David A. Peak
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View article: Post-traumatic stress and genetic interactions affect tobacco and alcohol use after trauma: findings from a multi-ancestry cohort
Post-traumatic stress and genetic interactions affect tobacco and alcohol use after trauma: findings from a multi-ancestry cohort Open
Tobacco smoking and drinking alcohol are common substance use behaviors influenced by both genetic risk and environmental exposures. Traumatic events are highly prevalent, affecting about 70% of people in their lifetime. After trauma, it i…
View article: Emotion Identification and Emotion Sensitivity Following Interpersonal and Noninterpersonal Traumatic Experiences: Results From the AURORA Study
Emotion Identification and Emotion Sensitivity Following Interpersonal and Noninterpersonal Traumatic Experiences: Results From the AURORA Study Open
Social cognition is an important mechanism linking trauma to psychopathology; however, current models fail to explain individual differences in social cognition after trauma exposure. We investigated whether the interpersonal nature of tra…
View article: This Article Corrects: “Persistent and Widespread Pain Among Blacks Six Weeks after MVC: Emergency Department-based Cohort Study”
This Article Corrects: “Persistent and Widespread Pain Among Blacks Six Weeks after MVC: Emergency Department-based Cohort Study” Open
Correction to: “Persistent and Widespread Pain Among Blacks Six Weeks after MVC: Emergency Department-based Cohort Study”
View article: Persistent and Widespread Pain Among Blacks Six Weeks after MVC: Emergency Department-based Cohort Study
Persistent and Widespread Pain Among Blacks Six Weeks after MVC: Emergency Department-based Cohort Study Open
INTRODUCTION: African-Americans in the United States experience greater persistent pain than non-Hispanic Whites across a range of medical conditions, but to our knowledge no longitudinal studies have examined the risk factors or incidence…
View article: Longitudinal Associations Between Peritraumatic Oestradiol and Fear Responding in Women and Men
Longitudinal Associations Between Peritraumatic Oestradiol and Fear Responding in Women and Men Open
PTSD is more prevalent in women than men and associated with autonomic dysfunction. Higher oestradiol levels have been associated with decreased PTSD severity, however, the impact of oestradiol on autonomic function is not well characteris…
View article: Childhood adversity is associated with longitudinal white matter changes after adulthood trauma
Childhood adversity is associated with longitudinal white matter changes after adulthood trauma Open
Background Childhood adversity is associated with susceptibility to posttraumatic stress disorder (PTSD) in adulthood. Both PTSD and adverse experiences in childhood are linked to disrupted white matter microstructure, yet the role of whit…
View article: Associations between residential segregation, ambient air pollution, and hippocampal features in recent trauma survivors
Associations between residential segregation, ambient air pollution, and hippocampal features in recent trauma survivors Open
Background Residential segregation is associated with differential exposure to air pollution. Hippocampus structure and function are highly susceptible to pollutants and associated with posttraumatic stress disorder (PTSD) development. The…
View article: Disentangling sex differences in PTSD risk factors: a systematic overview and multiple mediation analysis in the AURORA study
Disentangling sex differences in PTSD risk factors: a systematic overview and multiple mediation analysis in the AURORA study Open
Despite extensive of research on sex differences in posttraumatic stress disorder (PTSD), underlying mechanisms are still not fully understood. Here we present a systematic overview of three sex-related risk pathways. We assessed 16 risk f…
View article: Neighborhood Resources Associated With Psychological Trajectories and Neural Reactivity to Reward After Trauma
Neighborhood Resources Associated With Psychological Trajectories and Neural Reactivity to Reward After Trauma Open
Importance: Research on resilience after trauma has often focused on individual-level factors (eg, ability to cope with adversity) and overlooked influential neighborhood-level factors that may help mitigate the development of posttraumati…
View article: Peritraumatic C-reactive protein levels predict pain outcomes following traumatic stress exposure in a sex-dependent manner
Peritraumatic C-reactive protein levels predict pain outcomes following traumatic stress exposure in a sex-dependent manner Open
Background Chronic pain following traumatic stress exposure (TSE) is common. Increasing evidence suggests inflammatory/immune mechanisms are induced by TSE, play a key role in the recovery process versus development of post-TSE chronic pai…
View article: Social Buffering of Posttraumatic Stress Disorder: Longitudinal Effects and Neural Mediators
Social Buffering of Posttraumatic Stress Disorder: Longitudinal Effects and Neural Mediators Open
Our findings suggest that the neurocircuitry underlying the response to social threat cues is facilitated through broader pathways that involve the posterior hub of the default mode network.
View article: Understanding Onset, Dynamic Transitions, and Associated Inequality Risk Factors for Adverse Posttraumatic Neuropsychiatric Sequelae After Trauma Exposure
Understanding Onset, Dynamic Transitions, and Associated Inequality Risk Factors for Adverse Posttraumatic Neuropsychiatric Sequelae After Trauma Exposure Open
Several gaps remain in the understanding of the onset, dynamic transitions, and associated risk factors of adverse posttraumatic neuropsychiatric sequelae (APNS) in the acute post‐trauma window. Based on serial assessments of symptoms from…
View article: Understanding Onset, Dynamic Transitions, and Associated Inequality Risk Factors for Adverse Posttraumatic Neuropsychiatric Sequelae After Trauma Exposure
Understanding Onset, Dynamic Transitions, and Associated Inequality Risk Factors for Adverse Posttraumatic Neuropsychiatric Sequelae After Trauma Exposure Open
The findings can inform early intervention strategies for APNS, potentially reducing health disparities among trauma survivors.
View article: Early life adversity increases risk for chronic posttraumatic pain, data from humans and rodents
Early life adversity increases risk for chronic posttraumatic pain, data from humans and rodents Open
Traumatic stress exposures (TSE) are common in life. While most individuals recover following a TSE, a substantial subset develop adverse posttraumatic neuropsychiatric sequelae such as chronic posttraumatic musculoskeletal pain (CPMP). Vu…
View article: The reciprocal relationship between posttraumatic stress disorder symptoms and alcohol use in a large multisite longitudinal sample stratified by sex: A random-intercept cross-lagged panel model
The reciprocal relationship between posttraumatic stress disorder symptoms and alcohol use in a large multisite longitudinal sample stratified by sex: A random-intercept cross-lagged panel model Open
Background and aims: Posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD) often co-occur. There are a lack of longitudinal studies measuring the naturalistic development of PTSD and alcohol use problems in individuals with r…
View article: Neighborhood Resources Associated With Psychological Trajectories and Neural Reactivity to Reward After Trauma
Neighborhood Resources Associated With Psychological Trajectories and Neural Reactivity to Reward After Trauma Open
Importance Research on resilience after trauma has often focused on individual-level factors (eg, ability to cope with adversity) and overlooked influential neighborhood-level factors that may help mitigate the development of posttraumatic…
View article: Stress-related psychological symptoms contribute to axial pain persistence after motor vehicle collision
Stress-related psychological symptoms contribute to axial pain persistence after motor vehicle collision Open
Posttraumatic stress disorder (PTSD) symptoms and pain after traumatic events such as motor vehicle collision (MVC) have been proposed to be mutually promoting. We performed a prospective multicenter study that enrolled 948 individuals who…
View article: Neighborhood Disadvantage and Neural Correlates of Threat and Reward Processing in Survivors of Recent Trauma
Neighborhood Disadvantage and Neural Correlates of Threat and Reward Processing in Survivors of Recent Trauma Open
Importance Differences in neighborhood socioeconomic characteristics are important considerations in understanding differences in risk vs resilience in mental health. Neighborhood disadvantage is associated with alterations in the function…