. Guzman: None. S. Singh Johal: None. B.J. Mengeling: None. Abstract Body: Per- and polyfluoroalkyl substances (PFAS) are pervasive environmental pollutants found in household items such as non-stick cookw…
View article: Pharmacokinetics of single-dose oral acetaminophen with and without concurrent administration of silymarin or N-acetylcysteine in orange-winged Amazon parrots (Amazona amazonica)
Pharmacokinetics of single-dose oral acetaminophen with and without concurrent administration of silymarin or N-acetylcysteine in orange-winged Amazon parrots (Amazona amazonica) Open
Objective To determine the pharmacokinetics of acetaminophen ( N -acetyl-para-aminophenol [APAP]) and its metabolites after oral administration of a single dose of APAP, with or without silymarin or N -acetylcysteine (NAC), to orange-winge…
View article: Chlamydial infections in free-ranging raptors presenting to a university veterinary medical teaching hospital (1993–2022)
Chlamydial infections in free-ranging raptors presenting to a university veterinary medical teaching hospital (1993–2022) Open
OBJECTIVE To describe the prevalence, clinical findings, lesions, and risk factors associated with chlamydial infections in free-ranging raptors presented to a university veterinary medical teaching hospital. METHODS Medical records retros…
View article: Kirschner wire creates more microdamage than standard or acrylic drill bits in the rabbit (Oryctolagus cuniculi) femur
Kirschner wire creates more microdamage than standard or acrylic drill bits in the rabbit (Oryctolagus cuniculi) femur Open
OBJECTIVE Histologically evaluate damage to rabbit femur after the creation of bicortical 1.5-mm-diameter holes using a standard surgical drill bit, an acrylic drill bit, and a Kirschner wire (K-wire). METHODS 10 femora (5 pairs) from skel…
View article: Delays and inequalities in breast cancer in Meta Colombia (2017–2023): A cross-sectional study
Delays and inequalities in breast cancer in Meta Colombia (2017–2023): A cross-sectional study Open
View article: The pharmacokinetics of single-dose oral atorvastatin and its metabolites support therapeutic use in cockatiels (Nymphicus hollandicus)
The pharmacokinetics of single-dose oral atorvastatin and its metabolites support therapeutic use in cockatiels (Nymphicus hollandicus) Open
OBJECTIVE To evaluate the plasma concentrations and determine the pharmacokinetic parameters of atorvastatin and its primary active metabolites (para- and orthohydroxyatorvastatin) after administration of a single oral dose in cockatiels (…
View article: K-wire is more damaging than standard or acrylic drill bits when evaluating torsional properties of rabbit (Oryctolagus cuniculi) femurs
K-wire is more damaging than standard or acrylic drill bits when evaluating torsional properties of rabbit (Oryctolagus cuniculi) femurs Open
OBJECTIVE The objective of this study is to compare drilling variables and torsional mechanical properties of rabbit femora after bicortical drilling with a 1.5-mm standard surgical drill bit, acrylic drill bit, and K-wire. SAMPLES 24 pair…
View article: Cardiovascular disease in central bearded dragons (Pogona vitticeps): 54 cases (2007–2022)
Cardiovascular disease in central bearded dragons (Pogona vitticeps): 54 cases (2007–2022) Open
OBJECTIVE To describe the clinical features, histopathologic lesions, and outcome of cardiovascular disease in central bearded dragons. ANIMALS 54 bearded dragons. METHODS Retrospective evaluation of captive bearded dragons with antemortem…
View article: Pharmacokinetics of single-dose oral atorvastatin and its metabolites support therapeutic use in orange-winged Amazon parrots (Amazona amazonica)
Pharmacokinetics of single-dose oral atorvastatin and its metabolites support therapeutic use in orange-winged Amazon parrots (Amazona amazonica) Open
OBJECTIVE To evaluate the plasma concentrations and determine pharmacokinetic parameters of atorvastatin and its primary active metabolites (para- and ortho-hydroxyatorvastatin) after administration of a single oral dose in orange-winged A…
View article: Carrageenan-induced inflammation elicits behavioral changes in cockatiels (Nymphicus hollandicus) for potential pain scale development
Carrageenan-induced inflammation elicits behavioral changes in cockatiels (Nymphicus hollandicus) for potential pain scale development Open
OBJECTIVE To evaluate behaviors associated with inflammatory pain induced by carrageenan injection in the cockatiel and determine interobserver agreement. ANIMALS 16 adult cockatiels. METHODS Cockatiels were randomly assigned as either tre…
View article: High bioavailability, short half-life, and metabolism into hydromorphone-3-glucuronide following single intramuscular and intravenous administration of hydromorphone hydrochloride to great horned owls (Bubo virginianus)
High bioavailability, short half-life, and metabolism into hydromorphone-3-glucuronide following single intramuscular and intravenous administration of hydromorphone hydrochloride to great horned owls (Bubo virginianus) Open
OBJECTIVE To determine the pharmacokinetic parameters of hydromorphone hydrochloride and its metabolite, hydromorphone-3-glucuronide (H3G), after a single IV and IM dose in great horned owls ( Bubo virginianus ). ANIMALS 6 healthy adult gr…
View article: Twice-daily oral administration of a cannabidiol and cannabidiolic acid–rich hemp extract was well tolerated in orange-winged Amazon parrots (Amazona amazonica) and has a favorable pharmacokinetic profile
