David S. Gardner
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View article: Machine learning prediction of moderate‐to‐severe acute kidney injury after <scp>ICU</scp> admission and cardiac surgery with urine trace elements
Machine learning prediction of moderate‐to‐severe acute kidney injury after <span>ICU</span> admission and cardiac surgery with urine trace elements Open
Background Acute kidney injury (AKI) is common and linked to poor outcomes, but early detection remains challenging. Previous research identified urinary trace elements (TE) as early AKI biomarkers in intensive care unit (ICU) or cardiac s…
View article: Environmental impact of feeding plant-based vs. meat-based dry dog foods in the United Kingdom
Environmental impact of feeding plant-based vs. meat-based dry dog foods in the United Kingdom Open
Introduction Pet food production contributes substantially to global environmental pressures, driven largely by animal-derived ingredients. The current study quantified the environmental impacts of 31 commercially available dry dog foods p…
View article: Lipid droplets in felid kidneys: prevalence and composition by lipidomics
Lipid droplets in felid kidneys: prevalence and composition by lipidomics Open
An accepted and common phenotypic curiosity of Felidae is the presence of intracytoplasmic lipid droplets in renal proximal tubule epithelial cells (RPTEC), also frequently in urine (lipuria). Both outcomes are currently considered, and ta…
View article: Nutritional analysis of commercially available, complete plant- and meat-based dry dog foods in the UK
Nutritional analysis of commercially available, complete plant- and meat-based dry dog foods in the UK Open
Background Adoption of a plant-based diet is a popular lifestyle choice for many owners of canine companion animals. Increasingly, owners would like to feed their canine companions a similar diet. A plant-based dietary pattern has been rep…
View article: A novel resistant starch supplement induced significant weight loss in obese/overweight dogs
A novel resistant starch supplement induced significant weight loss in obese/overweight dogs Open
Objectives To evaluate whether a resistant-starch containing supplement administered for 30 days would induce significant weight loss and lower body condition score (BCS) in overweight/obese dogs, compared to placebo. Methods 21 home-based…
View article: Environmental Impacts of Dry Vegan Dog Food: A Comprehensive UK Analysis
Environmental Impacts of Dry Vegan Dog Food: A Comprehensive UK Analysis Open
Introduction Pet food production contributes substantially to global environmental pressures, driven largely by animal-derived ingredients. The current study quantified the environmental impacts of 31 commercially available dry dog foods p…
View article: Prioritizing Mental Health in Sickle Cell Disease: Implementing Routine Psychological and Neurocognitive Assessments in a Comprehensive Sickle Cell Clinic
Prioritizing Mental Health in Sickle Cell Disease: Implementing Routine Psychological and Neurocognitive Assessments in a Comprehensive Sickle Cell Clinic Open
Introduction: Sickle cell disease (SCD) is an inherited hemoglobinopathy that can lead to significant physical and psychosocial challenges. Mental health concerns and neurocognitive deficits are highly prevalent but underrecognized in indi…
View article: Temporal Trends in Equine Sperm Motility and Semen Volume: A Retrospective Analysis from a Single UK Breeding Facility
Temporal Trends in Equine Sperm Motility and Semen Volume: A Retrospective Analysis from a Single UK Breeding Facility Open
The equine industry preferentially selects sires based on pedigree, performance, and conformation, with little concern given to fertility. Increasing evidence supports the theory of geographic-sensitive declines in a range of semen quality…
View article: Nutritional analysis of commercially available, complete plant- and meat-based dry dog foods in the UK
Nutritional analysis of commercially available, complete plant- and meat-based dry dog foods in the UK Open
Background Adoption of a plant-based diet is a popular lifestyle choice for many owners of canine companion animals. Increasingly, owners would like to feed their canine companions a similar diet. A plant-based dietary pattern has been rep…
View article: Scoping review exploring the evidence base on <i>Vitis vinifera</i> toxicity in dogs after ingestion: Clinical effects, treatments and types of <i>V. vinifera</i>
Scoping review exploring the evidence base on <i>Vitis vinifera</i> toxicity in dogs after ingestion: Clinical effects, treatments and types of <i>V. vinifera</i> Open
Background Treatment of Vitis vinifera fruit (VVF) ingestion can be challenging due to no clear toxic dose, signalment factors and variable clinical signs. Current treatment guidance is generalised: decontamination, aggressive fluid therap…
View article: Exploring the evidence base on grape (Vitis vinifera; VV) toxicity in dogs after ingestion - clinical effects, treatments, and types of VV fruit (VVF) implicated: A scoping review
Exploring the evidence base on grape (Vitis vinifera; VV) toxicity in dogs after ingestion - clinical effects, treatments, and types of VV fruit (VVF) implicated: A scoping review Open
Clinical abstract presented at BSAVA Congress 2024. See full text for abstract and see clinical abstract sessions for a recording of the presentation. Abstracts are presented as supplied and have not been edited. Objectives To scope clinic…
View article: Cardiovascular Fitness and Stride Acceleration in Race-Pace Workouts for the Prediction of Performance in Thoroughbreds
Cardiovascular Fitness and Stride Acceleration in Race-Pace Workouts for the Prediction of Performance in Thoroughbreds Open
In-training racehorse physiological data can be leveraged to further explore race-day performance prediction. To date, no large retrospective, observational study has analysed whether in-training speed and heart rate recovery can predict r…
View article: Late-spring Turfgrass Establishment without Herbicides
