David Mann
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View article: Associations between remote patient monitoring and uncontrolled blood pressure among patients diagnosed with hypertension: Exploring variations by race/ethnicity
Associations between remote patient monitoring and uncontrolled blood pressure among patients diagnosed with hypertension: Exploring variations by race/ethnicity Open
Background Hypertension (HTN) is a critical public health concern that disproportionately impacts racial/ethnic minorities. The recent COVID-19 pandemic spurred rapid adoption of virtual HTN treatment programs such as remote patient monito…
View article: Evaluating Cognitive Load in Clinical Workflows Highlights Leverage Points for Guideline-Concordant Statin Initiation
Evaluating Cognitive Load in Clinical Workflows Highlights Leverage Points for Guideline-Concordant Statin Initiation Open
Introduction Linking EHR use to care quality offers insights for interventions to improve guideline adherence and close care gaps. We examine how EHR metadata can measure cognitive load in primary care providers during statin prescribing a…
View article: Utilization of Generative AI-drafted Responses for Managing Patient-Provider Communication
Utilization of Generative AI-drafted Responses for Managing Patient-Provider Communication Open
The integration of generative AI (GenAI) in patient communication presents benefits and challenges. This retrospective observational study analyzed EHR audit logs to assess how 75 healthcare professionals (HCPs) utilized AI-generated draft…
View article: When Nudges Don’t Budge: A Mixed Methods Study of Why EHR-Based Deprescribing Nudges Failed to Change Provider Behavior
When Nudges Don’t Budge: A Mixed Methods Study of Why EHR-Based Deprescribing Nudges Failed to Change Provider Behavior Open
View article: Bridging Technology and Pretest Genetic Services: Quantitative Study of Chatbot Interaction Patterns, User Characteristics, and Genetic Testing Decisions
Bridging Technology and Pretest Genetic Services: Quantitative Study of Chatbot Interaction Patterns, User Characteristics, and Genetic Testing Decisions Open
Background Among the alternative solutions being tested to improve access to genetic services, chatbots (or conversational agents) are being increasingly used for service delivery. Despite the growing number of studies on the accessibility…
View article: Nursing Performance Using Clinical Prediction Rules for Acute Respiratory Infection Management: A Case-Based Simulation
Nursing Performance Using Clinical Prediction Rules for Acute Respiratory Infection Management: A Case-Based Simulation Open
Overuse and misuse of antibiotics is an urgent health care problem and one of the key factors in antibiotic resistance. Validated clinical prediction rules have shown effectiveness in guiding providers to an appropriate diagnosis and ident…
View article: Barriers and Enablers for Sustaining Nurse-Led Use of Clinical Decision Support Tools for Antibiotic Stewardship: A qualitative analysis (Preprint)
Barriers and Enablers for Sustaining Nurse-Led Use of Clinical Decision Support Tools for Antibiotic Stewardship: A qualitative analysis (Preprint) Open
BACKGROUND Clinical decision support (CDS) tools embedded in electronic health records (EHRs) in the form of integrated clinical prediction rules (iCPRs) provide a potentially effective intervention to reduce inappropriate antibiotic pres…
View article: Utilization of Generative AI-drafted Responses for Managing Patient-Provider Communication
Utilization of Generative AI-drafted Responses for Managing Patient-Provider Communication Open
The integration of generative AI (GenAI) in patient communication presents benefits and challenges. This retrospective observational study analyzed EHR audit logs to assess how 75 healthcare professionals (HCPs) utilized AI generated draft…
View article: Importance of Prior Patient Interactions With the Healthcare System to Engaging With Pretest Cancer Genetic Services via Digital Health Tools Among Unaffected Primary Care Patients: Findings From the <scp>BRIDGE</scp> Trial
Importance of Prior Patient Interactions With the Healthcare System to Engaging With Pretest Cancer Genetic Services via Digital Health Tools Among Unaffected Primary Care Patients: Findings From the <span>BRIDGE</span> Trial Open
Objective To examine whether patient sociodemographic and clinical characteristics and prior interactions with the healthcare system were associated with opening patient portal messages related to cancer genetic services and beginning serv…
View article: A Qualitative Analysis of Remote Patient Monitoring: How a Paradox Mindset Can Support Balancing Emotional Tensions in the Design of Healthcare Technologies
A Qualitative Analysis of Remote Patient Monitoring: How a Paradox Mindset Can Support Balancing Emotional Tensions in the Design of Healthcare Technologies Open
Remote patient monitoring (RPM) is the use of digital technologies to improve patient care at a distance. However, current RPM solutions are often biased toward tech-savvy patients. To foster health equity, researchers have studied how to …