Twice-daily oral administration of a cannabidiol and cannabidiolic acid–rich hemp extract was well tolerated in orange-winged Amazon parrots (Amazona amazonica) and has a favorable pharmacokinetic profile Open
OBJECTIVE To determine the pharmacokinetics of 8 cannabinoids and 5 metabolites after oral administration of single and multiple doses of a cannabidiol (CBD)-cannabidiolic acid (CBDA)–rich hemp extract to orange-winged Amazon parrots ( Ama…
View article: Pharmacokinetics of maropitant citrate in Rhode Island Red chickens (<i>Gallus gallus domesticus</i>) following subcutaneous administration
Pharmacokinetics of maropitant citrate in Rhode Island Red chickens (<i>Gallus gallus domesticus</i>) following subcutaneous administration Open
Maropitant citrate is a synthetic neurokinin‐1 receptor antagonist and substance P inhibitor used for control of emesis in dogs in cats. Maropitant citrate is used empirically in birds, despite a lack of pharmacokinetic data in avian speci…
View article: Pharmacokinetics of butorphanol tartrate in a poloxamer P407 gel formulation administered to orange-winged Amazon parrots (Amazona amazonica)
Pharmacokinetics of butorphanol tartrate in a poloxamer P407 gel formulation administered to orange-winged Amazon parrots (Amazona amazonica) Open
OBJECTIVES To determine the pharmacokinetics of butorphanol tartrate incorporated into poloxamer 407 (P407) after subcutaneous administration to orange-winged Amazon parrots ( Amazona amazonica ). ANIMALS Six orange-winged Amazon parrots, …
View article: Evaluation of weight-bearing, locomotion, thermal antinociception, and footpad size in a carrageenan-induced inflammatory model in the cockatiel (Nymphicus hollandicus)
Evaluation of weight-bearing, locomotion, thermal antinociception, and footpad size in a carrageenan-induced inflammatory model in the cockatiel (Nymphicus hollandicus) Open
OBJECTIVES To evaluate a carrageenan-induced inflammatory model in the cockatiel ( Nymphicus hollandicus ) using weight-bearing load, rotational perch locomotion, thermal threshold withdrawal, and footpad dimensions. ANIMALS 16 adult cocka…
View article: Pharmacokinetics of pimobendan following oral administration to New Zealand White rabbits (Oryctolagus cuniculus)
Pharmacokinetics of pimobendan following oral administration to New Zealand White rabbits (Oryctolagus cuniculus) Open
OBJECTIVE To determine the pharmacokinetics and potential adverse effects of pimobendan after oral administration in New Zealand White rabbits ( Ocytolagus cuniculi ). ANIMALS 10 adult sexually intact (5 males and 5 females) rabbits. PROCE…
View article: Diagnosis and treatment of Candida glabrata proventriculitis in an eclectus parrot (Eclectus roratus)
Diagnosis and treatment of Candida glabrata proventriculitis in an eclectus parrot (Eclectus roratus) Open
CASE DESCRIPTION An 8-year-old sexually intact female eclectus parrot ( Eclectus roratus ) with a 4-day history of hyporexia and lethargy and a 1-day history of tenesmus was examined. CLINICAL FINDINGS Severe leukocytosis characterized by …
View article: Survival Analysis and Influence of the Surgical Aggression of a Cohort of Orthopedic and Trauma Patients in a Non-controlled Spread COVID-19 Scenario
Survival Analysis and Influence of the Surgical Aggression of a Cohort of Orthopedic and Trauma Patients in a Non-controlled Spread COVID-19 Scenario Open
Background: During the coronavirus disease pandemic, determining the impact of elective and urgent orthopedic and trauma surgeries (OTS) on the infection rate and mortality probability can guide the preparations for next waves. The purpose…
View article: Varying Expression of Mu and Kappa Opioid Receptors in Cockatiels (Nymphicus hollandicus) and Domestic Pigeons (Columba livia domestica)
Varying Expression of Mu and Kappa Opioid Receptors in Cockatiels (Nymphicus hollandicus) and Domestic Pigeons (Columba livia domestica) Open
The differential expression of opioid receptors between cockatiels and pigeons could have implications for variability in analgesic response between these two species.
View article: Genomes of Three Closely Related Caribbean Amazons Provide Insight for Species History and Conservation
Genomes of Three Closely Related Caribbean Amazons Provide Insight for Species History and Conservation Open
Islands have been used as model systems for studies of speciation and extinction since Darwin published his observations about finches found on the Galapagos. Amazon parrots inhabiting the Greater Antillean Islands represent a fascinating …
View article: Differential Disease Susceptibilities in Experimentally Reptarenavirus-Infected Boa Constrictors and Ball Pythons
Differential Disease Susceptibilities in Experimentally Reptarenavirus-Infected Boa Constrictors and Ball Pythons Open
Inclusion body disease (IBD) is an infectious disease originally described in captive snakes. It has traditionally been diagnosed by the presence of large eosinophilic cytoplasmic inclusions and is associated with neurological, gastrointes…
View article: Renal, gastrointestinal, and hemostatic effects of oral administration of meloxicam to Hispaniolan Amazon parrots (Amazona ventralis)
Renal, gastrointestinal, and hemostatic effects of oral administration of meloxicam to Hispaniolan Amazon parrots (Amazona ventralis) Open
OBJECTIVE To investigate renal, gastrointestinal, and hemostatic effects associated with oral administration of multiple doses of meloxicam to healthy Hispaniolan Amazon parrots ( Amazona ventralis ). ANIMALS 12 Hispaniolan Amazon parrots.…