David O. Irving
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View article: Differences in the product characteristics and clinical use of granulocytes for transfusion: The <scp>BEST</scp> Collaborative study
Differences in the product characteristics and clinical use of granulocytes for transfusion: The <span>BEST</span> Collaborative study Open
Background Whether granulocytes for transfusion are beneficial remains uncertain, although some evidence suggests that efficacy may be dose‐related. Granulocytes are mostly produced by apheresis procedure, but other means of production are…
View article: Frequent apheresis donation is not associated with adverse bone health in donors aged 45 years and over—Results from a cohort study in <scp>Australia</scp>
Frequent apheresis donation is not associated with adverse bone health in donors aged 45 years and over—Results from a cohort study in <span>Australia</span> Open
Background We investigated whether frequent apheresis donors have altered risk of bone fractures, and prescription of osteoporosis medicine//s due to their repeated exposure to citrate anticoagulant. Methods We used the Sax Institute's 45 …
View article: Seroprevalence of Japanese Encephalitis Virus and Other Flavivirus-Specific Antibodies Among Blood Donors in Australia Following a Novel Epidemic Spread of Japanese Encephalitis Virus
Seroprevalence of Japanese Encephalitis Virus and Other Flavivirus-Specific Antibodies Among Blood Donors in Australia Following a Novel Epidemic Spread of Japanese Encephalitis Virus Open
View article: Cross-sectional and longitudinal genotype to phenotype surveillance of SARS-CoV-2 variants over the first four years of the COVID-19 pandemic
Cross-sectional and longitudinal genotype to phenotype surveillance of SARS-CoV-2 variants over the first four years of the COVID-19 pandemic Open
View article: Genomic characterization of clinically significant blood group variants in Aboriginal Australians.
Genomic characterization of clinically significant blood group variants in Aboriginal Australians. Open
The comprehensive analyses of blood group genetic variant profiles identified in this study will provide insight and an opportunity to improve Aboriginal health by aiding in the identification of appropriate blood products for population-s…
View article: Regular whole blood donation and gastrointestinal, breast, colorectal and haematological cancer risk among blood donors in Australia
Regular whole blood donation and gastrointestinal, breast, colorectal and haematological cancer risk among blood donors in Australia Open
Background and Objectives Several studies have suggested that blood donors have lower risk of gastrointestinal and breast cancers, whereas some have indicated an increased risk of haematological cancers. We examined these associations by a…
View article: Has the frequency of <scp>ABO RhD</scp> blood groups in Australian blood donors changed as a result of the removal of the variant <scp>Creutzfeldt–Jakob</scp> disease‐based deferral?
Has the frequency of <span>ABO RhD</span> blood groups in Australian blood donors changed as a result of the removal of the variant <span>Creutzfeldt–Jakob</span> disease‐based deferral? Open
Background and Objectives Until 25 July 2022, Australians who had spent more than 6 months in the United Kingdom or territories between 1980 and 1996 were deferred from blood donation due to the risk of variant Creutzfeldt–Jakob disease. R…
View article: Seroprevalence of Japanese encephalitis virus-specific antibodies in Australia following novel epidemic spread: protocol for a national cross-sectional study
Seroprevalence of Japanese encephalitis virus-specific antibodies in Australia following novel epidemic spread: protocol for a national cross-sectional study Open
Introduction Japanese encephalitis virus (JEV) is a mosquito-borne flavivirus that causes encephalitis and other morbidity in Southeast Asia. Since February 2022, geographically dispersed JEV human, animal and vector detections occurred on…
View article: A preliminary study of entrepreneurial family businesses in New Zealand, and some implications for growth
A preliminary study of entrepreneurial family businesses in New Zealand, and some implications for growth Open
Family Business was rediscovered as a global phenomenon in the 1980s, about 10 years after researchers had rediscovered that, internationally, small and medium-sized businesses make a significant contribution to output, and to employment. …
View article: Cross-Sectional and Longitudinal Genotype to Phenotype Surveillance of SARS-CoV-2 Variants Over the First Four Years of the COVID-19 Pandemic
Cross-Sectional and Longitudinal Genotype to Phenotype Surveillance of SARS-CoV-2 Variants Over the First Four Years of the COVID-19 Pandemic Open
View article: The prevalence of selected clinically significant red blood cell antigens among Australian blood donors
The prevalence of selected clinically significant red blood cell antigens among Australian blood donors Open
View article: Serological testing of blood donors to characterise the impact of COVID-19 in Melbourne, Australia, 2020
Serological testing of blood donors to characterise the impact of COVID-19 in Melbourne, Australia, 2020 Open
Rapidly identifying and isolating people with acute SARS-CoV-2 infection has been a core strategy to contain COVID-19 in Australia, but a proportion of infections go undetected. We estimated SARS-CoV-2 specific antibody prevalence (seropre…
View article: Recovery of organ-specific tissue oxygen delivery at restrictive transfusion thresholds after fluid treatment in ovine haemorrhagic shock
Recovery of organ-specific tissue oxygen delivery at restrictive transfusion thresholds after fluid treatment in ovine haemorrhagic shock Open
Background Fluid resuscitation is the standard treatment to restore circulating blood volume and pressure after massive haemorrhage and shock. Packed red blood cells (PRBC) are transfused to restore haemoglobin levels. Restoration of micro…
View article: SEROLOGICAL TESTING OF BLOOD DONORS TO CHARACTERISE THE IMPACT OF COVID-19 IN MELBOURNE, AUSTRALIA, 2020
SEROLOGICAL TESTING OF BLOOD DONORS TO CHARACTERISE THE IMPACT OF COVID-19 IN MELBOURNE, AUSTRALIA, 2020 Open
Rapidly identifying and isolating people with acute SARS-CoV-2 infection has been a core strategy to contain COVID-19 in Australia, but a proportion of infections go undetected. We estimated SARS-CoV-2 specific antibody prevalence (seropre…
View article: The distribution of ABO RhD blood groups in Australia, based on blood donor and blood sample pathology data
The distribution of ABO RhD blood groups in Australia, based on blood donor and blood sample pathology data Open
Our national assessment of ABO RhD prevalence in Australia provides updated information for re-evaluating blood and blood product collection and holdings in light of changes in population demographic characteristics.
