David Prytherch
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View article: Improving predictive performance of Early Warning Scores by including trends in observations
Improving predictive performance of Early Warning Scores by including trends in observations Open
The results of this study confirm that, not only can the performance of models predicting clinical deterioration be increased by including trends, but that a logistic regression-based model with very few predictors can predict the risk of …
View article: Age does not improve the predictive ability of the Hospital Frailty Risk Score for length of stay
Age does not improve the predictive ability of the Hospital Frailty Risk Score for length of stay Open
Background The Hospital Frailty Risk Score (HFRS) has been widely used to identify patients at high risk of poor outcomes and to predict poor outcomes for older people. Although poor health outcomes are associated more with frailty than ag…
View article: Comparison of Early Warning Scores Utilising Patient Trends
Comparison of Early Warning Scores Utilising Patient Trends Open
Early Warning Scores are support tools intended to help clinicians recognise and intervene with in-hospital patient deterioration early on and thus prevent adverse patient outcomes (e.g. death). State-of-the-art early warning scores in use…
View article: Using the Hospital Frailty Risk Score to Predict In-Hospital Mortality Across All Ages
Using the Hospital Frailty Risk Score to Predict In-Hospital Mortality Across All Ages Open
This study investigates the relationship between the Hospital Frailty Risk Score (HFRS) and in-hospital mortality in adult patients. A retrospective cohort analysis of patients aged 16 and older admitted to Queen Alexandra Hospital, Portsm…
View article: Using the Hospital Frailty Risk Score to predict length of stay across all adult ages
Using the Hospital Frailty Risk Score to predict length of stay across all adult ages Open
Background Hospital Frailty Risk Score (HFRS) has recently been used to predict adverse health outcomes including length of stay (LOS) in hospital. LOS is an important indicator for patient quality of care, the measurement of hospital perf…
View article: Safer and more efficient vital signs monitoring protocols to identify the deteriorating patients in the general hospital ward: an observational study
Safer and more efficient vital signs monitoring protocols to identify the deteriorating patients in the general hospital ward: an observational study Open
Background The frequency at which patients should have their vital signs (e.g. blood pressure, pulse, oxygen saturation) measured on hospital wards is currently unknown. Current National Health Service monitoring protocols are based on exp…
View article: Operative and non-operative management for intestinal emergencies: findings from a single-centre retrospective cohort study
Operative and non-operative management for intestinal emergencies: findings from a single-centre retrospective cohort study Open
Background Patients with an intestinal emergency who do not have surgery are poorly characterised. This study used electronic healthcare records to provide a rapid insight into the number of patients admitted with an intestinal emergency a…
View article: Evaluating the performance of the National Early Warning Score in different diagnostic groups
Evaluating the performance of the National Early Warning Score in different diagnostic groups Open
Consistently high performance indicates that NEWS is a suitable early warning score to use for all diagnostic groups considered by this analysis, and patients are not disadvantaged through use of NEWS in comparison to any of the other eval…
View article: Issue Information – Editorial Board
Issue Information – Editorial Board Open
View article: Combining viral genomics and clinical data to assess risk factors for severe COVID-19 (mortality, ICU admission, or intubation) amongst hospital patients in a large acute UK NHS hospital Trust
Combining viral genomics and clinical data to assess risk factors for severe COVID-19 (mortality, ICU admission, or intubation) amongst hospital patients in a large acute UK NHS hospital Trust Open
Throughout the COVID-19 pandemic, valuable datasets have been collected on the effects of the virus SARS-CoV-2. In this study, we combined whole genome sequencing data with clinical data (including clinical outcomes, demographics, comorbid…
View article: SP10.1.2 Novel Predictors of Mortality in Emergency Bowel Surgery: A Single Centre Cohort Study
SP10.1.2 Novel Predictors of Mortality in Emergency Bowel Surgery: A Single Centre Cohort Study Open
Aims Pre-operative risk stratification is a key part of the care pathway for emergency bowel surgery, as it facilitates the identification of high-risk patients. A limitation of current risk models is that they utilise operative data in th…
View article: NELA.03Laparoscopy in Emergency Surgery is Associated with Lower Risk-Adjusted Mortality
NELA.03Laparoscopy in Emergency Surgery is Associated with Lower Risk-Adjusted Mortality Open
Aims To compare risk-adjusted outcomes after emergency intestinal surgery by operative approach. Methods Data from December 2013-November 2018 was retrieved from the NELA national database. Complete data on 102,154 patients with P-POSSUM w…
View article: Reply to: Performance of the National Early Warning Score in hospitalised patients infected by Covid-19
Reply to: Performance of the National Early Warning Score in hospitalised patients infected by Covid-19 Open
View article: S97 The performance of the national early warning score and national early warning score 2 in hospitalised patients infected by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
S97 The performance of the national early warning score and national early warning score 2 in hospitalised patients infected by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Open
Introduction The National Early Warning Score (NEWS) and its update, NEWS2, are validated scoring systems for identifying patient deterioration in a range of clinical conditions, including infection and sepsis. Coronavirus disease 2019 (CO…
View article: Detecting deteriorating patients in hospital: development and validation of a novel scoring system
