David Jackson
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View article: A deep-time landscape of plant <i>cis</i> -regulatory sequence evolution
A deep-time landscape of plant <i>cis</i> -regulatory sequence evolution Open
Developmental gene function is conserved over deep time, but cis -regulatory sequence conservation is rarely found. Rapid sequence turnover, paleopolyploidy, structural variation, and limited phylogenomic sampling have impeded conserved no…
View article: Non-catalytic and catalytic TREHALOSE-6-PHOSPHATE SYNTHASES interact with RAMOSA3 to control maize development.
Non-catalytic and catalytic TREHALOSE-6-PHOSPHATE SYNTHASES interact with RAMOSA3 to control maize development. Open
Trehalose-6-phosphate (Tre6P) is the intermediate in the two-step pathway of trehalose biosynthesis mediated by Tre6P-synthases (TPSs) and Tre6P-phosphatases (TPPs). Plants harbor small families of TPS and TPP genes, however most plant TPS…
View article: Haroldo de Campos’ Galactic Observatory in São Paulo
Haroldo de Campos’ Galactic Observatory in São Paulo Open
This essay offers a comprehensive overview of the work and legacy of Haroldo de Campos (1929-2003), one of Brazil’s most influential and multifaceted literary figures. As a poet, essayist, translator, and intellectual, he played a central …
View article: Overcoming extensive redundancy in the arabidopsis <i>TREHALOSE-6-PHOSPHATE PHOSPHATASE</i> gene family reveals connections to development and iron homeostasis
Overcoming extensive redundancy in the arabidopsis <i>TREHALOSE-6-PHOSPHATE PHOSPHATASE</i> gene family reveals connections to development and iron homeostasis Open
Arabidopsis encodes ten TREHALOSE-6-PHOSPHATE PHOSPHATASE ( TPP ) genes, homologous to maize RAMOSA3 (I), which controls shoot branching. To explore the roles of the arabidopsis TPPs , we analyzed their expression in shoot apices and found…
View article: <i>Medicago truncatula CORYNE</i> modulates inflorescence meristem branching, nutrient signaling, and arbuscular mycorrhizal symbiosis
<i>Medicago truncatula CORYNE</i> modulates inflorescence meristem branching, nutrient signaling, and arbuscular mycorrhizal symbiosis Open
The CLAVATA signaling pathway regulates plant development and plant-environment interactions. CLAVATA signaling consists of mobile, cell-type or environment-specific CLAVATA3/ESR-related (CLE) peptides, which are perceived by a receptor co…
View article: <i>KRN5b</i> regulates maize kernel row number through mediating phosphoinositol signalling
<i>KRN5b</i> regulates maize kernel row number through mediating phosphoinositol signalling Open
Summary Kernel row number (KRN) is a major yield related trait for maize ( Zea mays L.) and is also a major goal of breeders, as it can increase the number of kernels per plant. Thus, identifying new genetic factors involving in KRN format…
View article: Heterozygous <i>fasciated ear</i> mutations improve yield traits in inbred and hybrid maize lines
Heterozygous <i>fasciated ear</i> mutations improve yield traits in inbred and hybrid maize lines Open
Heterozygous mutations in two genes encoding key regulators of development improve kernel row number in inbred and hybrid maize, revealing their potential for yield improvement.