View article: Program Cost and Return on Investment of a Remote Patient Monitoring Program for Hypertension Management
Program Cost and Return on Investment of a Remote Patient Monitoring Program for Hypertension Management Open
Objective To evaluate the program costs and financial sustainability of a remote patient monitoring for hypertension (RPM-HTN) program implemented in the cardiology practice of a large healthcare system. Study Design This economic evaluati…
View article: Laypeople’s Use of and Attitudes Toward Large Language Models and Search Engines for Health Queries: Survey Study
Laypeople’s Use of and Attitudes Toward Large Language Models and Search Engines for Health Queries: Survey Study Open
Background Laypeople have easy access to health information through large language models (LLMs), such as ChatGPT, and search engines, such as Google. Search engines transformed health information access, and LLMs offer a new avenue for an…
View article: The MyLungHealth study protocol: a pragmatic patient-randomised controlled trial to evaluate a patient-centred, electronic health record-integrated intervention to enhance lung cancer screening in primary care
The MyLungHealth study protocol: a pragmatic patient-randomised controlled trial to evaluate a patient-centred, electronic health record-integrated intervention to enhance lung cancer screening in primary care Open
Introduction Early lung cancer screening (LCS) through low-dose CT (LDCT) is crucial but underused due to various barriers, including incomplete or inaccurate patient smoking data in the electronic health record and limited time for shared…
View article: A qualitative analysis of remote patient monitoring: how a paradox mindset can support balancing emotional tensions in the design of healthcare technologies
A qualitative analysis of remote patient monitoring: how a paradox mindset can support balancing emotional tensions in the design of healthcare technologies Open
Remote patient monitoring (RPM) is the use of digital technologies to improve patient care at a distance. However, current RPM solutions are often biased toward tech-savvy patients. To foster health equity, researchers have studied how to …
View article: Lightening the Load: Generative AI to Mitigate the Burden of the New Era of Obesity Medical Therapy
Lightening the Load: Generative AI to Mitigate the Burden of the New Era of Obesity Medical Therapy Open
Highly effective antiobesity and diabetes medications such as glucagon-like peptide 1 (GLP-1) agonists and glucose-dependent insulinotropic polypeptide/GLP-1 (dual) receptor agonists (RAs) have ushered in a new era of treatment of these hi…
View article: Snowball Group Usability Testing for Rapid and Iterative Multisite Tool Development: Method Development Study
Snowball Group Usability Testing for Rapid and Iterative Multisite Tool Development: Method Development Study Open
Background Usability testing is valuable for assessing a new tool or system’s usefulness and ease-of-use. Several established methods of usability testing exist, including think-aloud testing. Although usability testing has been shown to b…
View article: Metabolic resistance of Aβ3pE-42, a target epitope of the anti-Alzheimer therapeutic antibody, donanemab
Metabolic resistance of Aβ3pE-42, a target epitope of the anti-Alzheimer therapeutic antibody, donanemab Open
The amyloid β peptide (Aβ), starting with pyroglutamate (pE) at position 3 and ending at position 42 (Aβ3pE-42), predominantly accumulates in the brains of Alzheimer’s disease. Consistently, donanemab, a therapeutic antibody raised against…
View article: Uptake of Cancer Genetic Services for Chatbot vs Standard-of-Care Delivery Models
Uptake of Cancer Genetic Services for Chatbot vs Standard-of-Care Delivery Models Open
Importance Increasing numbers of unaffected individuals could benefit from genetic evaluation for inherited cancer susceptibility. Automated conversational agents (ie, chatbots) are being developed for cancer genetics contexts; however, ra…
View article: Bridging Gaps with Generative AI: Enhancing Hypertension Monitoring Through Patient and Provider Insights
Bridging Gaps with Generative AI: Enhancing Hypertension Monitoring Through Patient and Provider Insights Open
This study introduces a Generative Artificial Intelligence (GenAI) assistant designed to address key challenges in Remote Patient Monitoring (RPM) for hypertension. After a comprehensive needs assessment from clinicians and patients, we id…
View article: Large Language Model–Based Responses to Patients’ In-Basket Messages
Large Language Model–Based Responses to Patients’ In-Basket Messages Open
Importance Virtual patient-physician communications have increased since 2020 and negatively impacted primary care physician (PCP) well-being. Generative artificial intelligence (GenAI) drafts of patient messages could potentially reduce h…
View article: Laypeople’s Use of and Attitudes Toward Large Language Models and Search Engines for Health Queries: Survey Study (Preprint)
