Byung‐Soo Kim
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View article: Cellf-Deception: Human microglia clone 3 (HMC3) cells exhibit more astrocyte-like than microglia-like gene expression
Cellf-Deception: Human microglia clone 3 (HMC3) cells exhibit more astrocyte-like than microglia-like gene expression Open
Recent advances in Alzheimer’s research suggest that the brain’s immune system plays a critical role in the development and progression of this devastating disease. Microglial cells are vital as immune cells in the brain’s defense system. …
View article: Self-Powered Ultraviolet-C Imaging Using Epitaxial Gallium Oxide Membranes with Anisotropic Domain Conduction
Self-Powered Ultraviolet-C Imaging Using Epitaxial Gallium Oxide Membranes with Anisotropic Domain Conduction Open
High efficiency of charge carrier conduction is crucial for photoelectrical performance in ultraviolet C (UVC) photodetectors (PDs) based on heteroepitaxial beta-gallium oxide (β-Ga2O3) thin films. However, the presence of in-plane rotatio…
View article: Sodium Phosphate-Induced Acute Phosphate Nephropathy after Colonoscopy: A Case Report
Sodium Phosphate-Induced Acute Phosphate Nephropathy after Colonoscopy: A Case Report Open
Acute phosphate nephropathy is caused by exposure to excess sodium phosphate. Calcium phosphate is deposited in the renal tubular epithelial cells, leading to tubulointerstitial nephritis. We report the case of a 71-year-old female who dev…
View article: The latest milestone in WOLED technology for OLED TV and IT displays: Enhancing efficiency, color gamut, and longevity
The latest milestone in WOLED technology for OLED TV and IT displays: Enhancing efficiency, color gamut, and longevity Open
This study introduces recent innovative progress in white organic light emitting diode (WOLED) technology for premium OLED TV and IT displays. By fabricating a four‐stack tandem device consisting of red, first blue, green, and second blue …
View article: Odronextamab monotherapy in patients with relapsed/refractory diffuse large B cell lymphoma: primary efficacy and safety analysis in phase 2 ELM-2 trial
Odronextamab monotherapy in patients with relapsed/refractory diffuse large B cell lymphoma: primary efficacy and safety analysis in phase 2 ELM-2 trial Open
The phase 2, multicohort, ongoing ELM-2 study evaluates odronextamab, a CD20×CD3 bispecific antibody, in patients with relapsed/refractory (R/R) B cell non-Hodgkin lymphoma after ≥2 lines of therapy. Here primary analysis of the diffuse la…
View article: Association between the cumulative excessive systolic blood pressure and left ventricular mass index
Association between the cumulative excessive systolic blood pressure and left ventricular mass index Open
Background Ambulatory blood pressure (ABP) has been increasingly adopted in day-to-day clinical practices. Although clinicians can access an enormous amount of information regarding an individual’s blood pressures (BPs) through the ABP mon…
View article: Engineered Nanoparticles for Enhanced Antitumoral Synergy Between Macrophages and T Cells in the Tumor Microenvironment
Engineered Nanoparticles for Enhanced Antitumoral Synergy Between Macrophages and T Cells in the Tumor Microenvironment Open
T cells and macrophages have the potential to collaborate to eliminate tumor cells efficiently. Macrophages can eliminate tumor cells through phagocytosis and subsequently activate T cells by presenting tumor antigens. The activated T cell…
View article: Molecular tools for recording and intervention of neuronal activity
Molecular tools for recording and intervention of neuronal activity Open
Observing the activity of neural networks is critical for the identification of learning and memory processes, as well as abnormal activities of neural circuits in disease, particularly for the purpose of tracking disease progression. Meth…
View article: Risk stratification for early mortality in newly diagnosed acute promyelocytic leukemia: a multicenter, non-selected, retrospective cohort study
Risk stratification for early mortality in newly diagnosed acute promyelocytic leukemia: a multicenter, non-selected, retrospective cohort study Open
Introduction Despite the current effective treatments for acute promyelocytic leukemia (APL), early mortality (EM), defined as death within 30 days of presentation, is a major hurdle to long-term survival. Methods We performed a multicente…
View article: <b>Strategies to Overcome Hurdles in Cancer Immunotherapy</b>
<b>Strategies to Overcome Hurdles in Cancer Immunotherapy</b> Open
Despite marked advancements in cancer immunotherapy over the past few decades, there remains an urgent need to develop more effective treatments in humans. This review explores strategies to overcome hurdles in cancer immunotherapy, levera…
View article: The development of therapeutic nanovaccine that elicits anti‐Aβ antibodies and Aβ‐specific regulatory T cells for the treatment of Alzheimer’s disease.
