David S. Goldfarb
YOU?
Author Swipe
View article: Real-world burden of primary hyperoxaluria with chronic kidney disease in the United States: a retrospective administrative claims analysis
Real-world burden of primary hyperoxaluria with chronic kidney disease in the United States: a retrospective administrative claims analysis Open
Background Primary hyperoxaluria (PH) is a family of three rare, autosomal recessive genetic disorders that can result in recurrent kidney stones, progressive chronic kidney disease (CKD), and kidney failure. PH prevalence is underestimate…
View article: Questionable role of opioids for analgesia in renal colic and its urological interventions
Questionable role of opioids for analgesia in renal colic and its urological interventions Open
Objectives To review the different analgesic modalities and benefits of non‐opioid pain management options as well as their evidence‐based, established superiority, compared to opioid medications. Materials We review the updated literature…
View article: Treatment preferences among individuals with primary hyperoxaluria type 1 (PH1): a real-world study
Treatment preferences among individuals with primary hyperoxaluria type 1 (PH1): a real-world study Open
Background Primary hyperoxaluria type 1 (PH1) is a rare genetic disorder causing excessive oxalate production, damaging kidneys and other organs. Nedosiran, launched in the U.S. for individuals with PH1 (≥ 9 years of age; estimated glomeru…
View article: Perspectives on Water Utilization in Hemodialysis: Nephrologists’ Responsibilities
Perspectives on Water Utilization in Hemodialysis: Nephrologists’ Responsibilities Open
Background: Hemodialysis is a water-intense procedure, needing large quantities of water for preparation of small volumes of dialyzate. The resulting large volumes of reject water are usually discarded. With the rising water crisis both in…
View article: Risk Factors for Severe Disease Among Children Hospitalized With Respiratory Syncytial Virus
Risk Factors for Severe Disease Among Children Hospitalized With Respiratory Syncytial Virus Open
Importance A resurgence of respiratory syncytial virus (RSV)–associated acute respiratory tract infection (ARI) was observed in 2022 and 2023 after the COVID-19 pandemic. Changes in the demographic characteristics, disease severity, and ou…
View article: Surveillance for Infection and Colonization due to Candida spp. at a Tertiary Referral Hospital in Botswana: 2022-2024
Surveillance for Infection and Colonization due to Candida spp. at a Tertiary Referral Hospital in Botswana: 2022-2024 Open
Introduction: Candida spp. are a common cause of healthcare-associated infections globally and Candida bloodstream infections (BSI) are associated with ∼30% mortality. Candida auris, a multidrug-resistant yeast which can be challenging to …
View article: Multiomics Assessment of the Gut Microbiome in Rare Hyperoxaluric Conditions
Multiomics Assessment of the Gut Microbiome in Rare Hyperoxaluric Conditions Open
The composition and inferred activity of oxalate-degrading microbiota were differentially associated with host clinical conditions. Identifying these changes improves our understanding of the relationships between dietary constituents, mic…
View article: Predictors of Acute Kidney Injury (AKI) among COVID-19 Patients at the US Department of Veterans Affairs: The Important Role of COVID-19 Vaccinations
Predictors of Acute Kidney Injury (AKI) among COVID-19 Patients at the US Department of Veterans Affairs: The Important Role of COVID-19 Vaccinations Open
Background: There are knowledge gaps about factors associated with acute kidney injury (AKI) among COVID-19 patients. To examine AKI predictors among COVID-19 patients, a retrospective longitudinal cohort study was conducted between Januar…
View article: Thiazide Use for the Prevention of Recurrent Calcium Kidney Stones
Thiazide Use for the Prevention of Recurrent Calcium Kidney Stones Open
Among individuals with calcium oxalate or calcium phosphate stones, the recurrence rate is approximately 15% per year. Higher urine calcium is a well-documented risk factor for calcium oxalate and calcium phosphate stones, and arbitrary cu…
View article: Correction to: Effect of a high-citrate beverage on urine chemistry in patients with calcium kidney stones
Correction to: Effect of a high-citrate beverage on urine chemistry in patients with calcium kidney stones Open
View article: Correction to: Nedosiran in primary hyperoxaluria subtype 3: results from a phase I, single-dose study (PHYOX4)
Correction to: Nedosiran in primary hyperoxaluria subtype 3: results from a phase I, single-dose study (PHYOX4) Open
View article: Nedosiran in primary hyperoxaluria subtype 3: results from a phase I, single-dose study (PHYOX4)
Nedosiran in primary hyperoxaluria subtype 3: results from a phase I, single-dose study (PHYOX4) Open
View article: Healthcare utilization, quality of life, and work productivity associated with primary hyperoxaluria: a cross-sectional web-based US survey
Healthcare utilization, quality of life, and work productivity associated with primary hyperoxaluria: a cross-sectional web-based US survey Open
Primary hyperoxaluria (PH) is a family of ultra-rare, autosomal recessive, metabolic disorders associated with frequent kidney stones, chronic kidney disease and kidney failure, and serious complications due to systemic oxalosis, resulting…
View article: A Summary of Current Guidelines and Future Directions for Medical Management and Monitoring of Patients with Cystinuria
A Summary of Current Guidelines and Future Directions for Medical Management and Monitoring of Patients with Cystinuria Open
Cystinuria is the most common genetic cause of recurrent kidney stones. As the result of a genetic defect in proximal tubular reabsorption of filtered cystine, increased urine levels of the poorly soluble amino acid result in recurrent cys…
View article: Extracorporeal treatment for ethylene glycol poisoning: systematic review and recommendations from the EXTRIP workgroup
Extracorporeal treatment for ethylene glycol poisoning: systematic review and recommendations from the EXTRIP workgroup Open
View article: Epidemiology of Kidney Stones
Epidemiology of Kidney Stones Open
In the past two decades, major breakthroughs that improve our understanding of the pathophysiology and therapy of kidney stones (KS) have been lacking. The disease continues to be challenging for patients, physicians, and healthcare system…
View article: Effects of Microbiome Depletion on Host Oxalate Metabolism
Effects of Microbiome Depletion on Host Oxalate Metabolism Open
View article: Accurate 24-h urine cystine quantification for patients on cystine-binding thiol drugs
Accurate 24-h urine cystine quantification for patients on cystine-binding thiol drugs Open
Cystinuria is a rare disorder resulting in development of recurrent kidney stones, adversely affecting patient quality of life. The goal of cystinuria management is to reduce stone formation by increasing cystine solubility in urine, which…
View article: Extracorporeal Treatment for Methotrexate Poisoning: Systematic Review and Recommendations from the EXTRIP Workgroup.
