David L. Cookmeyer
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View article: Supplementary Data from NPM–ALK-Induced Reprogramming of Mature TCR-Stimulated T Cells Results in Dedifferentiation and Malignant Transformation
Supplementary Data from NPM–ALK-Induced Reprogramming of Mature TCR-Stimulated T Cells Results in Dedifferentiation and Malignant Transformation Open
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View article: Data from NPM–ALK-Induced Reprogramming of Mature TCR-Stimulated T Cells Results in Dedifferentiation and Malignant Transformation
Data from NPM–ALK-Induced Reprogramming of Mature TCR-Stimulated T Cells Results in Dedifferentiation and Malignant Transformation Open
Fusion genes including NPM–ALK can promote T-cell transformation, but the signals required to drive a healthy T cell to become malignant remain undefined. In this study, we introduce NPM–ALK into primary human T cells and demonstrate induc…
View article: Data from NPM–ALK-Induced Reprogramming of Mature TCR-Stimulated T Cells Results in Dedifferentiation and Malignant Transformation
Data from NPM–ALK-Induced Reprogramming of Mature TCR-Stimulated T Cells Results in Dedifferentiation and Malignant Transformation Open
Fusion genes including NPM–ALK can promote T-cell transformation, but the signals required to drive a healthy T cell to become malignant remain undefined. In this study, we introduce NPM–ALK into primary human T cells and demonstrate induc…
View article: Supplementary Data from NPM–ALK-Induced Reprogramming of Mature TCR-Stimulated T Cells Results in Dedifferentiation and Malignant Transformation
Supplementary Data from NPM–ALK-Induced Reprogramming of Mature TCR-Stimulated T Cells Results in Dedifferentiation and Malignant Transformation Open
Supplemental Figures and Tables
View article: Progressive immune dysfunction with advancing disease stage in renal cell carcinoma
Progressive immune dysfunction with advancing disease stage in renal cell carcinoma Open
View article: Tyrosine phosphorylation is critical for ACLY activity in lipid metabolism and cancer
Tyrosine phosphorylation is critical for ACLY activity in lipid metabolism and cancer Open
A fundamental requirement for growth of rapidly proliferating cells is metabolic adaptation to promote synthesis of biomass 1 . ATP citrate lyase (ACLY) is a critical enzyme responsible for synthesis of cytosolic acetyl-CoA, the key buildi…
View article: The effect of divalent cations on the thermostability of type II polyketide synthase acyl carrier proteins
The effect of divalent cations on the thermostability of type II polyketide synthase acyl carrier proteins Open
The successful engineering of biosynthetic pathways hinges on understanding the factors that influence acyl carrier protein (ACP) stability and function. The stability and structure of ACPs can be influenced by the presence of divalent cat…
View article: Uncovering protein–protein interactions through a team-based undergraduate biochemistry course
Uncovering protein–protein interactions through a team-based undergraduate biochemistry course Open
How can we provide fertile ground for students to simultaneously explore a breadth of foundational knowledge, develop cross-disciplinary problem-solving skills, gain resiliency, and learn to work as a member of a team? One way is to integr…