Laypeople’s Use of and Attitudes Toward Large Language Models and Search Engines for Health Queries: Survey Study (Preprint) Open
BACKGROUND Laypeople have easy access to health information through large language models (LLMs), such as ChatGPT, and search engines, such as Google. Search engines transformed health information access, and LLMs offer a new avenue for a…
View article: From silos to synergy: integrating academic health informatics with operational IT for healthcare transformation
From silos to synergy: integrating academic health informatics with operational IT for healthcare transformation Open
We have entered a new age of health informatics—applied health informatics—where digital health innovation cannot be pursued without considering operational needs. In this new digital health era, creating an integrated applied health infor…
View article: Effect of a behavioral nudge on adoption of an electronic health record-agnostic pulmonary embolism risk prediction tool: a pilot cluster nonrandomized controlled trial
Effect of a behavioral nudge on adoption of an electronic health record-agnostic pulmonary embolism risk prediction tool: a pilot cluster nonrandomized controlled trial Open
Objective Our objective was to determine the feasibility and preliminary efficacy of a behavioral nudge on adoption of a clinical decision support (CDS) tool. Materials and Methods We conducted a pilot cluster nonrandomized controlled tria…
View article: Ambulatory antibiotic prescription rates for acute respiratory infection rebound two years after the start of the COVID-19 pandemic
Ambulatory antibiotic prescription rates for acute respiratory infection rebound two years after the start of the COVID-19 pandemic Open
Background During the COVID-19 pandemic, acute respiratory infection (ARI) antibiotic prescribing in ambulatory care markedly decreased. It is unclear if antibiotic prescription rates will remain lowered. Methods We used trend analyses of …
View article: Navigating Remote Blood Pressure Monitoring—The Devil Is in the Details
Navigating Remote Blood Pressure Monitoring—The Devil Is in the Details Open
Shivan J. Mehta, MD, MBA, MSHP; Kevin G. Volpp, MD, PhD; Andrea B. Troxel, ScD; Joseph Teel, MD; Catherine R. Reitz, MPH; Alison Purcell, MSN, CRNP; Humphrey Shen, BA; Kiernan McNelis, BS; Christopher K. Snider, MPH; David A. Asch, MD, MBA
View article: Construction of the Digital Health Equity-Focused Implementation Research Conceptual Model - Bridging the Divide Between Equity-focused Digital Health and Implementation Research
Construction of the Digital Health Equity-Focused Implementation Research Conceptual Model - Bridging the Divide Between Equity-focused Digital Health and Implementation Research Open
Digital health implementations and investments continue to expand. As the reliance on digital health increases, it is imperative to implement technologies with inclusive and accessible approaches. A conceptual model can be used to guide eq…
View article: Mixed methods assessment of the influence of demographics on medical advice of ChatGPT
Mixed methods assessment of the influence of demographics on medical advice of ChatGPT Open
Objectives To evaluate demographic biases in diagnostic accuracy and health advice between generative artificial intelligence (AI) (ChatGPT GPT-4) and traditional symptom checkers like WebMD. Materials and Methods Combination symptom and d…
View article: Healthcare systems collaborating to implement a shared <scp>decision‐making</scp> tool in the electronic health record and build evidence on its adoption and use
Healthcare systems collaborating to implement a shared <span>decision‐making</span> tool in the electronic health record and build evidence on its adoption and use Open
Introduction Shared decision‐making (SDM) is a method of care by which patients and clinicians work together to co‐create a plan of care. Electronic health record (EHR) integration of SDM tools may increase adoption of SDM. We conducted a …
View article: Barriers to Implementing Registered Nurse–Driven Clinical Decision Support for Antibiotic Stewardship: Retrospective Case Study
Barriers to Implementing Registered Nurse–Driven Clinical Decision Support for Antibiotic Stewardship: Retrospective Case Study Open
Background Up to 50% of antibiotic prescriptions for upper respiratory infections (URIs) are inappropriate. Clinical decision support (CDS) systems to mitigate unnecessary antibiotic prescriptions have been implemented into electronic heal…
View article: Quantifying the impact of telemedicine and patient medical advice request messages on physicians' work-outside-work
Quantifying the impact of telemedicine and patient medical advice request messages on physicians' work-outside-work Open
The COVID-19 pandemic has boosted digital health utilization, raising concerns about increased physicians’ after-hours clinical work ("work-outside-work”). The surge in patients’ digital messages and additional time spent on work-outside-w…