David S. Rampton
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View article: Understanding and managing psychological disorders in patients with inflammatory bowel disease: a practical guide
Understanding and managing psychological disorders in patients with inflammatory bowel disease: a practical guide Open
Mood disturbances such as anxiety and depression are common in patients with inflammatory bowel disease (IBD), and impact negatively on their quality of life and disease course. An integrated multidisciplinary IBD team, which includes acce…
View article: Use of <scp>intravenous</scp> iron and risk of anaphylaxis: A multinational observational <scp>post‐authorisation</scp> safety study in Europe
Use of <span>intravenous</span> iron and risk of anaphylaxis: A multinational observational <span>post‐authorisation</span> safety study in Europe Open
Purpose This post‐authorisation safety study estimated the risk of anaphylaxis in patients receiving intravenous (IV) iron in Europe, with interest in iron dextran and iron non‐dextrans. Studies conducted in the United States have reported…
View article: Association of Genetic Variants in <i>NUDT15</i> With Thiopurine-Induced Myelosuppression in Patients With Inflammatory Bowel Disease
Association of Genetic Variants in <i>NUDT15</i> With Thiopurine-Induced Myelosuppression in Patients With Inflammatory Bowel Disease Open
Among patients of European ancestry with IBD, variants in NUDT15 were associated with increased risk of TIM. These findings suggest that NUDT15 genotyping may be considered prior to initiation of thiopurine therapy; however, further study …
View article: Editorial: which iron preparation for patients with IBD?
Editorial: which iron preparation for patients with IBD? Open
Linked Content This article is linked to Aksan et al papers. To view these articles visit https://doi.org/10.1111/apt.14126 and https://doi.org/10.1111/apt.14043 .
View article: Oral Iron Treatment Response and Predictors in Anaemic Adolescents and Adults with IBD: A Prospective Controlled Open-Label Trial
Oral Iron Treatment Response and Predictors in Anaemic Adolescents and Adults with IBD: A Prospective Controlled Open-Label Trial Open
Oral ferrous sulphate was no less effective or well-tolerated in adolescents than adults, and did not increase disease activity in this short-term study. The inverse relation between baseline CRP and hepcidin levels and the haemoglobin res…
View article: Incidence and Outcome of <i>Clostridium difficile</i> Infection in Hospitalized Patients with Inflammatory Bowel Disease in the UK
Incidence and Outcome of <i>Clostridium difficile</i> Infection in Hospitalized Patients with Inflammatory Bowel Disease in the UK Open
The incidence of CDI complicating IBD has fallen since 2007. CDI is no longer associated with worse short-term outcomes in patients with IBD than in those without. Patients with CDI and IBD have similar outcomes to those with IBD alone.
View article: Hypersensitivity to intravenous iron: classification, terminology, mechanisms and management
Hypersensitivity to intravenous iron: classification, terminology, mechanisms and management Open
Intravenous (IV) iron therapy is widely used in iron deficiency anaemias when oral iron is not tolerated or ineffective. Administration of IV‐iron is considered a safe procedure, but severe hypersensitivity reactions (HSRs) can occur at a …
View article: On the safety of intravenous iron, evidence trumps conjecture
On the safety of intravenous iron, evidence trumps conjecture Open
Anemia is one of the world’s most common disorders. In 2010, global anemia prevalence was 32.9%, affecting over 2.2 billion people, and iron deficiency the most common of the causes.[1][1] Oral iron, while inexpensive and effective when ta…
View article: Treatment of iron deficiency anemia: practical considerations
Treatment of iron deficiency anemia: practical considerations Open
Iron deficiency anemia is a common problem worldwide, and doctors of all specialties need to be competent in its treatment. While most patients respond well to oral iron preparations, a substantial minority have side effects that make them…