Explanipedia

SAT-331 Elucidating the Role of Breast Cancer Specific GATA3 Mutation in Estrogen Receptor Positive Breast Cancer Open

Kristopher A. Lofgren, Natasha Emmanuel, David R. Meier, Paraic A. Kenny · 2019

Approximately 266,000 women will be newly diagnosed with invasive breast cancer in the US this year, making it the most prevalent cancer in females, resulting in a 1 in 8 lifetime risk. Many of these tumors are of the hormone receptor posi…

Genomic case report of a low grade bladder tumor metastasis to lung Open

Marvin J. Van Every, Garrett M. Dancik, Venki Paramesh, Grzegorz T. Gurda, David R. Meier , et al. · 2018

Mutant GATA3 Actively Promotes the Growth of Normal and Malignant Mammary Cells Open

Natasha Emmanuel, Kristopher A. Lofgren, Esther A. Peterson, David R. Meier, Eric H. Jung , et al. · 2018

GATA3 mutations, recently observed in breast cancer, encode active transcription factors, which elicit proliferative phenotypes in normal mammary epithelium and promote the growth of ER-positive breast cancer cell lines.

Glycogen debranching enzyme (AGL) is a novel regulator of non-small cell lung cancer growth Open

Craig S. Richmond, Darby G. Oldenburg, Garrett M. Dancik, David R. Meier, Benjamin Weinhaus , et al. · 2018

Glycogen debranching enzyme (AGL) and Glycogen phosphorylase (PYG) are responsible for glycogen breakdown. We have earlier shown that AGL is a regulator of bladder tumor growth. Here we investigate the role of AGL in non-small cell lung ca…

Additional file 4: of Genomic case report of a low grade bladder tumor metastasis to lung Open