David Ryoo
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View article: Probing the Dynamics of Yersinia Adhesin A (YadA) in Outer Membranes Hints at Requirements for β-Barrel Membrane Insertion
Probing the Dynamics of Yersinia Adhesin A (YadA) in Outer Membranes Hints at Requirements for β-Barrel Membrane Insertion Open
The vast majority of cells are protected and functionalized by a dense surface layer of glycans, proteoglycans, and glycolipids. This surface represents an underexplored space in structural biology that is exceedingly challenging to recrea…
View article: Thicket and Mesh: How the Outer Membrane Can Resist Tension Imposed by the Cell Wall
Thicket and Mesh: How the Outer Membrane Can Resist Tension Imposed by the Cell Wall Open
The cell envelope of Gram-negative bacteria is composed of an outer membrane (OM) and an inner membrane (IM) and a peptidoglycan cell wall (CW) between them. Combined with Braun's lipoprotein (Lpp), which connects the OM and the CW, and nu…
View article: Modelling intermediates of BamA folding an outer membrane protein
Modelling intermediates of BamA folding an outer membrane protein Open
These are the hybrid-barrel models built and simulated for BamA-EspP(n), BAM-EspP, and BAM-BamA intermediate states. Included files are the protein structure file (psf) and equilibrium simulation trajectory files (dcd); does not include wa…
View article: Modeling intermediates of BamA folding an outer membrane protein
Modeling intermediates of BamA folding an outer membrane protein Open
View article: The Role of Extracellular Loops in the Folding of Outer Membrane Protein X (OmpX) of Escherichia coli
The Role of Extracellular Loops in the Folding of Outer Membrane Protein X (OmpX) of Escherichia coli Open
The outer membrane of Gram-negative bacteria acts as an additional diffusion barrier for solutes and nutrients. It is perforated by outer membrane proteins (OMPs) that function most often as diffusion pores, but sometimes also as parts of …
View article: Author response: Adaptation of the periplasm to maintain spatial constraints essential for cell envelope processes and cell viability
Author response: Adaptation of the periplasm to maintain spatial constraints essential for cell envelope processes and cell viability Open
View article: Plasticity within the barrel domain of BamA mediates a hybrid-barrel mechanism by BAM
Plasticity within the barrel domain of BamA mediates a hybrid-barrel mechanism by BAM Open
View article: Inward-facing glycine residues create sharp turns in β-barrel membrane proteins
Inward-facing glycine residues create sharp turns in β-barrel membrane proteins Open
View article: BamB Stabilizes BamA's Laterally Open and Closed States
BamB Stabilizes BamA's Laterally Open and Closed States Open
View article: Periplasm homeostatic regulation maintains spatial constraints essential for cell envelope processes and cell viability
Periplasm homeostatic regulation maintains spatial constraints essential for cell envelope processes and cell viability Open
The cell envelope of Gram-negative bacteria consists of two membranes surrounding a periplasm and peptidoglycan layer. Molecular machines spanning the cell envelope depend on spatial constraints and load-bearing forces across the cell enve…
View article: BamA is required for autotransporter secretion
BamA is required for autotransporter secretion Open
View article: Quantitative Comparisons of Competing Models of Autotransporter Passenger-Domain Secretion
Quantitative Comparisons of Competing Models of Autotransporter Passenger-Domain Secretion Open
View article: Lateral Gate Opening of BAM Complex Studied by Free Energy Calculations and the String Method
Lateral Gate Opening of BAM Complex Studied by Free Energy Calculations and the String Method Open
View article: Probing Bama's Role in the Assembly of Trimeric Autotransporter Adhesins
Probing Bama's Role in the Assembly of Trimeric Autotransporter Adhesins Open