David Minarik
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View article: Assessment of myocardial sympathetic innervation with [123I]mIBG myocardial scintigraphy: A comparative study between an Anger and a ring-configured cadmium-zinc-telluride gamma camera
Assessment of myocardial sympathetic innervation with [123I]mIBG myocardial scintigraphy: A comparative study between an Anger and a ring-configured cadmium-zinc-telluride gamma camera Open
Determining HMR from reprojected [123I]mIBG myocardial scintigraphy planar images acquired with a ring-configured CZT gamma camera is feasible and shows good agreement with HMR determined from planar images by a conventional Anger gamma ca…
View article: Evaluation of [18F]PSMA‐1007 uptake variability in patients with prostate cancer
Evaluation of [18F]PSMA‐1007 uptake variability in patients with prostate cancer Open
Background The biodistribution of PSMA‐ligands is of interest in radionuclide therapy planning. We investigated the variability of [ 18 F]PSMA‐1007 uptake in organs at risk and in relation to tumour burden in prostate cancer patients. Meth…
View article: AI based automatic measurement of split renal function in [18F]PSMA-1007 PET/CT
AI based automatic measurement of split renal function in [18F]PSMA-1007 PET/CT Open
Background Prostate-specific membrane antigen (PSMA) is an important target for positron emission tomography (PET) with computed tomography (CT) in prostate cancer. In addition to overexpression in prostate cancer cells, PSMA is expressed …
View article: High concordance of PET‐CT treatment response evaluation according to PERCIST 1.0 when comparing images reconstructed with OSEM vs. BSREM
High concordance of PET‐CT treatment response evaluation according to PERCIST 1.0 when comparing images reconstructed with OSEM vs. BSREM Open
Background Positron emission tomography (PET) response criteria in solid tumours (PERCIST 1.0) is a systematic assessment of therapy response with fluorine 18 fluorodeoxyglucose ([ 18 F]FDG) PET. The ordered subset expectation maximization…
View article: Verification of reprojected planar images generated from a ring-configured cadmium zinc telluride gamma camera in scintigraphy for diagnosing transthyretin cardiac amyloidosis
Verification of reprojected planar images generated from a ring-configured cadmium zinc telluride gamma camera in scintigraphy for diagnosing transthyretin cardiac amyloidosis Open
Aims Non-invasive diagnosis of amyloid transthyretin (ATTR) cardiac amyloidosis using planar scintigraphy and single-photon emission computed tomography-computed tomography (SPECT-CT) with [99mTc]Tc-3,3-diphosphono-1,2-propanodicarboxylic …
View article: First clinical experience of a ring‐configured cadmium zinc telluride camera: A comparative study versus conventional gamma camera systems
First clinical experience of a ring‐configured cadmium zinc telluride camera: A comparative study versus conventional gamma camera systems Open
Background A novel semiconductor cadmium zinc telluride (CZT) gamma camera system using a block sequential regularized expectation maximization (BSREM) reconstruction algorithm is now clinically available. Here we investigate how a multi‐p…
View article: AI-based quantification of whole-body tumour burden on somatostatin receptor PET/CT
AI-based quantification of whole-body tumour burden on somatostatin receptor PET/CT Open
Background Segmenting the whole-body somatostatin receptor-expressing tumour volume (SRETVwb) on positron emission tomography/computed tomography (PET/CT) images is highly time-consuming but has shown value as an independent prognostic fac…
View article: Applications of Artificial Intelligence in PSMA PET/CT for Prostate Cancer Imaging
Applications of Artificial Intelligence in PSMA PET/CT for Prostate Cancer Imaging Open
Prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) has emerged as an important imaging technique for prostate cancer. The use of PSMA PET/CT is rapidly increasing, while the number of nuclea…
View article: PET/CT imaging 2 h after injection of [18F]PSMA-1007 can lead to higher staging of prostate cancer than imaging after 1 h
PET/CT imaging 2 h after injection of [18F]PSMA-1007 can lead to higher staging of prostate cancer than imaging after 1 h Open
Background [ 18 F]PSMA-1007 is a prostate specific membrane antigen (PSMA) ligand for positron emission tomography (PET) imaging of prostate cancer. Current guidelines recommend imaging 90–120 min after injection but strong data about opti…
View article: [<sup>18</sup>F]PSMA‐1007 renal uptake parameters: Reproducibility and relationship to estimated glomerular filtration rate
[<sup>18</sup>F]PSMA‐1007 renal uptake parameters: Reproducibility and relationship to estimated glomerular filtration rate Open
Background Scintigraphy with technetium‐99m‐labelled dimercaptosuccinic acid ([ 99m Tc]Tc‐DMSA) is widely used for renal cortical imaging. Uptake of [ 99m Tc]Tc‐DMSA has been shown to correlate with glomerular filtration rate (GFR). Prosta…
View article: Biokinetics and dosimetry of <sup>18</sup>F‐PSMA‐1007 in patients with prostate cancer
Biokinetics and dosimetry of <sup>18</sup>F‐PSMA‐1007 in patients with prostate cancer Open
Purpose Positron emission tomography‐computed tomography (PET‐CT) using prostate‐specific membrane antigen (PSMA) ligands is a method for imaging prostate cancer. A recent tracer, 18 F‐PSMA‐1007, offers advantages concerning production and…
View article: Denoising of Scintillation Camera Images Using a Deep Convolutional Neural Network: A Monte Carlo Simulation Approach
Denoising of Scintillation Camera Images Using a Deep Convolutional Neural Network: A Monte Carlo Simulation Approach Open
Scintillation camera images contain a large amount of Poisson noise. We have investigated whether noise can be removed in whole-body bone scans using convolutional neural networks (CNNs) trained with sets of noisy and noiseless images obta…
View article: Reply: A Common Mistake in Assessing the Diagnostic Value of a Test: Failure to Account for Statistical and Methodologic Issues
Reply: A Common Mistake in Assessing the Diagnostic Value of a Test: Failure to Account for Statistical and Methodologic Issues Open
REPLY: Thank you for your interest and comments regarding our work ([1][1]). We agree that reproducibility/reliability and accuracy/validity are two different methodologic issues and should be evaluated using appropriate tests for each. Fu…
View article: A Preanalytic Validation Study of Automated Bone Scan Index: Effect on Accuracy and Reproducibility Due to the Procedural Variabilities in Bone Scan Image Acquisition
A Preanalytic Validation Study of Automated Bone Scan Index: Effect on Accuracy and Reproducibility Due to the Procedural Variabilities in Bone Scan Image Acquisition Open
In this study, we observed that the automated BSI accuracy and reproducibility were dependent on scanning speed but not on the vendor-specific γ-cameras. Prospective BSI studies should standardize scanning speed of bone scans to obtain ima…