David J. Easty
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View article: An observational study of dose dense chemotherapy with lipegfilgrastim support in early breast cancer
An observational study of dose dense chemotherapy with lipegfilgrastim support in early breast cancer Open
Purpose Breast cancer is one of the most prevalent malignant diseases in women. The development of dose dense chemotherapy regimens has improved clinical outcomes but has been associated with increased hematological toxicity. Currently the…
View article: New Roles for Vitamin D Superagonists: From COVID to Cancer
New Roles for Vitamin D Superagonists: From COVID to Cancer Open
Vitamin D is a potent steroid hormone that induces widespread changes in gene expression and controls key biological pathways. Here we review pathophysiology of vitamin D with particular reference to COVID-19 and pancreatic cancer. Utility…
View article: When RON MET TAM in Mesothelioma: All Druggable for One, and One Drug for All?
When RON MET TAM in Mesothelioma: All Druggable for One, and One Drug for All? Open
Malignant pleural mesothelioma (MPM) is an aggressive inflammatory cancer with a poor survival rate. Treatment options are limited at best and drug resistance is common. Thus, there is an urgent need to identify novel therapeutic targets i…