David Looke
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View article: Win Ratio Analyses of Piperacillin-Tazobactam Versus Meropenem for Ceftriaxone-Nonsusceptible <i>Escherichia coli</i> or <i>Klebsiella pneumoniae</i> Bloodstream Infections: Post Hoc Insights From the MERINO Trial
Win Ratio Analyses of Piperacillin-Tazobactam Versus Meropenem for Ceftriaxone-Nonsusceptible <i>Escherichia coli</i> or <i>Klebsiella pneumoniae</i> Bloodstream Infections: Post Hoc Insights From the MERINO Trial Open
Background Clinical trials of treatments for serious infections commonly use the primary endpoint of all-cause mortality. However, many trial participants survive their infection and this endpoint may not truly reflect important benefits a…
View article: Australian state influenza notifications and school holiday closures in 2019
Australian state influenza notifications and school holiday closures in 2019 Open
Background: The impact of school holidays on influenza rates has been sparsely documented in Australia. In 2019, the early winter influenza season coincided with mid-year school breaks, enabling us the unusual opportunity to examine how in…
View article: Primary aortoduodenal fistula and chronic Q fever infection
Primary aortoduodenal fistula and chronic Q fever infection Open
We report a case of chronic Q fever presenting with catastrophic bleeding from an infected abdominal aortic aneurysm causing a primary aortoduodenal fistula in an 80-year-old retired farmer. This presentation is rarely reported in literatu…
View article: Australian state influenza notifications and school holiday closures in 2019
Australian state influenza notifications and school holiday closures in 2019 Open
Background: The impact of school holidays on influenza rates has been sparsely documented in Australia. In 2019, the early winter influenza season coincided with mid-year school breaks, enabling us the unusual opportunity to examine how in…
View article: Does copper treatment of commonly touched surfaces reduce healthcare-acquired infections? A systematic review and meta-analysis
Does copper treatment of commonly touched surfaces reduce healthcare-acquired infections? A systematic review and meta-analysis Open
View article: Fatal Respiratory Diphtheria Caused by ß-Lactam–Resistant <i>Corynebacterium diphtheriae</i>
Fatal Respiratory Diphtheria Caused by ß-Lactam–Resistant <i>Corynebacterium diphtheriae</i> Open
Background Diphtheria is a potentially fatal respiratory disease caused by toxigenic Corynebacterium diphtheriae. Although resistance to erythromycin has been recognized, β-lactam resistance in toxigenic diphtheria has not been described. …
View article: Does Copper treating of commonly touched surfaces reduce healthcare acquired infections? A Systematic Review and meta-analysis
Does Copper treating of commonly touched surfaces reduce healthcare acquired infections? A Systematic Review and meta-analysis Open
Background Healthcare acquired infections (HAIs) cause substantial morbidity and mortality. Copper appears to have strong viricidal properties under laboratory conditions. Aim We conducted a systematic review to examine the potential effec…
View article: Australian state influenza notifications and school closures in 2019
Australian state influenza notifications and school closures in 2019 Open
Background: The impact of school holidays on influenza rates has been sparsely documented in Australia. In 2019, the early winter influenza season coincided with mid-year school breaks, enabling us the unusual opportunity to examine how in…
View article: Modified measles with an atypical presentation
Modified measles with an atypical presentation Open
We report symptomatic confirmed modified measles infection in a person with one documented MMR (measles, mumps, rubella) vaccination and travel to Indonesia. No secondary cases were identified, consistent with other case reports of modifie…
View article: Effect of Piperacillin-Tazobactam vs Meropenem on 30-Day Mortality for Patients With <i>E coli</i> or <i>Klebsiella pneumoniae</i> Bloodstream Infection and Ceftriaxone Resistance
Effect of Piperacillin-Tazobactam vs Meropenem on 30-Day Mortality for Patients With <i>E coli</i> or <i>Klebsiella pneumoniae</i> Bloodstream Infection and Ceftriaxone Resistance Open
anzctr.org.au Identifiers: ACTRN12613000532707 and ACTRN12615000403538 and ClinicalTrials.gov Identifier: NCT02176122.
View article: Dominance of ST131<i>Escherichia coli</i>carrying<i>bla</i><sub>CTX-M</sub>in patients with bloodstream infections caused by cephalosporin-resistant strains in Australia, New Zealand and Singapore: whole genome analysis of isolates from a randomised trial
Dominance of ST131<i>Escherichia coli</i>carrying<i>bla</i><sub>CTX-M</sub>in patients with bloodstream infections caused by cephalosporin-resistant strains in Australia, New Zealand and Singapore: whole genome analysis of isolates from a randomised trial Open
Synopsis/Abstract Objectives To characterise multi-drug resistant Escherichia coli isolated from patients in Australia, New Zealand and Singapore with bloodstream infection (BSI). Methods We prospectively collected third-generation cephalo…
View article: The global challenges of infectious diseases
The global challenges of infectious diseases Open
Antimicrobial resistance, infection control, outbreak containment, vaccine development and diagnostic advances: adapting to a changing world In 2012, on behalf of the Australasian Society for Infectious Diseases (ASID), we reported in the …
View article: Risk factors for urinary catheter associated bloodstream infection
Risk factors for urinary catheter associated bloodstream infection Open