View article: Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus 2-Specific Antibodies in Australia After the First Epidemic Wave in 2020: A National Survey
Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus 2-Specific Antibodies in Australia After the First Epidemic Wave in 2020: A National Survey Open
Background As of mid-2021, Australia’s only nationwide coronavirus disease 2019 (COVID-19) epidemic occurred in the first 6 months of the pandemic. Subsequently, there has been limited transmission in most states and territories. Understan…
View article: RBCeq: A robust and scalable algorithm for accurate genetic blood typing
RBCeq: A robust and scalable algorithm for accurate genetic blood typing Open
This work was supported in part by Advance Queensland Research Fellowship, MRFF Genomics Health Futures Mission (76,757), and the Australian Red Cross LifeBlood. The Australian governments fund the Australian Red Cross Lifeblood for the pr…
View article: Serological testing of blood donors to characterise the impact of COVID-19 in Melbourne, 2020
Serological testing of blood donors to characterise the impact of COVID-19 in Melbourne, 2020 Open
Results of population-based age-stratified seroepidemiological investigation in Melbourne, Australia.
View article: Serological testing of blood donors to characterise the impact of COVID-19 in Melbourne, 2020
Serological testing of blood donors to characterise the impact of COVID-19 in Melbourne, 2020 Open
Results of population-based age-stratified seroepidemiological investigation in Melbourne, Australia.
View article: SARS-CoV-2 neutralizing antibodies: Longevity, breadth, and evasion by emerging viral variants
SARS-CoV-2 neutralizing antibodies: Longevity, breadth, and evasion by emerging viral variants Open
The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) antibody neutralization response and its evasion by emerging viral variants and variant of concern (VOC) are unknown, but critical to understand reinfection risk and breakthr…
View article: Development of CAR T-cell lymphoma in 2 of 10 patients effectively treated with<i>piggyBac</i>-modified CD19 CAR T cells
Development of CAR T-cell lymphoma in 2 of 10 patients effectively treated with<i>piggyBac</i>-modified CD19 CAR T cells Open
View article: Effect of Recombinant Human Perlecan Domain V Tethering Method on Protein Orientation and Blood Contacting Activity on Polyvinyl Chloride
Effect of Recombinant Human Perlecan Domain V Tethering Method on Protein Orientation and Blood Contacting Activity on Polyvinyl Chloride Open
Surface modification of biomaterials is a promising approach to control biofunctionality while retaining the bulk biomaterial properties. Perlecan is the major proteoglycan in the vascular basement membrane that supports low levels of plat…
View article: SARS Coronavirus-2 Microneutralisation and Commercial Serological Assays Correlated Closely for Some but Not All Enzyme Immunoassays
SARS Coronavirus-2 Microneutralisation and Commercial Serological Assays Correlated Closely for Some but Not All Enzyme Immunoassays Open
Serological testing for SARS-CoV-2-specific antibodies provides important research and diagnostic information relating to COVID-19 prevalence, incidence and host immune response. A greater understanding of the relationship between function…
View article: Seroprevalence of SARS‐CoV‐2‐specific antibodies in Sydney after the first epidemic wave of 2020
Seroprevalence of SARS‐CoV‐2‐specific antibodies in Sydney after the first epidemic wave of 2020 Open
Estimated SARS-CoV-2 seroprevalence was below 1%, indicating that community transmission was low during the first COVID-19 epidemic wave in Sydney. These findings suggest that early control of the spread of COVID-19 was successful, but eff…
View article: SARS-CoV-2 neutralizing antibodies; longevity, breadth, and evasion by emerging viral variants
SARS-CoV-2 neutralizing antibodies; longevity, breadth, and evasion by emerging viral variants Open
The SARS-CoV-2 antibody neutralization response and its evasion by emerging viral variants are unknown. Antibody immunoreactivity against SARS-CoV-2 antigens and Spike variants, inhibition of Spike-driven virus-cell fusion, and infectious …
View article: SARS Coronavirus-2 microneutralisation and commercial serological assays correlated closely for some but not all enzyme immunoassays
SARS Coronavirus-2 microneutralisation and commercial serological assays correlated closely for some but not all enzyme immunoassays Open
Background Serological testing for SARS-CoV-2 specific antibodies provides important research and diagnostic information relating to COVID-19 prevalence, incidence, and host immune response. A greater understanding of the relationship betw…
View article: Vox Sanguinis International Forum on Donor Incentives: Summary
Vox Sanguinis International Forum on Donor Incentives: Summary Open
View article: Vox Sanguinis International Forum on Donor Incentives
Vox Sanguinis International Forum on Donor Incentives Open
apheresis plasma units.
View article: Assessing the effect of risk factors on rates of obstetric transfusion over time using two methodological approaches
Assessing the effect of risk factors on rates of obstetric transfusion over time using two methodological approaches Open
View article: Outcomes of subsequent pregnancy following obstetric transfusion in a first birth
Outcomes of subsequent pregnancy following obstetric transfusion in a first birth Open
It is important to consider a woman's history of transfusion and/or haemorrhage as part of her obstetric history to ensure management in a manner that minimises risk in subsequent pregnancies.