David Higgins
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View article: Memberdayakan anak Berarti Melindungi mereka Sendiri
Memberdayakan anak Berarti Melindungi mereka Sendiri Open
View article: eQTLs identify regulatory networks and drivers of variation in the individual response to sepsis
eQTLs identify regulatory networks and drivers of variation in the individual response to sepsis Open
View article: Glioma monitoring and assessment: Utility of amide proton transfer MRI
Glioma monitoring and assessment: Utility of amide proton transfer MRI Open
Magnetic resonance imaging (MRI) plays a key role in the planning of glioma biopsy as well as postoperative monitoring for recurrence or progression. This review describes amide proton transfer (APT) MRI and its application to glioma imagi…
View article: 4D Flow Cardiac MR in Primary Mitral Regurgitation
4D Flow Cardiac MR in Primary Mitral Regurgitation Open
Background Four‐dimensional‐flow cardiac MR (4DF‐MR) offers advantages in primary mitral regurgitation. The relationship between 4DF‐MR‐derived mitral regurgitant volume (MR‐Rvol) and the post‐operative left ventricular (LV) reverse remode…
View article: 169 Two-dimensional and four-dimensional velocity imaging quantified mitral regurgitation is associated with left ventricular remodelling post mitral valve surgery
169 Two-dimensional and four-dimensional velocity imaging quantified mitral regurgitation is associated with left ventricular remodelling post mitral valve surgery Open
Introduction Accurate assessment of degenerative mitral regurgitation (MRegurg) by transthoracic echocardiography (TTE) can be challenging. Phase-contrast cardiovascular magnetic resonance (PCMR) imaging enables reliable quantitation of MR…
View article: GJ3470-d and GJ3470-e: Discovery of Co-Orbiting Exoplanets in a Horseshoe Exchange Orbit
GJ3470-d and GJ3470-e: Discovery of Co-Orbiting Exoplanets in a Horseshoe Exchange Orbit Open
We report the discovery of a pair of exoplanets co-orbiting the red dwarf star GJ3470. The larger planet, GJ3470-d, was observed in a 14.9617-days orbit and the smaller planet, GJ3470-e, in a 14.9467-days orbit. GJ3470-d is sub-Jupiter siz…
View article: Validation of artificial intelligence containing products across the regulated healthcare industries
Validation of artificial intelligence containing products across the regulated healthcare industries Open
Purpose: The introduction of artificial intelligence / machine learning (AI/ML) products to the regulated fields of pharmaceutical research and development (R&D) and drug manufacture, and medical devices (MD) and in-vitro diagnostics (IVD)…
View article: Cardiac reverse remodeling in primary mitral regurgitation: mitral valve replacement vs. mitral valve repair
Cardiac reverse remodeling in primary mitral regurgitation: mitral valve replacement vs. mitral valve repair Open
View article: 9 A comparison between three quantitative perfusion post processing methods
9 A comparison between three quantitative perfusion post processing methods Open
Several analysis methods for Quantitative Perfusion (QP) CMR have been proposed, some vendor-specific, others generic. Published literature shows differences in the Myocardial Blood Flow (MBF) between these methods. Current limitations in…
View article: Asteroid spin-states of a 4 Gyr collisional family
Asteroid spin-states of a 4 Gyr collisional family Open
Context. Families of asteroids generated by the collisional fragmentation of a common parent body have been identified using clustering methods of asteroids in their proper orbital element space. However, there is growing evidence that som…
View article: Rationale and clinical applications of 4D flow cardiovascular magnetic resonance in assessment of valvular heart disease: a comprehensive review
Rationale and clinical applications of 4D flow cardiovascular magnetic resonance in assessment of valvular heart disease: a comprehensive review Open
View article: Expansion of a localized population of the introduced Stratiotes aloides (Hydrocharitaceae) in Lough Derg, Ireland
Expansion of a localized population of the introduced Stratiotes aloides (Hydrocharitaceae) in Lough Derg, Ireland Open
An expansion of an introduced female clone of Stratiotes aloides L. (Water-soldier) was located in a delta region on the western side of Lough Derg, Co Galway (v.c.H15), Ireland in 2007. This population was followed over a thirteen-year pe…
View article: 15 Biventricular assessment and quantification of primary mitral regurgitation is feasible and reproducible during continous supine exercise cardiovascular magnetic resonance
15 Biventricular assessment and quantification of primary mitral regurgitation is feasible and reproducible during continous supine exercise cardiovascular magnetic resonance Open
Background Biventricular volume and great vessel flow assessment during continuous supine free-breathing exercise cardiovascular magnetic resonance (Ex-CMR) has recently been validated in healthy volunteers using Compressed SENSEx3 (CS3) s…
View article: Exercise cardiovascular magnetic resonance: feasibility and development of biventricular function and great vessel flow assessment, during continuous exercise accelerated by Compressed SENSE: preliminary results in healthy volunteers
Exercise cardiovascular magnetic resonance: feasibility and development of biventricular function and great vessel flow assessment, during continuous exercise accelerated by Compressed SENSE: preliminary results in healthy volunteers Open
View article: Feasibility and validation of trans-valvular flow derived by four-dimensional flow cardiovascular magnetic resonance imaging in pacemaker recipients
Feasibility and validation of trans-valvular flow derived by four-dimensional flow cardiovascular magnetic resonance imaging in pacemaker recipients Open
View article: Feasibility and reproducibility of a cardiovascular magnetic resonance free-breathing, multi-shot, navigated image acquisition technique for ventricular volume quantification during continuous exercise
Feasibility and reproducibility of a cardiovascular magnetic resonance free-breathing, multi-shot, navigated image acquisition technique for ventricular volume quantification during continuous exercise Open
Exercise CMR using a free-breathing, multi-shot, navigated cine imaging method allows simultaneous assessment of left and right ventricular volumes during continuous exercise. Intra- and inter-observer reproducibility were excellent…
View article: 109 Feasibility and potential clinical utility of biventricular function, aortic and pulmonary flow assessment using compressed sense during continuous exercise cardiovascular magnetic resonance (EX-CMR)
109 Feasibility and potential clinical utility of biventricular function, aortic and pulmonary flow assessment using compressed sense during continuous exercise cardiovascular magnetic resonance (EX-CMR) Open
Background Biventricular volume, aortic and pulmonary flow assessment by cardiovascular magnetic resonance (CMR) allows accurate direct quantification of aortic and pulmonary flow and indirect quantification of mitral and tricuspid regurgi…
View article: Additional file 3 of T1 mapping performance and measurement repeatability: results from the multi-national T1 mapping standardization phantom program (T1MES)
Additional file 3 of T1 mapping performance and measurement repeatability: results from the multi-national T1 mapping standardization phantom program (T1MES) Open
Additional file 3. Supplementary data file reporting all the center-, session- and sequence-specific T1 mapping contributions to the T1MES program.