Detecting deteriorating patients in hospital: development and validation of a novel scoring system Open
Rationale: Late recognition of patient deterioration in hospital is associated with worse outcomes, including higher mortality. Despite the widespread introduction of early warning score systems and electronic health recor…
View article: Impact of the coronavirus pandemic on the patterns of vital signs recording and staff compliance with expected monitoring schedules on general wards
Impact of the coronavirus pandemic on the patterns of vital signs recording and staff compliance with expected monitoring schedules on general wards Open
View article: The performance of the National Early Warning Score and National Early Warning Score 2 in hospitalised patients infected by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
The performance of the National Early Warning Score and National Early Warning Score 2 in hospitalised patients infected by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Open
View article: Early warning score adjusted for age to predict the composite outcome of mortality, cardiac arrest or unplanned intensive care unit admission using observational vital-sign data: a multicentre development and validation
Early warning score adjusted for age to predict the composite outcome of mortality, cardiac arrest or unplanned intensive care unit admission using observational vital-sign data: a multicentre development and validation Open
Objectives Early warning scores (EWS) alerting for in-hospital deterioration are commonly developed using routinely collected vital-sign data from the whole in-hospital population. As these in-hospital populations are dominated by those ov…
View article: The National Early Warning Score 2 (NEWS2)
The National Early Warning Score 2 (NEWS2) Open
Editor – Hodgson et al [1][1] demonstrate that the recent modification of the National Early Warning Score (NEWS) – NEWS2 – prove less sensitive than NEWS in identifying in-hospital death for patients with acute exacerbations of chronic ob…
View article: The effect of fractional inspired oxygen concentration on early warning score performance: A database analysis
The effect of fractional inspired oxygen concentration on early warning score performance: A database analysis Open
View article: Reply to: NEWS2 needs to be tested in prospective trials involving patients with confirmed hypercapnia
Reply to: NEWS2 needs to be tested in prospective trials involving patients with confirmed hypercapnia Open
View article: Sepsis in Non-ICU Patients: A Call for Guideline Reassessment - The authors reply.
Sepsis in Non-ICU Patients: A Call for Guideline Reassessment - The authors reply. Open
View article: Nurse staffing levels, missed vital signs and mortality in hospitals: retrospective longitudinal observational study
Nurse staffing levels, missed vital signs and mortality in hospitals: retrospective longitudinal observational study Open
Background Low nurse staffing levels are associated with adverse patient outcomes from hospital care, but the causal relationship is unclear. Limited capacity to observe patients has been hypothesised as a causal mechanism. Objectives This…
View article: A comparison of the ability of the National Early Warning Score and the National Early Warning Score 2 to identify patients at risk of in-hospital mortality: A multi-centre database study
A comparison of the ability of the National Early Warning Score and the National Early Warning Score 2 to identify patients at risk of in-hospital mortality: A multi-centre database study Open
View article: Predicting in-hospital mortality and unanticipated admissions to the intensive care unit using routinely collected blood tests and vital signs: Development and validation of a multivariable model
Predicting in-hospital mortality and unanticipated admissions to the intensive care unit using routinely collected blood tests and vital signs: Development and validation of a multivariable model Open
View article: A Comparison of the Quick Sequential (Sepsis-Related) Organ Failure Assessment Score and the National Early Warning Score in Non-ICU Patients With/Without Infection
A Comparison of the Quick Sequential (Sepsis-Related) Organ Failure Assessment Score and the National Early Warning Score in Non-ICU Patients With/Without Infection Open
Objectives: The Sepsis-3 task force recommended the quick Sequential (Sepsis-Related) Organ Failure Assessment score for identifying patients with suspected infection who are at greater risk of poor outcomes, but many hospitals already use…
View article: External validation of the National Early Warning Score 2 (NEWS2) prediction of in-hospital death in patients with type II respiratory failure: a multi-centre database study [protocol]
External validation of the National Early Warning Score 2 (NEWS2) prediction of in-hospital death in patients with type II respiratory failure: a multi-centre database study [protocol] Open
Background: The National Early Warning Score (NEWS), a vital-signs-based early warning score (EWS), has been suggested to perform poorly in patients with hypercapnic respiratory failure. A newly updated version (NEWS2) includes modi…
View article: National Early Warning Score Accurately Discriminates the Risk of Serious Adverse Events in Patients With Liver Disease
National Early Warning Score Accurately Discriminates the Risk of Serious Adverse Events in Patients With Liver Disease Open
View article: What impact does nursing care left undone have on patient outcomes? Review of the literature
What impact does nursing care left undone have on patient outcomes? Review of the literature Open
Aims and objectives Systematic review of the impact of missed nursing care on outcomes in adults, on acute hospital wards and in nursing homes. Background A considerable body of evidence supports the hypothesis that lower levels of registe…
View article: Response to Inpatient illness severity surveys provide essential data for planning capacity and managing patient flow in the acute hospital setting <i>(J Intensive Care Soc</i> 2016; 17: 196–201)
Response to Inpatient illness severity surveys provide essential data for planning capacity and managing patient flow in the acute hospital setting <i>(J Intensive Care Soc</i> 2016; 17: 196–201) Open