View article: Enhancing Cybersecurity Posture: A Framework for Anomaly Detection in Cloud Computing Environments
Enhancing Cybersecurity Posture: A Framework for Anomaly Detection in Cloud Computing Environments Open
The rapid adoption of cloud computing has transformed the way organizations manage and store their data. However, this shift has also increased vulnerabilities to cyber threats. Anomaly detection is a critical component of cybersecurity fr…
View article: The additive function of <i>YIGE2</i> and <i>YIGE1</i> in regulating maize ear length
The additive function of <i>YIGE2</i> and <i>YIGE1</i> in regulating maize ear length Open
SUMMARY Ear length (EL) is a key trait that greatly contributes to yield in maize. Although dozens of EL quantitative trait loci have been mapped, very few causal genes have been cloned, and the molecular mechanisms remain largely unknown.…
View article: Large-scale single-cell profiling of stem cells uncovers redundant regulators of shoot development and yield trait variation
Large-scale single-cell profiling of stem cells uncovers redundant regulators of shoot development and yield trait variation Open
SUMMARY Stem cells in plant shoots are a rare population of cells that produce leaves, fruits and seeds, vital sources for food and bioethanol. Uncovering regulators expressed in these stem cells will inform crop engineering to boost produ…
View article: MaizeCODE reveals bi-directionally expressed enhancers that harbor molecular signatures of maize domestication
MaizeCODE reveals bi-directionally expressed enhancers that harbor molecular signatures of maize domestication Open
Modern maize was domesticated from Teosinte parviglumis , with subsequent introgressions from Teosinte mexicana , yielding increased kernel row number, loss of the hard fruit case and dissociation from the cob upon maturity, as well as few…
View article: The maize <scp><i>PLASTID TERMINAL OXIDASE</i></scp> (<scp><i>PTOX</i></scp>) locus controls the carotenoid content of kernels
The maize <span><i>PLASTID TERMINAL OXIDASE</i></span> (<span><i>PTOX</i></span>) locus controls the carotenoid content of kernels Open
SUMMARY Carotenoids perform a broad range of important functions in humans; therefore, carotenoid biofortification of maize ( Zea mays L.), one of the most highly produced cereal crops worldwide, would have a global impact on human health.…
View article: Taylor Swift and Influence: Sorting out the Effects of Celebrity and Other Political Endorsement
Taylor Swift and Influence: Sorting out the Effects of Celebrity and Other Political Endorsement Open
In this article we examine the effect of Taylor Swift's hypothetical endorsement of a Public policy position. We examine this in the context of not just the expanding literature on the effects of celebrity endorsements, but also through th…
View article: Taylor Swift and Influence: Sorting out the Effects of Celebrity and Other Political Endorsement
Taylor Swift and Influence: Sorting out the Effects of Celebrity and Other Political Endorsement Open
In this article we examine the effect of Taylor Swift's hypothetical endorsement of a Public policy position. We examine this in the context of not just the expanding literature on the effects of celebrity endorsements, but also through th…
View article: Tackling redundancy: genetic mechanisms underlying paralog compensation in plants
Tackling redundancy: genetic mechanisms underlying paralog compensation in plants Open
Summary Gene duplication is a powerful source of biological innovation giving rise to paralogous genes that undergo diverse fates. Redundancy between paralogous genes is an intriguing outcome of duplicate gene evolution, and its maintenanc…
View article: Monitoring environmental microbiomes: Alignment of microbiology and computational biology competencies within a culturally integrated curriculum and research framework
Monitoring environmental microbiomes: Alignment of microbiology and computational biology competencies within a culturally integrated curriculum and research framework Open
We have developed a flexible undergraduate curriculum that leverages the place‐based research of environmental microbiomes to increase the number of Indigenous researchers in microbiology, data science and scientific computing. Monitoring …
View article: A spatial transcriptome map of developing maize ear
A spatial transcriptome map of developing maize ear Open
A comprehensive understanding of inflorescence development is crucial for crop genetic improvement, as inflorescence meristems give rise to reproductive organs and determine grain yield. However, dissecting inflorescence development at the…
View article: The maize<i>PLASTID TERMINAL OXIDASE</i>(<i>PTOX</i>) gene controls the carotenoid content of kernels
The maize<i>PLASTID TERMINAL OXIDASE</i>(<i>PTOX</i>) gene controls the carotenoid content of kernels Open
SUMMARY Carotenoids perform a broad range of important functions in humans; therefore, carotenoid biofortification of maize ( Zea mays L.), one of the most highly produced cereal crops worldwide, would have a global impact on human health.…
View article: Survival and Chemosensitivity in Advanced High Grade Serous Epithelial Ovarian Cancer Patients with and without a BRCA Germline Mutation: More Evidence for Shifting the Paradigm towards Complete Surgical Cytoreduction
Survival and Chemosensitivity in Advanced High Grade Serous Epithelial Ovarian Cancer Patients with and without a BRCA Germline Mutation: More Evidence for Shifting the Paradigm towards Complete Surgical Cytoreduction Open
Background and Objectives: Approximately 10–15% of high-grade serous ovarian cancer (HGSOC) cases are related to BRCA germline mutations. Better survival rates and increased chemosensitivity are reported in patients with a BRCA 1/2 germlin…