View article: Reference range determination for imaging biomarkers: Myocardial T<sub>1</sub>
Reference range determination for imaging biomarkers: Myocardial T<sub>1</sub> Open
Background Imaging biomarkers, such as the T 1 relaxation time of the myocardium using MRI, can be valuable in cardiac medicine if they are properly validated. Consensus statements recommend that for myocardial T 1 , each investigator shou…
View article: Towards accurate and precise T 1 and extracellular volume mapping in the myocardium: a guide to current pitfalls and their solutions
Towards accurate and precise T 1 and extracellular volume mapping in the myocardium: a guide to current pitfalls and their solutions Open
View article: Comparison of fast acquisition strategies in whole‐heart four‐dimensional flow cardiac MR: Two‐center, 1.5 Tesla, phantom and in vivo validation study
Comparison of fast acquisition strategies in whole‐heart four‐dimensional flow cardiac MR: Two‐center, 1.5 Tesla, phantom and in vivo validation study Open
Purpose To validate three widely‐used acceleration methods in four‐dimensional (4D) flow cardiac MR; segmented 4D‐spoiled‐gradient‐echo (4D‐SPGR), 4D‐echo‐planar‐imaging (4D‐EPI), and 4D‐ k‐t Broad‐use Linear Acquisition Speed‐up Technique…
View article: 026 Dimensional flow cardiovascular magnetic resonance: two-centre, 1.5t, phantom and in-vivo validation study
026 Dimensional flow cardiovascular magnetic resonance: two-centre, 1.5t, phantom and in-vivo validation study Open
Background Validation of four-dimensional (4D) flow CMR accelerated acquisition methods is needed to make them more robust for clinical applications.1 Our aim was to compare three widely-used acceleration methods in 4D flow CMR: 4D segment…
View article: Mixed tenure housing developments: Salt and pepper versus silo design
Mixed tenure housing developments: Salt and pepper versus silo design Open
Purpose - In the context of housing, mixed tenure attempts to bring together social groups in urban neighbourhoods to create a vibrant dynamic sustainable community. This paper focuses on residential development design in the context of ho…
View article: Standardised postprocessing of native T2 in detection and discrimination of myocarditis - comparison with native T1 mapping
Standardised postprocessing of native T2 in detection and discrimination of myocarditis - comparison with native T1 mapping Open
View article: The effect of changes to MOLLI scheme on T1 mapping and extra cellular volume calculation in healthy volunteers with 3 tesla cardiovascular magnetic resonance imaging.
The effect of changes to MOLLI scheme on T1 mapping and extra cellular volume calculation in healthy volunteers with 3 tesla cardiovascular magnetic resonance imaging. Open
The 5b(3s)3b MOLLI scheme agreed best with reference T1, without statistical difference between the six schemes. The shorter breath-hold time of 5b(3s)3b scheme may be preferable in clinical studies and warrants further investigation.
View article: Patient adaptive maximal resolution magnetic resonance myocardial stress perfusion imaging
Patient adaptive maximal resolution magnetic resonance myocardial stress perfusion imaging Open
Purpose To demonstrate the feasibility of an automatic adaptive acquisition sequence. Magnetic resonance perfusion pulse sequences often leave potential acquisition time unused in patients with lower heart‐rates (HR) and smaller body size.…
View article: Selection of magnetization catalyzation and readout methods for modified Look–Locker inversion recovery: A T1 mapping primer
Selection of magnetization catalyzation and readout methods for modified Look–Locker inversion recovery: A T1 mapping primer Open
View article: T1 values by conservative septal postprocessing approach are superior in relating to the interstitial myocardial fibrosis: findings from patients with severe aortic stenosis
T1 values by conservative septal postprocessing approach are superior in relating to the interstitial myocardial fibrosis: findings from patients with severe aortic stenosis Open
Background Accumulation of diffuse interstitial myocardial fibrosis in severe aortic stenosis relates to left ventricular (LV) functional impairment and determines the postoperative outcome in these patients. T1 mapping has been proposed f…
View article: Native T1 myocardial tissue characterisation in patients with pulmonary hypertension: findings from International T1 Multicentre Study
Native T1 myocardial tissue characterisation in patients with pulmonary hypertension: findings from International T1 Multicentre Study Open
View article: Split dose versus single bolus gadolinium administration in ecv calculation at 3 tesla cmr
Split dose versus single bolus gadolinium administration in ecv calculation at 3 tesla cmr Open