The development of therapeutic nanovaccine that elicits anti‐Aβ antibodies and Aβ‐specific regulatory T cells for the treatment of Alzheimer’s disease. Open
Background Alzheimer’s disease (AD) is a multi‐factorial cognitive disorder with complex pathogenesis including the accumulation of beta‐amyloid (Aβ) plaque and neuroinflammation. In previous studies, active immunotherapy injecting Aβ pept…
View article: Reduced Proliferation and Cell Death of Acute Myeloid Leukemia Cell Lines after Acalabrutinib Treatment
Reduced Proliferation and Cell Death of Acute Myeloid Leukemia Cell Lines after Acalabrutinib Treatment Open
Background Acute myeloid leukemia (AML) still remains a significant challenge, with intensive chemotherapy treatments showing limited efficacy and lack of druggable targets in contrast to other hematologic malignancies. Exosomes, nanomolec…
View article: Regulation of Interfacial Anchoring Orientation of Anisotropic Nanodumbbells
Regulation of Interfacial Anchoring Orientation of Anisotropic Nanodumbbells Open
Nanoparticles exhibiting geometrical and chemical anisotropies hold promise for environmentally responsive materials with tunable mechanical properties. However, a comprehensive understanding of their interfacial behaviors remains elusive.…
View article: Implementation of Field-Programmable Gate Array Platform for Object Classification Tasks Using Spike-Based Backpropagated Deep Convolutional Spiking Neural Networks
Implementation of Field-Programmable Gate Array Platform for Object Classification Tasks Using Spike-Based Backpropagated Deep Convolutional Spiking Neural Networks Open
This paper investigates the performance of deep convolutional spiking neural networks (DCSNNs) trained using spike-based backpropagation techniques. Specifically, the study examined temporal spike sequence learning via backpropagation (TSS…
View article: Collaborative Writing in the Intelligence Community
Collaborative Writing in the Intelligence Community Open
With new and evolving technology and ever-increasing remote collaboration, intelligence reporting processes are at a crossroads. Key questions about how best to collaboratively produce reports to get the right information to the right deci…
View article: Smartphone- and Cloud-based Artificial Intelligence Quantitative Analysis System (SCAISY) for SARS-CoV-2-specific IgG Antibody Lateral Flow Assays
Smartphone- and Cloud-based Artificial Intelligence Quantitative Analysis System (SCAISY) for SARS-CoV-2-specific IgG Antibody Lateral Flow Assays Open
Smartphone-based point-of-care testing (POCT) is rapidly emerging as an alternative to traditional screening and laboratory testing, particularly in resource-limited settings. In this proof-of-concept study, we present a smartphone- and cl…
View article: Critical role of TLR activation in viral replication, persistence, and pathogenicity of Theiler’s virus
Critical role of TLR activation in viral replication, persistence, and pathogenicity of Theiler’s virus Open
Theiler’s murine encephalomyelitis virus (TMEV) establishes persistent viral infections in the central nervous system and induces chronic inflammatory demyelinating disease in susceptible mice. TMEV infects dendritic cells, macrophages, B …
View article: Supplementary Table and Figures from Myeloma-Secreted Galectin-1 Potently Interacts with CD304 on Monocytic Myeloid-Derived Suppressor Cells
Supplementary Table and Figures from Myeloma-Secreted Galectin-1 Potently Interacts with CD304 on Monocytic Myeloid-Derived Suppressor Cells Open
File includes Supplementary Table S1 and Supplementary Figures S1-S7
View article: Supplementary Table and Figures from Myeloma-Secreted Galectin-1 Potently Interacts with CD304 on Monocytic Myeloid-Derived Suppressor Cells
Supplementary Table and Figures from Myeloma-Secreted Galectin-1 Potently Interacts with CD304 on Monocytic Myeloid-Derived Suppressor Cells Open
File includes Supplementary Table S1 and Supplementary Figures S1-S7
View article: Data from Myeloma-Secreted Galectin-1 Potently Interacts with CD304 on Monocytic Myeloid-Derived Suppressor Cells
Data from Myeloma-Secreted Galectin-1 Potently Interacts with CD304 on Monocytic Myeloid-Derived Suppressor Cells Open
Progression of multiple myeloma is regulated by factors intrinsic to the clonal plasma cells (PC) and by the immune effector cells in the tumor microenvironment. In this study, we investigated the interaction between CD304 expression on my…
View article: Data from Myeloma-Secreted Galectin-1 Potently Interacts with CD304 on Monocytic Myeloid-Derived Suppressor Cells
Data from Myeloma-Secreted Galectin-1 Potently Interacts with CD304 on Monocytic Myeloid-Derived Suppressor Cells Open
Progression of multiple myeloma is regulated by factors intrinsic to the clonal plasma cells (PC) and by the immune effector cells in the tumor microenvironment. In this study, we investigated the interaction between CD304 expression on my…
Senescent cancer cell-derived nanovesicle as a personalized therapeutic cancer vaccine Open
The development of therapeutic cancer vaccines (TCVs) that provide clinical benefits is challenging mainly due to difficulties in identifying immunogenic tumor antigens and effectively inducing antitumor immunity. Furthermore, there is an …