Extracorporeal Treatment for Methotrexate Poisoning: Systematic Review and Recommendations from the EXTRIP Workgroup. Open
Methotrexate is used in the treatment of many malignancies, rheumatological diseases, and inflammatory bowel disease. Toxicity from use is associated with severe morbidity and mortality. Rescue treatments include intravenous hydration, fol…
View article: Extracorporeal Treatment for Methotrexate Poisoning
Extracorporeal Treatment for Methotrexate Poisoning Open
Methotrexate is used in the treatment of many malignancies, rheumatological diseases, and inflammatory bowel disease. Toxicity from use is associated with severe morbidity and mortality. Rescue treatments include intravenous hydration, fol…
View article: Extracorporeal Treatment for Gabapentin and Pregabalin Poisoning: Systematic Review and Recommendations From the EXTRIP Workgroup
Extracorporeal Treatment for Gabapentin and Pregabalin Poisoning: Systematic Review and Recommendations From the EXTRIP Workgroup Open
View article: Comprehensive Genetic Analysis Reveals Complexity of Monogenic Urinary Stone Disease
Comprehensive Genetic Analysis Reveals Complexity of Monogenic Urinary Stone Disease Open
View article: Effect of antibiotic treatment on Oxalobacter formigenes colonization of the gut microbiome and urinary oxalate excretion
Effect of antibiotic treatment on Oxalobacter formigenes colonization of the gut microbiome and urinary oxalate excretion Open
The incidence of kidney stones is increasing in the US population. Oxalate, a major factor for stone formation, is degraded by gut bacteria reducing its intestinal absorption. Intestinal O. formigenes colonization has been associated with …
View article: Challenging patient phenotypes in the management of anaemia of chronic kidney disease
Challenging patient phenotypes in the management of anaemia of chronic kidney disease Open
Several therapies provide promising opportunities to address gaps with a standard of care, including hypoxia-inducible factor prolyl hydroxylase inhibitors, which stimulate haematopoiesis through promoting modest increases in serum erythro…
View article: Extracorporeal treatment for poisoning to beta-adrenergic antagonists: systematic review and recommendations from the EXTRIP workgroup
Extracorporeal treatment for poisoning to beta-adrenergic antagonists: systematic review and recommendations from the EXTRIP workgroup Open
View article: Dietary Inflammatory Index and Cardiovascular Disease Risk Factors in Patients With Chronic Kidney Disease and Type 2 Diabetes
Dietary Inflammatory Index and Cardiovascular Disease Risk Factors in Patients With Chronic Kidney Disease and Type 2 Diabetes Open
OBJECTIVES: Inflammation is associated with several chronic diseases, including chronic kidney disease (CKD) and type 2 diabetes (T2D). Because dietary choices may impact chronic inflammation, the Dietary Inflammatory Index (DII) was devel…
View article: A Report of Two Cases: Unlearning Lactic Acidosis
A Report of Two Cases: Unlearning Lactic Acidosis Open
Introduction: The term “lactic acidosis” reinforces the misconception that lactate contributes to acidemia. Although it is common to discover an anion gap acidosis with a concomitant elevated lactate concentration, the two are not mutually…
View article: Effect of antibiotic treatment on Oxalobacter formigenes colonization of the gut microbiome and urinary oxalate excretion
Effect of antibiotic treatment on Oxalobacter formigenes colonization of the gut microbiome and urinary oxalate excretion Open
Background: The incidence of kidney stones is increasing in the US population. Oxalate, a major factor for stone formation, is degraded by gut bacteria reducing its intestinal absorption. Intestinal O. formigenes colonization has been asso…
View article: Peripapillary Neuroendocrine Carcinoma Metastasis: A Novel Approach to Treatment
Peripapillary Neuroendocrine Carcinoma Metastasis: A Novel Approach to Treatment Open
Peripapillary and circumpapillary retinal intraocular metastases are rare and present a treatment challenge for ophthalmologists because of the high risk of iatrogenic injury to the optic nerve. There are no clear guidelines on the managem…
View article: Bariatric surgery in a patient with cystinuria
Bariatric surgery in a patient with cystinuria Open
We recently encountered concern about the safety of bariatric surgery for a patient with cystinuria. Bariatric surgery procedures include those that cause malabsorption, like the Roux-en-Y gastric bypass procedure, and restrictive operatio…