Late-spring Turfgrass Establishment without Herbicides Open
Spring establishment of turfgrass that is managed without herbicides is subject to weed competition, resulting in reduced turfgrass cover. The objective of this experiment was to find an acceptable method for spring turfgrass establishment…
View article: Effect of Plant Growth Regulators on Creeping Bentgrass during Heat, Salt, and Combined Stress
Effect of Plant Growth Regulators on Creeping Bentgrass during Heat, Salt, and Combined Stress Open
Creeping bentgrass ( Agrostis stolonifera L.) is a turfgrass species that is widely used on golf courses throughout the United States. In field settings, plants are often subjected to more than one stress at a time, and studying stresses i…
View article: Alterations in Antioxidant Micronutrient Concentrations in Placental Tissue, Maternal Blood and Urine and the Fetal Circulation in Pre-eclampsia
Alterations in Antioxidant Micronutrient Concentrations in Placental Tissue, Maternal Blood and Urine and the Fetal Circulation in Pre-eclampsia Open
Trace elements such as selenium and zinc are vital components of many enzymes, including endogenous antioxidants, and can interact with each other. Women with pre-eclampsia, the hypertensive disease of pregnancy, have been reported as havi…
View article: Locomotory Profiles in Thoroughbreds: Peak Stride Length and Frequency in Training and Association with Race Outcomes
Locomotory Profiles in Thoroughbreds: Peak Stride Length and Frequency in Training and Association with Race Outcomes Open
Racehorses competing in short (i.e., ‘sprinters’), middle- or longer-distance (i.e., ‘stayers’) flat races are assumed to have natural variation in locomotion; sprinters having an innately shorter stride than stayers. No study has objectiv…
View article: Does sex of the jockey influence racehorse physiology and performance
Does sex of the jockey influence racehorse physiology and performance Open
The racing industry is supported by a predominance of female stablehands and work riders, but few become professional jockeys. Female jockeys have recently had notable race success. No study has assessed whether the sex of the rider may su…
View article: Impact of <scp>COVID</scp>‐19 on student attainment and pedagogical needs when undertaking independent scientific research
Impact of <span>COVID</span>‐19 on student attainment and pedagogical needs when undertaking independent scientific research Open
Research is often an essential component of completing a veterinary medicine degree, with universities worldwide aiming to teach students a variety of techniques and general research comprehension and skills. As universities worldwide navi…
View article: Estimating short and longer-term exposure of domestic cats to dietary iodine fluctuation
Estimating short and longer-term exposure of domestic cats to dietary iodine fluctuation Open
Hyperthyroidism is a common endocrinopathy of domestic felines. In humans, toxic nodular goitre is pathophysiologically similar to feline hyperthyroidism and can be caused by chronically low or fluctuating dietary iodine intake. The aetiop…
View article: Development and the art of nutritional maintenance
Development and the art of nutritional maintenance Open
Development from early conceptus to a complex, multi-cellular organism is a highly ordered process that is dependent on an adequate supply of nutrients. During this process, the pattern of organ growth is robust, driven by a genetic bluepr…
View article: Cardiovascular and locomotory parameters during training in Thoroughbred racehorses: a multi-national study
Cardiovascular and locomotory parameters during training in Thoroughbred racehorses: a multi-national study Open
Studies assessing concurrent speed, cardiovascular physiology and biomechanical parameters in racehorses during training have been rarely reported, mostly due to a lack of available comprehensive technology. Here, using a validated device …
View article: Does sex of the jockey influence racehorse physiology and performance.
Does sex of the jockey influence racehorse physiology and performance. Open
Background Studies assessing the effect of the rider’s sex on racehorse performance and physiology during training have not been reported, mostly due to the paucity of available data for female participants within the sport. Here, using a …
View article: Does sex of the jockey influence racehorse physiology and performance
Does sex of the jockey influence racehorse physiology and performance Open
Studies assessing the effect of the rider’s sex on racehorse performance and physiology during training have not been reported, mostly due to the paucity of available data for female participants within the sport. Here, using a validated s…
View article: Intra-tracheal multiplexed sensing of contact pressure and perfusion
Intra-tracheal multiplexed sensing of contact pressure and perfusion Open
Incorrect endotracheal tube (ETT) cuff inflation pressure causes significant problems for intubated patients. The technical development and first in vivo use of a smart ETT for measurements at the cuff-trachea interface during mechanical v…
View article: Increased Placental Cell Senescence and Oxidative Stress in Women with Pre-Eclampsia and Normotensive Post-Term Pregnancies
Increased Placental Cell Senescence and Oxidative Stress in Women with Pre-Eclampsia and Normotensive Post-Term Pregnancies Open
Up to 11% of pregnancies extend to post-term with adverse obstetric events linked to pregnancies over 42 weeks. Oxidative stress and senescence (cells stop growing and dividing by irreversibly arresting their cell cycle and gradually agein…
View article: Maternal protein restriction affects fetal ovary development in sheep
Maternal protein restriction affects fetal ovary development in sheep Open
Maternal malnutrition has important developmental consequences for the foetus. Indeed, adverse fetal ovarian development could have lifelong impact, with potentially reduced ovarian reserve and fertility of the offspring. This study invest…